Top 5 — Ranked by GLP-1 Evidence
Very Strong
Whey Concentrate
Muscle Growth and Repair
20–40 g post-workout for muscle growth/recovery; 1.6–2 g/kg/day total protein for ath
Very Strong
Psyllium Husk (Plantago ovata)
Blood sugar and postprandial glucose blunting
5–15 g/day psyllium husk (1–3 teaspoons); FDA cholesterol claim requires ≥7 g/day; ta
Strong
Berberine
Blood Sugar Regulation
500–1,500 mg per day, often divided into 2–3 doses taken with meals to improve absorp
Strong
Capsaicin / Capsicum Extract (Capsimax®)
Appetite reduction and satiety
100–200 mg/day Capsimax® (2% capsaicinoids = 2–4 mg active capsaicinoids); timing: 30
Strong
Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)
Appetite suppression
100 mg/day Capsimax (providing 2 mg total capsaicinoids) is the standard clinical dos
📈 Fastest Growing GLP-1 Support Ingredients
Ingredients positioned for use alongside GLP-1 medications — protein retention and satiety support.
Trending
Very Strong
Whey Concentrate
Muscle Growth and Repair
20–40 g post-workout for muscle growth/recovery; 1.6–2 g/kg/day total protein for athletes;…
Trending
Strong
Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)
Resting energy expenditure (~116 kcal/day)
100 mg/day Capsimax (providing 2 mg total capsaicinoids) is the standard clinical dose used in…
Trending
Strong
Glucomannan (Konjac Root Fiber)
Weight loss and appetite suppression
3–4 g/day before meals (1 g three times daily, 30 minutes before meals with 250 mL water);…
🔬 Future GLP-1 Support Ingredients to Watch
Lower current evidence but active research underway — these may become top picks within 2–3 years.
Watch
Moderate
GlucoVantage® (Dihydroberberine)
Superior bioavailability over standard berberine
100–200 mg/day (equivalent to 500–1,000 mg standard berberine); taken before meals
Watch
Moderate
Metabolaid® (Hibiscus + Lemon Verbena)
AMPK activation and fat oxidation
500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before exercise or with…
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Limited
Akkermansia muciniphila
GLP-1 secretion via P9 protein (mechanistic)
Depommier 2019: 10¹⁰ CFU/day pasteurized × 3 months. Most products: 10⁸-10⁹ CFU/day.…
All GLP-1 Support Ingredients (17)
Very Strong
Whey Concentrate
Muscle Growth and Repair
20–40 g post-workout for muscle growth/recovery; 1.6–2 g/kg/day total protein for ath
Very Strong
Psyllium Husk (Plantago ovata)
Blood sugar and postprandial glucose blunting
5–15 g/day psyllium husk (1–3 teaspoons); FDA cholesterol claim requires ≥7 g/day; ta
Strong
Berberine
Blood Sugar Regulation
500–1,500 mg per day, often divided into 2–3 doses taken with meals to improve absorp
Strong
Capsaicin / Capsicum Extract (Capsimax®)
Appetite reduction and satiety
100–200 mg/day Capsimax® (2% capsaicinoids = 2–4 mg active capsaicinoids); timing: 30
Strong
Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)
Appetite suppression
100 mg/day Capsimax (providing 2 mg total capsaicinoids) is the standard clinical dos
Strong
Glucomannan (Konjac Root Fiber)
Weight loss and appetite suppression
3–4 g/day before meals (1 g three times daily, 30 minutes before meals with 250 mL wa
Strong
Chromax® (Chromium Picolinate)
Insulin sensitivity and blood glucose management
200–1,000 mcg/day chromium as Chromax® chromium picolinate; insulin sensitivity: 200–
Moderate
Inulin
Improved Digestive Health
2–10 g/day for prebiotic/gut microbiome effects; gradual dose increase recommended to
Moderate
Banaba Leaf (Lagerstroemia speciosa)
Fasting Blood Glucose Reduction
MOST TRIALS: 32-48 mg/day extract 1% corosolic acid (= 0.32-0.48 mg corosolic acid/da
Moderate
Acacia Fiber (inavea™ Pure Acacia)
Satiety and weight management support
RANGE: 5-30 g/day. PREBIOTIC (bifidogenic): ~10 g/day onset. SATIETY/METABOLIC: 15-30
Moderate
White Mulberry (Morus alba)
Postprandial Glucose Spike Reduction
LOWN 2017: Reducose® 5% DNJ 250 mg/dose (12.5 mg DNJ) + 50 g maltodextrin. HWANG 2016
Moderate
Arabinoxylan (Arrabina®)
Blood sugar and postprandial glucose blunting
4–15 g/day; blood sugar management: 8–15 g/day with meals; immune studies: 4–10 g/day
Moderate
GlucoVantage® (Dihydroberberine)
Superior bioavailability over standard berberine
100–200 mg/day (equivalent to 500–1,000 mg standard berberine); taken before meals
Moderate
MCT Oil (Medium-Chain Triglycerides)
Weight management and satiety
15–30 mL/day (1–2 tablespoons); start with 5–10 mL and increase gradually to avoid GI
Moderate
Metabolaid® (Hibiscus + Lemon Verbena)
Appetite regulation and satiety
500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before exercis
Limited
Akkermansia muciniphila
GLP-1 secretion via P9 protein (mechanistic)
Depommier 2019: 10¹⁰ CFU/day pasteurized × 3 months. Most products: 10⁸-10⁹ CFU/day.
Limited
Yacon Syrup
Increased Defecation Frequency and Satiety
PIVOTAL: 0.14 g FOS/kg/day × 120 d (~10 g FOS = 20-25 g syrup for 70-kg adult). TOXIC