Top 5 — Ranked by Evidence
Very Strong
Vitamin C
Immune System Support
75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day; lip
Very Strong
Vitamin D
Autoimmune disease prevention
RDA: 600-800 IU/day. Optimal serum 25(OH)D: 30-50 ng/mL (typically 1,000-2,000 IU/day
Very Strong
Zinc
Immune System Support
8–11 mg/day (RDA); therapeutic: 25–40 mg/day elemental zinc; upper limit 40 mg/day; a
Very Strong
BLIS K12® (Streptococcus salivarius for ENT — Stratum Nutrition)
Natural Immune System Support
1 billion CFU/day BLIS K12 (research-validated)
Very Strong
EpiCor® (Postbiotic Yeast Fermentate — Cargill)
Gut-immune axis support
500 mg/day EpiCor (research-validated)
📈 Fastest Growing Immune Support Ingredients
Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.
Trending
Very Strong
EpiCor® (Postbiotic Yeast Fermentate — Cargill)
Constipation and GI discomfort reduction
500 mg/day EpiCor (research-validated)
Trending
Very Strong
BLIS K12® (Streptococcus salivarius for ENT — Stratum Nutrition)
Ear, Nose, Throat (ENT) Health
1 billion CFU/day BLIS K12 (research-validated)
Trending
Strong
Black Seed Oil
Blood pressure reduction
Standard cardiometabolic dose: 500-2,000 mg/day cold-pressed black seed oil. Higher-dose…
🔬 Future Immune Support Ingredients to Watch
Lower current evidence but active research underway — these may become top picks within 2–3 years.
Watch
Strong
ResistAid® (Larch Arabinogalactan — Lonza)
Cold and Flu Incidence Reduction
1.5-4.5 g/day ResistAid (research-validated)
Watch
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,200 mg…
Watch
Strong
Bifidobacterium breve
Atopic dermatitis and food allergy management in infants
INFANT AD (M-16V Morinaga): 1×10⁹ CFU/day × 1 mo. PRETERM (M-16V): 1×10⁹ CFU/day NICU. ADULT…
All Immune Support Ingredients (133)
Very Strong
Vitamin C
Immune System Support
75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day; lip
Very Strong
Vitamin D
Autoimmune disease prevention
RDA: 600-800 IU/day. Optimal serum 25(OH)D: 30-50 ng/mL (typically 1,000-2,000 IU/day
Very Strong
Zinc
Immune System Support
8–11 mg/day (RDA); therapeutic: 25–40 mg/day elemental zinc; upper limit 40 mg/day; a
Very Strong
BLIS K12® (Streptococcus salivarius for ENT — Stratum Nutrition)
Natural Immune System Support
1 billion CFU/day BLIS K12 (research-validated)
Very Strong
EpiCor® (Postbiotic Yeast Fermentate — Cargill)
Gut-immune axis support
500 mg/day EpiCor (research-validated)
Very Strong
Ferrous Sulfate
Established Standard for Iron Deficiency
60-200 mg elemental iron/day for adult IDA treatment (often 325 mg ferrous sulfate =
Very Strong
Vitamin A
Immune function
700–900 mcg RAE/day (adults); upper limit 3,000 mcg RAE/day
Strong
Beta-Glucans (Oat & Yeast-Derived)
Innate immune activation (mechanism)
Cholesterol (FDA claim): 3 g/day oat β-glucan. Immune (Wellmune®): 250-500 mg/day yea
Strong
Clostridium butyricum MIYAIRI 588 (CBM588 / MIYA-BM® / Butirrisan®)
Butyrate production in the gut
Standard dose: 20-80 mg/day of MIYA-BM® powder providing 1-4×10⁸ CFU. Adult AAD preve
Strong
Bacillus clausii (Enterogermina® / Erceflora)
Acute diarrhea treatment
Standard dose: 2 billion spores (2×10⁹ CFU) 2-3 times daily as oral suspension. AAD p
Strong
Bifidobacterium animalis subsp. lactis (BB-12 / HN019)
Immune function and respiratory infection reduction
1–10 billion CFU/day (BB-12); 17.2 billion CFU/day (HN019 in constipation studies)
Strong
Bifidobacterium breve
Atopic dermatitis and food allergy management in infants
INFANT AD (M-16V Morinaga): 1×10⁹ CFU/day × 1 mo. PRETERM (M-16V): 1×10⁹ CFU/day NICU
Strong
Black Seed Oil
Blood pressure reduction
Standard cardiometabolic dose: 500-2,000 mg/day cold-pressed black seed oil. Higher-d
Strong
Calendula (Pot Marigold)
Prevention of acute radiation-induced dermatitis (Pivotal RCT)
RADIATION DERMATITIS: Boiron Pommade au Calendula 2×/day during radiotherapy. WOUND/S
Strong
Escherichia coli Nissle 1917 (Mutaflor®)
Ulcerative colitis maintenance
Ulcerative colitis maintenance: 100 mg twice daily (5×10⁹ CFU/capsule × 2/day) per Mu
Strong
Garlic (Allium sativum)
Antimicrobial and immune activity
600–1,200 mg/day aged garlic extract (AGE); raw garlic equivalent: 2–4 cloves/day; al
Strong
Kyolic® (Aged Garlic Extract — Wakunaga)
Immune system support
Standard cardiovascular protocol: 1,200-2,400 mg/day Kyolic® in divided doses. Differ
Strong
Lactobacillus fermentum CECT5716 (Lc40 / Hereditum®)
Mastitis prevention in breastfeeding women
Mastitis prevention/treatment: 3×10⁹ CFU/day for 21 days minimum, ideally throughout
Strong
Lactobacillus rhamnosus GG (LGG)
Immune function and respiratory infection reduction
10–20 billion CFU/day; 5–10 billion CFU/day commonly used in pediatric protocols
Strong
Limosilactobacillus reuteri DSM 17938 (BioGaia Protectis®)
Infant colic crying time reduction
Infants: 100 million CFU (1×10⁸) once daily as drops (BioGaia Protectis® dosing). Chi
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,2
Strong
ParActin® (Andrographis Extract — HP Ingredients)
Immune system modulation
Standard formulation use: 100-300 mg ParActin® once or twice daily. Take with food to
Strong
ResistAid® (Larch Arabinogalactan — Lonza)
Antibody Response Enhancement
1.5-4.5 g/day ResistAid (research-validated)
Strong
Saccharomyces boulardii
Antibiotic-associated diarrhea prevention
250–500 mg twice daily (5–10 billion CFU/day); 250 mg three times daily for C. diffic
Strong
Tea Tree Oil
Mild-to-moderate acne treatment
TOPICAL ACNE: 5% TTO gel 1-2×/day. DANDRUFF: 5% shampoo daily. ORAL/PERIODONTITIS: 0.
Strong
Aged Garlic Extract
Blood pressure reduction in hypertension
Standard cardiovascular dose: 600-2,400 mg/day AGE standardized to S-allyl cysteine c
Strong
Andrographis
Upper respiratory tract infections
Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% androgr
Strong
BetaVia™ (Euglena gracilis Algae Beta-1,3-Glucan — Kemin)
Fewer URTI sick days (90-day RCT)
Pivotal trial: 367 mg/day BetaVia Complete for 90 days. Kemin recommended dosing: 375
Strong
Bifidobacterium bifidum
Immune modulation and balanced inflammation
IBS (live MIMBb75): 1×10⁹ CFU/day for 4+ weeks; IBS (heat-inactivated MIMBb75 / SYN-H
Strong
Bioferrin® (Lactoferrin — Glanbia)
Immune Support
100-1000 mg/day lactoferrin (varies by application; immune support typical 100-300 mg
Strong
Ferrous Bisglycinate
Superior GI Tolerability
25-60 mg elemental iron/day; pregnancy: 25-30 mg/day often sufficient
Strong
Ferrous Fumarate
Higher Elemental Iron Content
60-200 mg elemental iron/day for adult IDA (often 200 mg ferrous fumarate = 65 mg ele
Strong
Gingever® (High-Potency Ginger Extract — OmniActive)
Occasional constipation (Eraiah 2024)
280 mg/day Gingever (Eraiah 2024 constipation trial, taken nightly after dinner for 8
Strong
L-OptiZinc® (Zinc Mono-L-Methionine — Lonza)
Immune System Support
10-30 mg elemental zinc/day (per L-OptiZinc product specification)
Strong
Probiotics (Multi-strain Blends)
Immune modulation
1–10 billion CFU/day maintenance; up to 50 billion CFU/day therapeutic
Strong
Selenium
Immune function
55 mcg/day (RDA); therapeutic studies: 100–200 mcg/day; upper limit 400 mcg/day
Strong
Selenium Yeast (High-Selenium Yeast)
Used in Major Cancer Trials
100-200 µg elemental selenium/day; SELECT used 200 µg/day; NPC trial used 200 µg/day
Strong
SelenoForce® (Selenium-Enriched Yeast — Sabinsa)
Immune function support
100-200 mcg/day elemental selenium from SelenoForce. RDA: 55 mcg/day; tolerable upper
Strong
Selenomethionine
Hashimoto's Thyroiditis Adjunct
100-200 µg elemental selenium/day; Hashimoto's trials typically 200 µg/day
Strong
Shiitake Mushroom (Lentinula edodes)
Immune Modulation
1,000-3,000 mg/day mushroom extract; lentinan is typically given INJECTABLY (1-2 mg/w
Strong
Vitamin E
Immune modulation
15 mg/day (RDA); therapeutic studies use 400–1,000 IU/day
Strong
Zinc Acetate
Common Cold Treatment (Cold-Eeze)
13–23 mg elemental zinc per lozenge for cold use (75–100 mg/day total); 50 mg three t
Strong
Zinc Gluconate
Common Cold Symptom Reduction
15–50 mg elemental zinc/day for general supplementation; for cold treatment 13.3–23 m
Strong
BLIS M18® (Streptococcus salivarius for Oral Health — Stratum Nutrition)
Dental Health Support
1 billion CFU/day BLIS M18 (research-validated)
Strong
LactoSpore® (Heat-Stable Bacillus coagulans Probiotic)
Immune system support
1–4 billion CFU/day LactoSpore® Bacillus coagulans; IBS and gut health: 2 billion CFU
Strong
PeakO2® (Adaptogenic Mushroom Blend)
Immune support and adaptogenic stress resilience
1–4g/day for ongoing use; 4g/day for clinical performance benefits (21-day loading);
Strong
Spectramune® (Immune Defense Complex)
Broad-spectrum immune defense
Per Spectramune® clinical dosing; PLT Health Solutions product specifications
Moderate
Quercetin
Immune Support
500–1,000 mg/day; absorption enhanced significantly with vitamin C or bromelain; quer
Moderate
Polypodium Leucotomos
Immune Modulation
Typically dosed at 240–480 mg/day
Moderate
Echinacea
Immune System Support
300–500 mg three times daily (900–1,500 mg/day) during illness; prevention: 300 mg/da
Moderate
Cranberry
Urinary Tract Health
400–500 mg/day standardized extract (PAC 36 mg); for UTI prevention: daily long-term;
Moderate
Ginseng
Immune System Support
200–400 mg/day standardized extract (ginsenosides ≥4–7%); American ginseng: 100–200 m
Moderate
Lion's Mane Mushroom
Immune Support
500–3,000 mg/day dried mushroom powder; extract: 250–500 mg/day (standardized to >30%
Moderate
Colostrum
Immune Support
10-20g per day
Moderate
L-Glutamine
IBS-D and post-infectious IBS — strongest gut evidence
Gut barrier: 15 g/day (3x5g). Permeability (2024 meta): >30 g/day, <2 weeks. Sickle c
Moderate
Shatavari (Asparagus racemosus / Xeya®)
Immune support — modest evidence
500-1,000 mg/day standardized root extract. Lactation: 300 mg twice daily. PCOS (CL22
Moderate
Bovine Colostrum
Exercise-induced gut permeability — strongest evidence
Athletic gut/immune: 20-60 g/day × 4-12 weeks. Pediatric diarrhea: 7-14 g/day. Choose
Moderate
Neem (Azadirachta indica)
Plaque and Gingivitis Reduction (RCT-Confirmed)
PINGALI 2020 T2DM: 125/250/500 mg standardized neem BID = 250-1000 mg/day × 12 wk + m
Moderate
Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)
NSCLC perioperative immune modulation (multicenter pilot)
ANDOSAN™ ORAL: 60 mL/day liquid extract × 7 weeks (multiple myeloma protocol). NSCLC
Moderate
Aged Black Garlic ABG10+® (Pharmactive)
Blood pressure reduction in hypertensive adults
Standard dose: 250-500 mg/day ABG10+® standardized aged black garlic extract. Cardiov
Moderate
Bifidobacterium longum
Stress reduction and emotional regulation (psychobiotic effects)
1–10 billion CFU/day; 1714 strain studies use 1 billion CFU/day for psychobiotic effe
Moderate
Codonopsis lanceolata (Deodeok / Korean Bonnet Bellflower)
Sarcopenia 12-week RCT protocol (Kyung Hee)
TCM TYPICAL: 9-15 g/day root decoction. SARCOPENIA RCT (Park 2022 protocol): 750 mg w
Moderate
Codonopsis pilosula (Dang Shen / Poor Man's Ginseng)
Chronic fatigue 8-week pilot RCT (Frontiers in Pharmacology 2021)
TCM TYPICAL: 9-15 g/day root decoction. oncology adjunct: oral liquid (approved Chine
Moderate
ImmuseLC-Plasma (Lactococcus lactis strain Plasma)
Plasmacytoid dendritic cell activation
100 billion (10¹¹) heat-killed L. lactis strain Plasma/day standard RCT dose. Kirin i
Moderate
Kutki (Picrorhiza kurroa)
Hepatoprotection — chronic and acute liver disease
TRADITIONAL AYURVEDIC: 250-500 mg dried rhizome 2-3×/day OR 1-3 g/day decoction. STAN
Moderate
Lactobacillus acidophilus
Lactose intolerance symptom reduction
1–10 billion CFU/day for general use; up to 50 billion CFU/day in IBS or vaginal heal
Moderate
Lactobacillus johnsonii La1 (NCC533 / CNCM I-1225)
H. pylori suppression supernatant trial
MICHETTI 1999 H. PYLORI: La1 whey-based culture supernatant ~10⁹ CFU/mL adults. FERME
Moderate
Lactobacillus paracasei (Multi-Strain Specialist)
Upper respiratory symptom duration
L. CASEI 431® RESPIRATORY: ≥1×10⁹ CFU/day × 42 days. KW3110 POLLEN ALLERGY: 4×10¹⁰ CF
Moderate
Lactobacillus plantarum
Immune function in athletes and stressed populations
10–50 billion CFU/day; 299v strain typically 20 billion CFU/day; weight management st
Moderate
Lactobacillus salivarius (Multi-Strain)
CECT5713 immune support (Sierra et al.)
ORAL HEALTH (WB21): 2.0×10⁹ CFU/day × 2 weeks (caries). PERIODONTAL (heat-killed CP33
Moderate
Multivitamin / Multimineral
Reduced total cancer incidence in older men (PHS II)
STANDARD: 1 tablet/day MVMM ~100% DV most vitamins, 25-100% DV minerals. PHS II + COS
Moderate
Phellinus linteus (Meshimakobu / Sanghuang)
Immune improvement RCT (, LDH cytotoxicity)
: PL mycelium extract 1,000 mg/day × 8 weeks (n=98, KCTC0399BP strain). IMMUNITY RCT:
Moderate
Rosmarinic Acid
Reduced seasonal allergic rhinitis symptoms
ALLERGIC RHINITIS: 50-200 mg/day Perilla × 21 d. AD COGNITION (Noguchi-Shinohara): 50
Moderate
Squalene
Cholesterol reduction in elderly hypercholesterolemia
CV: 860 mg/day × 20 wk hypercholesterolemia. STRANDBERG 1990: 900 mg/day. PK: 500 mg
Moderate
Streptococcus salivarius
Recurrent strep throat and tonsillitis prevention (K12)
1 billion CFU/day (K12 lozenge); 1 billion CFU/day (M18 lozenge)
Moderate
Streptococcus thermophilus (Specific Strains)
ST36 immune + intestinal function support
ST81: 3 billion CFU/day. ST36: similar consumer dose. AAD prevention combination with
Moderate
AHCC (Active Hexose Correlated Compound)
Immune Cell Activation
1-3 g/day; 3 g/day used in HPV clearance trials (Smith 2019 — 6 months); 1-3 g/day fo
Moderate
Arabinoxylan (Arrabina®)
Immune system modulation
4–15 g/day; blood sugar management: 8–15 g/day with meals; immune studies: 4–10 g/day
Moderate
Astragalus (Astragalus membranaceus)
Immune system modulation and enhancement
ROOT: 2-6 g/day dried OR 250-500 mg/day standardized extract. IMMUNE: 500 mg BID. TA-
Moderate
Bacillus subtilis
Athletic recovery and immune support in athletes
1–10 billion CFU/day; DE111 commonly dosed at 1 billion CFU/day
Moderate
Bromelain
Anti-inflammatory and pain relief
200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d
Moderate
Butterbur (Petasites hybridus)
Migraine prevention
50–75 mg twice daily PA-free Petadolex® (75–150 mg/day) for migraine prevention; alle
Moderate
Cordyceps
Immune modulation
1,000–3,000 mg/day mycelium powder; 400–800 mg/day standardized extract
Moderate
Elderberry
Immune stimulation
600–900 mg extract/day during illness; 150–300 mg/day for prevention
Moderate
Eleuthero / Siberian Ginseng (Eleutherococcus senticosus)
Immune Function Modulation
300-1,200 mg/day standardized extract; root powder 1-3 g/day
Moderate
Ferrous Gluconate
Better GI Tolerability
50-300 mg elemental iron/day; often 325 mg ferrous gluconate = ~38 mg elemental Fe pe
Moderate
FucoMax® (Fucoidan from Brown Seaweed — BGG)
Immune System Modulation
Per BGG FucoMax product specification
Moderate
Goldenseal (Hydrastis canadensis)
Antimicrobial and immune support
500–1,000 mg/day dried root powder; standardized extract: 250–500 mg/day; typically u
Moderate
Heme Iron Polypeptide (HIP)
Distinct Absorption Pathway (HCP1)
10-22 mg elemental heme iron/day; Proferrin Forte = 11 mg elemental iron per tablet
Moderate
L-Lysine
Herpes simplex virus (HSV) suppression
500–3,000 mg/day; herpes suppression: 1,000–3,000 mg/day during outbreaks, 500–1,500
Moderate
Lactobacillus casei
Antibiotic-associated and C. difficile diarrhea prevention
10^9–10^10 CFU/day (Yakult provides 10^10 CFU/65mL bottle); 10–100 billion CFU/day in
Moderate
Maitake Mushroom (Grifola frondosa)
Immune Activation (D-Fraction)
1-3 mg D-fraction/kg body weight (50-300 mg D-fraction/day for typical adults); whole
Moderate
Olivactive® (Olive Leaf Extract for Immune Support)
Immune System Strengthening
Per Pharmactive product specification
Moderate
Reishi Mushroom
Immune modulation
1.5–9 g/day whole mushroom powder; 1–1.5 g/day standardized extract
Moderate
Setria® Glutathione
Immune system enhancement
250–500 mg/day; 250 mg shown effective for increasing blood glutathione levels
Moderate
Spirulina
Immune enhancement
1–8 g/day; most clinical trials use 2–4 g/day
Moderate
Thyme (Thymus vulgaris)
Acute Bronchitis Cough Reduction (RCT-Confirmed)
BRONCHIPRET® THYME-IVY: 5.4 mL × 3/day × 11 d. BRONCHIPRET® TP: 1 tablet × 3/day × 11
Moderate
Tinofend® (Tinospora cordifolia for Immune — Verdure)
Immune System Modulation
Per Verdure Tinofend product specification
Moderate
Tinospora Cordifolia (Tinofend®)
Immune system modulation
300 mg/day Tinofend® (standardized extract); traditional Ayurvedic dose: 1–3 g/day wh
Moderate
Turkey Tail Mushroom
Immune system activation
1–3 g/day PSK extract; 2–9 g/day whole mushroom powder
Moderate
Zinc Bisglycinate (Zinc Glycinate)
Immune Support
15–30 mg elemental zinc/day for general supplementation; up to 50 mg for short-term t
Moderate
Zinc Citrate
Immune Support
15–50 mg elemental zinc/day; toothpaste/mouthwash use 0.1–0.3% concentration
Moderate
Zinc Picolinate
Bioavailability
15–50 mg elemental zinc/day; for short-term immune/skin: up to 50 mg/day for 4–8 week
Moderate
Zinmax® (Premium Zinc Picolinate - Nutrition 21)
Immune Support
8-15 mg elemental zinc daily (typical zinc supplementation; therapeutic doses higher)
Moderate
AlvioLife® (Respiratory Health & Performance)
Immune and respiratory resilience
Per AlvioLife® clinical dosing; PLT Health Solutions product specifications
Moderate
Earthlight® (Whole Food Mushroom Vitamin D2)
Immune function support
250–1000 IU Vitamin D2 equivalent per serving as Earthlight®; dosing equivalent to 25
Moderate
Optibiome® BS50 (Bacillus subtilis MB40 — BIO-CAT Microbials)
Improved Immunity
Per BIO-CAT Optibiome BS50 product specification
Moderate
PROMUNEL® (Propolis Immune Extract)
Immune system modulation and activation
400–800 mg/day propolis extract; PROMUNEL® clinical dose per PLT specifications; immu
Moderate
SoWell™ (Postbiotic Heat-Killed Lactobacillus)
Shelf-stable immune modulation
Per SoWell™ product specifications; typical postbiotic dose 10–100 billion CFU equiva
Moderate
effera® (Human-Identical Lactoferrin)
Superior immune activation vs. bovine lactoferrin
Per effera® product specifications; Helaina clinical dosing; typical lactoferrin dose
Moderate
iXOS® (Xylooligosaccharides Prebiotic)
Metabolic and immune health benefits
1–2g/day iXOS® for prebiotic bifidogenic effects (much lower than other prebiotics at
Limited
Akkermansia muciniphila
GLP-1 secretion via P9 protein (mechanistic)
Depommier 2019: 10¹⁰ CFU/day pasteurized × 3 months. Most products: 10⁸-10⁹ CFU/day.
Limited
Chlorella
Immune function — preliminary evidence
General use: 3-6 g/day. NAFLD studies: 1.2-1.5 g/day × 3 months. Metabolic syndrome:
Limited
Humic Extract
Colonic microbiome modulation (clinical evidence)
Traditional/clinical doses: 100-500 mg/day humic acid extract. No FDA-recognized stan
Limited
Acerola Cherry
Enhanced vitamin C bioavailability vs isolated ascorbic acid
UCHIDA 2011 BIOAVAILABILITY: 50 mg vit C from acerola juice. COMMERCIAL: 100-500 mg p
Limited
Beef Kidney (Desiccated)
Exceptional selenium concentration
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef ki
Limited
Beef Liver (Desiccated)
Highest natural source of preformed vitamin A (retinol)
Typical supplementation: 3-6 g/day (4-8 capsules at 750 mg each) desiccated beef live
Limited
Beef Spleen (Desiccated)
Immune-related peptides (mechanistically interesting, clinically uncharacterized)
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef sp
Limited
Camu Camu
Superior antioxidant effect vs isolated vitamin C
RCT: 70 mL 100% camu juice daily (~1050 mg vit C) × 7 d. POWDER SUPPLEMENTS: 100-500
Limited
Faecalibacterium prausnitzii (Next-Generation Probiotic)
Anti-inflammatory effects in IBD
Clinical trial doses: typically 1-10 billion CFU/day in oxygen-protected formulations
Limited
Myrrh (Commiphora molmol)
Anti-inflammatory Activity (Mechanistic / Preclinical)
MIRAZID® antiparasitic: 600 mg (2 × 300 mg) daily empty stomach × 3-6 d. Soliman 2004
Limited
Oregano Oil (Origanum vulgare)
Enteric Parasite Activity (Limited Human Evidence)
FORCE 2000 ENTERIC PARASITES: 600 mg emulsified oregano oil daily × 6 wk. CONSUMER: 1
Limited
Sparassis crispa (Cauliflower Mushroom / Hanabiratake)
Highest β-glucan content (>40% dry weight)
β-GLUCAN content: >40% of dry weight (highest among medicinal mushrooms). MOUSE Sarco
Limited
Uva ursi (Bearberry)
Traditional use for acute urinary tract infection symptoms
ATAFUTI 2019: 3600 mg extract = 720 mg arbutin/day × 5 d. REGATTA: 6 caps × 105 mg =
Limited
Chaga Mushroom (Inonotus obliquus)
Immune Modulation
500-2,000 mg/day extract; standardized to beta-glucan content (typically 30%+); tradi
Limited
Eyebright (Euphrasia officinalis)
Conjunctivitis and eye irritation relief
Oral: 400–800 mg/day dried herb or standardized extract; ophthalmic solution: 1–2 dro
Limited
Immunell™ (Nucleotides + Prebiotic Acacia)
Immune Response Reinforcement
Nexira specifies recommended dose; clinical research uses varying nucleotide intake l
Limited
Iron Polysaccharide Complex (Niferex®)
Better GI Tolerability
150-300 mg elemental iron/day (Niferex® Forte = 150 mg elemental iron per capsule)
Limited
Isenolic® (Olive Polyphenols for Cold/Flu)
Immune Support
Per Pharmactive product specification
Limited
Cat's Claw (Uncaria tomentosa)
Immune system modulation
250–500 mg/day standardized POA extract; rheumatoid arthritis trials: 60 mg freeze-dr
Limited
CompleteGreens™ (Comprehensive Greens Base)
Immune and antioxidant support
3–8g/day comprehensive greens blend; specific CompleteGreens™ dosing per NNB product
Limited
Hōlistiq™ (Adaptogen + Mushroom Wellness Blend)
Immune modulation and defense
Per product label; typical adaptogen blend 300–800mg/day; mushroom component 500mg–2g
Preliminary
Noni (Morinda citrifolia)
Immune modulation
30–750 mL/day noni juice; most studies use 29–118 mL (1–4 oz) daily; freeze-dried pow