Home Ingredients Apigenius® (Apigenin)
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Apigenius® (Apigenin)

Evidence Level
Preliminary
0 Clinical Trials
3 Documented Benefits
1/5 Evidence Score

Apigenius® supplies apigenin, a flavonoid found in chamomile, parsley, and celery that is best known as the calming compound in chamomile tea. Apigenin is used in relaxation and sleep formulas, though human clinical evidence for the isolated compound is still limited and mostly preliminary.

Studied Dose Commonly around 50 mg per day, often before bed.
Active Compound Apigenin, a flavone (flavonoid) found in chamomile and other plants.

Benefits

Relaxation and sleep

Apigenin is the flavonoid linked to chamomile's long traditional use for calm and sleep, and is used in modern relaxation and sleep formulas.

Calm and stress support

Apigenin is studied for gently supporting a relaxed state, though most evidence is preliminary or from laboratory research.

Antioxidant support

As a flavonoid, apigenin provides antioxidant activity.

Mechanism of action

1

GABA receptor interaction

Apigenin is thought to interact with benzodiazepine and GABA-A receptor sites in the brain, a proposed basis for its mild calming effect.

2

Antioxidant and anti-inflammatory action

Apigenin scavenges free radicals and modulates inflammatory signaling in laboratory studies.

Clinical trials

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Sedatives or sleep medication — possible additive calming effect; use caution.
Tell your doctor if pregnant or breastfeeding.
Use caution if combining with other sleep aids.

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Frequently asked questions about Apigenius® (Apigenin)

What is Apigenius® (Apigenin)?

Apigenius® supplies apigenin, a flavonoid found in chamomile, parsley, and celery that is best known as the calming compound in chamomile tea. Apigenin is used in relaxation and sleep formulas, though human clinical evidence for the isolated compound is still limited and mostly preliminary.

What is the recommended dosage of Apigenius® (Apigenin)?

The clinically studied dose for Apigenius® (Apigenin) is Commonly around 50 mg per day, often before bed.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Apigenius® (Apigenin) used for?

Apigenius® (Apigenin) is studied for relaxation and sleep, calm and stress support, antioxidant support. Apigenin is the flavonoid linked to chamomile's long traditional use for calm and sleep, and is used in modern relaxation and sleep formulas.

Are there side effects from taking Apigenius® (Apigenin)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Apigenius® (Apigenin) safe to take?

Whether Apigenius® (Apigenin) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. It may also interact with certain medications. Apigenius® (Apigenin) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.