ZeaONE® (Natural Zeaxanthin from Marigold)

Tagetes erecta
Evidence Level
Very Strong
1 Clinical Trial
5 Documented Benefits
5/5 Evidence Score

ZeaONE® is the SOURCE OF NATURAL ZEAXANTHIN from marigold flowers manufactured by Kemin Industries — used in DSM's OPTISHARP™ Natural product. Distinguished by RR-zeaxanthin natural form (matching retinal tissue), marigold flower source aligned with FloraGLO® Lutein. The B2B/business positioning of the same natural zeaxanthin that's in OPTISHARP Natural retail products.

Studied Dose 2 mg/day natural zeaxanthin (typically combined with 10 mg lutein)
Active Compound RR-Zeaxanthin from Tagetes erecta marigold flowers

Benefits

Natural Zeaxanthin Source for Eye Health

ZeaONE provides the natural marigold-sourced zeaxanthin that's used in OPTISHARP Natural and Kemin's branded products. Same evidence base as OPTISHARP Natural.

AREDS2 Foundation

AREDS2 trial established lutein + zeaxanthin for AMD; ZeaONE provides natural zeaxanthin component.

Foveal Macular Pigment

Zeaxanthin specifically concentrates in central foveal region; ZeaONE supports foveal pigment density.

Combined with FloraGLO Lutein

Aligned source (both from marigolds); standard combination for comprehensive macular carotenoid support.

Sustainable Marigold Cultivation

Kemin's marigold supply chain provides sustainable natural zeaxanthin source.

Mechanism of action

1

Same as OPTISHARP Natural

ZeaONE is the natural zeaxanthin material used in DSM's OPTISHARP Natural; same mechanism of action — macular pigment, blue light filtering, antioxidant protection.

2

Natural RR-Zeaxanthin Form

Natural-source zeaxanthin from marigolds is RR-isomer matching retinal tissue.

3

Foveal Concentration

Zeaxanthin preferentially concentrates in foveal center where most acute vision occurs.

4

Marigold Source Alignment

Same source plant (Tagetes erecta) as FloraGLO Lutein — sustainable aligned supply chain.

Clinical trials

1
Same Evidence Base as OPTISHARP Natural
PubMed

ZeaONE evidence base derives from AREDS2 and other clinical trials of natural zeaxanthin.

AREDS2: 4,203 participants.

Reduced AMD progression with lutein + zeaxanthin supplementation.

About this ingredient

About the active ingredient

ZEAONE® is the SOURCE OF NATURAL ZEAXANTHIN from marigold flowers (Tagetes erecta) manufactured by KEMIN INDUSTRIES — used in DSM's OPTISHARP™ Natural product. RELATIONSHIP: ZeaONE is the B2B/business-side branded ingredient; OPTISHARP Natural is the consumer-facing branded version using ZeaONE; both refer to same natural marigold-sourced zeaxanthin in this Kemin-DSM partnership.

KEY DISTINCTIONS: same as OPTISHARP Natural — natural RR-zeaxanthin, marigold source, AREDS2 evidence base.

EVIDENCE-BASED USES: same as OPTISHARP Natural — AMD support, macular pigment density, blue light filtering, eye health.

CRITICAL CAUTIONS: (1) ZEAONE vs OPTISHARP NATURAL — same underlying natural zeaxanthin in different brand presentations; both Kemin-related; verify product brand for clinical evidence alignment; (2) DOSE — 2 mg/day natural zeaxanthin research-validated; typically combined with 10 mg lutein; (3) NATURAL vs SYNTHETIC — both ZeaONE and OPTISHARP Natural are NATURAL marigold-sourced zeaxanthin; some other zeaxanthin products use synthetic forms; verify natural source for AREDS2 alignment; (4) PREGNANCY/LACTATION — generally safe; (5) AREDS2 INDICATION — for intermediate AMD; (6) For COMPREHENSIVE EYE HEALTH — ZeaONE/OPTISHARP Natural component alongside lutein, zinc, antioxidant vitamins; (7) BRAND VERIFICATION — ZeaONE® is Kemin trademark; OPTISHARP™ Natural is DSM trademark; both reference same natural zeaxanthin material; this entry covers the Kemin-side ZeaONE branding for completeness.

Side effects and drug interactions

Common Potential side effects

Same as OPTISHARP Natural.
Generally extremely well-tolerated.
Mild GI distress (rare).
Yellowing of skin at very high doses.

Important Drug interactions

Same as OPTISHARP Natural / general zeaxanthin.
Generally minimal drug interactions.
Pregnancy/lactation — generally safe.
Children — safe.

Frequently asked questions about ZeaONE® (Natural Zeaxanthin from Marigold)

What is the recommended dosage of ZeaONE® (Natural Zeaxanthin from Marigold)?

The clinically studied dose for ZeaONE® (Natural Zeaxanthin from Marigold) is 2 mg/day natural zeaxanthin (typically combined with 10 mg lutein). Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is ZeaONE® (Natural Zeaxanthin from Marigold) used for?

ZeaONE® (Natural Zeaxanthin from Marigold) is studied for natural zeaxanthin source for eye health, areds2 foundation, foveal macular pigment. ZeaONE provides the natural marigold-sourced zeaxanthin that's used in OPTISHARP Natural and Kemin's branded products. Same evidence base as OPTISHARP Natural.

Are there side effects from taking ZeaONE® (Natural Zeaxanthin from Marigold)?

Reported potential side effects may include: Same as OPTISHARP Natural. Generally extremely well-tolerated. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Does ZeaONE® (Natural Zeaxanthin from Marigold) interact with medications?

Known drug interactions may include: Same as OPTISHARP Natural / general zeaxanthin. Generally minimal drug interactions. Consult a pharmacist or healthcare provider if you take prescription medications.

Is ZeaONE® (Natural Zeaxanthin from Marigold) good for eye health?

Yes, ZeaONE® (Natural Zeaxanthin from Marigold) is researched for Eye Health support. ZeaONE provides the natural marigold-sourced zeaxanthin that's used in OPTISHARP Natural and Kemin's branded products. Same evidence base as OPTISHARP Natural.