Top 5 — Ranked by Evidence
Very Strong
Vitamin A
Vision support
700–900 mcg RAE/day (adults); upper limit 3,000 mcg RAE/day
Very Strong
Vitamin D
Bone Health and Fracture Prevention
600–800 IU/day (RDA); optimal blood levels (50–80 ng/mL) typically require 2,000
Strong
Andrographis (ParActin®)
Cold and upper respiratory infection treatment
200–400 mg/day standardized extract (at 30% andrographolide); cold/flu treatment
Strong
Berberine
Blood Sugar Regulation
500–1,500 mg per day, often divided into 2–3 doses taken with meals to improve a
Strong
Beta-Glucans (Oat & Yeast-Derived)
Cholesterol and LDL reduction (FDA-approved claim)
3 g/day oat beta-glucan for FDA cholesterol health claim; immune modulation: 250
All Respiratory Health Ingredients (27)
Very Strong
Vitamin A
Vision support
700–900 mcg RAE/day (adults); upper limit 3,000 mcg RAE/day
Very Strong
Vitamin D
Bone Health and Fracture Prevention
600–800 IU/day (RDA); optimal blood levels (50–80 ng/mL) typically require 2,000
Strong
Andrographis (ParActin®)
Cold and upper respiratory infection treatment
200–400 mg/day standardized extract (at 30% andrographolide); cold/flu treatment
Strong
Berberine
Blood Sugar Regulation
500–1,500 mg per day, often divided into 2–3 doses taken with meals to improve a
Strong
Beta-Glucans (Oat & Yeast-Derived)
Cholesterol and LDL reduction (FDA-approved claim)
3 g/day oat beta-glucan for FDA cholesterol health claim; immune modulation: 250
Strong
Black Seed Oil / Thymoquinone (ThymoQuin®)
Immune system modulation and respiratory health
450–2,000 mg/day black seed oil; ThymoQuin® clinical doses: 450–900 mg/day; most
Strong
Boswellia Serrata (WokVel®)
Osteoarthritis and joint pain relief
100–250 mg/day high-AKBA extract (Aflapin® or 5-Loxin®); standard boswellia: 400
Strong
Manganese
Mitochondrial antioxidant defense via MnSOD
1.8–2.3 mg/day (AI for adults); upper limit 11 mg/day; most multivitamins contai
Strong
NAC (N-Acetylcysteine)
Antioxidant Support
600–1,800 mg/day in divided doses; respiratory: 600 mg twice daily; liver suppor
Strong
Olive Leaf Extract (Witholytin®)
Blood pressure reduction
500–1,000 mg/day standardized extract; EFSA cardiovascular claim dose: 5 mg/day
Moderate
AlvioLife® (Respiratory Health & Performance)
Easier breathing and airway support
Per AlvioLife® clinical dosing; PLT Health Solutions product specifications
Moderate
Astragalus (Astragalus membranaceus)
Immune system modulation and enhancement
9–30 g/day dried root (traditional TCM dose); standardized extract: 400–1,200 mg
Moderate
Bromelain
Anti-inflammatory and pain relief
200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals
Moderate
Butterbur (Petasites hybridus)
Migraine prevention
50–75 mg twice daily PA-free Petadolex® (75–150 mg/day) for migraine prevention;
Moderate
Colostrum
Immune Support
10-20g per day
Moderate
Echinacea
Immune System Support
300–500 mg three times daily (900–1,500 mg/day) during illness; prevention: 300
Moderate
Elderberry
Reduced cold and flu duration
600–900 mg extract/day during illness; 150–300 mg/day for prevention
Moderate
Goldenseal (Hydrastis canadensis)
Antimicrobial and immune support
500–1,000 mg/day dried root powder; standardized extract: 250–500 mg/day; typica
Moderate
Holy Basil (Tulsi)
Stress adaptation and cortisol regulation
300–600 mg/day dried leaf extract; 1–2 g/day whole leaf powder
Moderate
Licorice Root (Glycyrrhiza glabra)
Digestive and GI mucosal protection (DGL form)
DGL for GI: 380–760 mg chewable before meals; whole licorice: 200–600 mg/day (li
Moderate
MSM (Methylsulfonylmethane)
Joint Health and Arthritis Relief
1,000–3,000 mg/day elemental sulfur form; joint/anti-inflammatory: 1,500–3,000 m
Moderate
Metabolaid® (Hibiscus + Lemon Verbena)
AMPK activation and fat oxidation
500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before ex
Moderate
PROMUNEL® (Propolis Immune Extract)
Broad-spectrum antimicrobial and antiviral activity
400–800 mg/day propolis extract; PROMUNEL® clinical dose per PLT specifications;
Moderate
Shatavari (Asparagus racemosus / Xeya®)
Female hormonal balance and reproductive health
500–1,000 mg/day dried root extract; Xeya® clinical dose: 500 mg/day; lactation
Moderate
Shilajit / Fulvic Acid (PrimaVie®)
Testosterone and male reproductive health
250–500 mg/day purified shilajit or PrimaVie®; testosterone studies use 250 mg t
Limited
Chlorella
Heavy metal and toxin binding
3–10 g/day dried powder (tablets or powder); cracked cell wall preparation essen
Limited
Eyebright (Euphrasia officinalis)
Conjunctivitis and eye irritation relief
Oral: 400–800 mg/day dried herb or standardized extract; ophthalmic solution: 1–