Home Ingredients Appethyl® (Spinach Thylakoid Extract)
Weight Management

Appethyl® (Spinach Thylakoid Extract)

Spinacia oleracea
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Appethyl® is a concentrated spinach (Spinacia oleracea) thylakoid extract, the green chlorophyll-containing membranes of spinach leaves. Taken before meals, thylakoids slow fat digestion and boost satiety hormones, and are studied for reducing hunger and cravings to support weight management.

Studied Dose Around 5 grams taken before a meal.
Active Compound Concentrated spinach thylakoid membranes (chloroplast membrane fraction).

Benefits

Appetite and satiety

In a randomized controlled trial, spinach thylakoid extract reduced hunger, increased satiety, and reduced cravings for palatable food in overweight women.

Supported by Trial 1

Craving control

Thylakoids are studied for curbing the urge to snack on sweet and fatty foods, supporting adherence to a calorie-controlled diet.

Supported by Trial 1

Weight management

By extending fullness and reducing cravings, thylakoid extract supports gradual weight management.

Supported by Trial 1

Mechanism of action

1

Slowed fat digestion

Thylakoids slow the breakdown of dietary fat by lipase, which prolongs the presence of nutrients in the gut and the release of fullness signals.

2

Satiety-hormone release

Delayed digestion promotes release of satiety hormones such as GLP-1 and CCK while curbing hunger-driving ghrelin.

Clinical trials

1
Spinach Thylakoids and Satiety — RCT
PubMed

Randomized controlled trial of thylakoid-rich spinach extract on hunger, satiety, and cravings. (Stenblom et al. 2015, Appetite)

Overweight women.

Thylakoid extract reduced hunger and cravings and increased satiety versus control.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — digestive symptoms are most common.
Mild bloating or changes in stool can occur.
Take before meals with water.

Important Drug interactions

Fat-soluble vitamin absorption may be modestly affected; maintain a balanced diet.
Generally compatible with medications.
Tell your doctor if you manage blood sugar or take medication.

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Frequently asked questions about Appethyl® (Spinach Thylakoid Extract)

What is Appethyl® (Spinach Thylakoid Extract)?

Appethyl® is a concentrated spinach (Spinacia oleracea) thylakoid extract, the green chlorophyll-containing membranes of spinach leaves. Taken before meals, thylakoids slow fat digestion and boost satiety hormones, and are studied for reducing hunger and cravings to support weight management.

What is the recommended dosage of Appethyl® (Spinach Thylakoid Extract)?

The clinically studied dose for Appethyl® (Spinach Thylakoid Extract) is Around 5 grams taken before a meal.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Appethyl® (Spinach Thylakoid Extract) used for?

Appethyl® (Spinach Thylakoid Extract) is studied for appetite and satiety, craving control, weight management. In a randomized controlled trial, spinach thylakoid extract reduced hunger, increased satiety, and reduced cravings for palatable food in overweight women.

Are there side effects from taking Appethyl® (Spinach Thylakoid Extract)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — digestive symptoms are most common. Mild bloating or changes in stool can occur. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Appethyl® (Spinach Thylakoid Extract) safe to take?

Whether Appethyl® (Spinach Thylakoid Extract) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — digestive symptoms are most common. It may also interact with certain medications. Appethyl® (Spinach Thylakoid Extract) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Stenblom EL, Egecioglu E, Landin-Olsson M, et al. Consumption of thylakoid-rich spinach extract reduces hunger, increases satiety and reduces cravings for palatable food in overweight women. Appetite. 2015;91:209-19..PubMedUsed to support: RCT supporting appetite and satiety benefit of spinach thylakoids.