Benefits
Dental Health Support
BLIS M18 colonizes oral cavity and supports tooth health — produces bacteriocins targeting cariogenic bacteria including Streptococcus mutans (primary cavity-causing bacteria).
Gum Health Adjunct
Modulates oral microbiome supporting healthy gums; complementary to dental hygiene practices.
Plaque Reduction
Some BLIS M18 trials demonstrate reduced dental plaque accumulation.
Oral Microbiome Balance
Establishes beneficial Streptococcus salivarius population reducing pathogenic bacteria.
Streptococcus mutans Inhibition
Specifically targets S. mutans (primary cavity-causing organism) via salivaricin M production.
Adjunct to Dental Hygiene
Used in conjunction with regular brushing, flossing, dental visits — enhances rather than replaces traditional dental care.
Mechanism of action
Oral Cavity Colonization
S. salivarius M18 colonizes oral cavity competing with pathogenic bacteria for niches.
Salivaricin M Production
Produces salivaricin M — bacteriocin targeting S. mutans (primary cavity-causing bacteria).
Cariogenic Bacteria Inhibition
Reduces populations of S. mutans, S. sobrinus, and other cavity-causing bacteria.
Enzyme Production
Produces enzymes that may support oral cavity homeostasis.
Clinical trials
Multiple BLIS M18 RCTs on dental health markers including S. mutans counts, plaque, gum health.
Children and adults.
Reduced S. mutans counts; supports dental health markers.
About this ingredient
BLIS M18 is a PROPRIETARY STREPTOCOCCUS SALIVARIUS PROBIOTIC STRAIN developed by BLIS TECHNOLOGIES — distinguished from BLIS K12 by specific oral/dental health applications.
KEY DISTINCTIONS: (1) DENTAL HEALTH FOCUS (vs K12 ENT focus); (2) Targets S. MUTANS (cavity-causing); (3) Produces SALIVARICIN M; (4) Complementary to BLIS K12; (5) Dairy-free version available; (6) Distributed by Stratum Nutrition.
EVIDENCE-BASED USES: (1) Dental health; (2) Gum health adjunct; (3) Plaque reduction; (4) Oral microbiome balance; (5) Dental hygiene adjunct; (6) Cavity prevention support.
CRITICAL CAUTIONS: (1) ADJUNCT NOT REPLACEMENT — BLIS M18 supports dental hygiene; does NOT replace brushing, flossing, dental visits; (2) DAIRY ALLERGY — use dairy-free version; (3) IMMUNOCOMPROMISED — caution; consult; (4) ANTIBIOTICS — separate timing; (5) DOSE — 1 billion CFU/day; (6) DELIVERY FORMAT — lozenges or chewable for oral cavity colonization; (7) BLIS M18 vs BLIS K12 — M18 dental, K12 ENT; complementary; can be used together; (8) BLIS M18 vs DENTAL HYGIENE PRODUCTS — adjunct to traditional care; modulates microbiome differently than antimicrobial mouthwash; (9) FOR COMPREHENSIVE DENTAL HEALTH — twice-daily brushing, daily flossing, regular dental visits, balanced diet, BLIS M18 adjunct; (10) BRAND VERIFICATION — BLIS M18 is Blis Technologies trademark; specific patented strain.