Home Ingredients Bonolive® (Olive Leaf Oleuropein — BioActor)
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Bonolive® (Olive Leaf Oleuropein — BioActor)

Olea europaea
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Bonolive® is a standardized olive (Olea europaea) leaf extract from BioActor, concentrated for oleuropein, the main polyphenol in olive leaves. It is studied for supporting bone health in postmenopausal women and for joint function, drawing on oleuropein's antioxidant and bone-supportive actions.

Studied Dose About 250 mg per day, providing a standardized oleuropein dose.
Active Compound Olive leaf extract standardized to a high content of oleuropein, an antioxidant secoiridoid polyphenol.

Benefits

Bone health

Oleuropein-rich olive leaf extract is studied for supporting bone-forming activity and bone mineral density, particularly in postmenopausal women at risk of bone loss.

Supported by Trial 1

Joint function

In a clinical study, the oleuropein-based supplement supported joint functional capacity, easing everyday joint discomfort.

Supported by Trial 1

Antioxidant support

Oleuropein is a strong antioxidant that helps counter the oxidative stress involved in bone and joint aging.

Supported by Trial 1

Mechanism of action

1

Osteoblast support

Oleuropein promotes the activity of osteoblasts, the cells that build bone, while moderating bone-resorbing cells, favoring bone formation.

2

Anti-inflammatory polyphenol

By lowering inflammatory signaling and oxidative stress, oleuropein supports the health of bone and joint tissue.

Clinical trials

1
Oleuropein Supplement and Joint Function — Study
PubMed

Clinical study of an oleuropein-based olive leaf supplement on joint functional capacity. (Horcajada et al. 2022, Therapeutic Advances in Musculoskeletal Disease)

Adults with joint discomfort.

The oleuropein supplement supported improvements in joint functional capacity, consistent with its anti-inflammatory and tissue-supportive actions.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — olive leaf extract is well tolerated.
Mild digestive upset is occasionally reported.
Those allergic to olive should avoid it.

Important Drug interactions

Blood pressure medication — olive leaf may have a mild additive lowering effect; monitor.
Diabetes medication — may affect blood sugar; watch levels.
Tell your doctor if you take medication for bone density.

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Frequently asked questions about Bonolive® (Olive Leaf Oleuropein — BioActor)

What is Bonolive® (Olive Leaf Oleuropein — BioActor)?

Bonolive® is a standardized olive (Olea europaea) leaf extract from BioActor, concentrated for oleuropein, the main polyphenol in olive leaves. It is studied for supporting bone health in postmenopausal women and for joint function, drawing on oleuropein's antioxidant and bone-supportive actions.

What is the recommended dosage of Bonolive® (Olive Leaf Oleuropein — BioActor)?

The clinically studied dose for Bonolive® (Olive Leaf Oleuropein — BioActor) is About 250 mg per day, providing a standardized oleuropein dose.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Bonolive® (Olive Leaf Oleuropein — BioActor) used for?

Bonolive® (Olive Leaf Oleuropein — BioActor) is studied for bone health, joint function, antioxidant support. Oleuropein-rich olive leaf extract is studied for supporting bone-forming activity and bone mineral density, particularly in postmenopausal women at risk of bone loss.

Are there side effects from taking Bonolive® (Olive Leaf Oleuropein — BioActor)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — olive leaf extract is well tolerated. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Bonolive® (Olive Leaf Oleuropein — BioActor) safe to take?

Whether Bonolive® (Olive Leaf Oleuropein — BioActor) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — olive leaf extract is well tolerated. It may also interact with certain medications. Bonolive® (Olive Leaf Oleuropein — BioActor) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Horcajada MN, Beaumont M, Sauvageot N, et al. An oleuropein-based dietary supplement may improve joint functional capacity in older people with high knee joint pain. Ther Adv Musculoskelet Dis. 2022;14:1759720X211070205..PubMedUsed to support: Clinical study supporting joint functional benefit.