Home Ingredients Neuravena® (Wild Green Oat Extract — Frutarom)
Cognitive

Neuravena® (Wild Green Oat Extract — Frutarom)

Avena sativa
Evidence Level
Strong
2 Clinical Trials
6 Documented Benefits
4/5 Evidence Score

Neuravena® (EFLA® 955) is a PROPRIETARY WILD GREEN OAT EXTRACT (Avena sativa) developed by Frutarom Health (now IFF) — distinguished from generic oat extracts by use of WILD strain and bioactivity testing. Multiple clinical trials in cognitive function applications. Used for: cognitive function, attention, brain health, cognitive performance support across age groups. One of Frutarom Health's flagship branded ingredients.

Studied Dose 800-1,600 mg/day Neuravena (research-validated)
Active Compound Wild green oat (Avena sativa) standardized bioactivity-tested extract

Benefits

Cognitive Function and Attention

Multiple Neuravena trials demonstrated improvements in cognitive tasks including attention, executive function, processing speed in older and younger adults.

Supported by Trial 1

Cognitive Performance Under Demand

Some Neuravena trials show benefits in cognitive performance under cognitive load conditions.

Supported by Trial 1, Trial 2

Mental Performance for Working Adults

Frutarom positioning emphasizes mental performance for daily work demands across age groups.

Supported by Trial 1, Trial 2

Wild Strain Distinction

Neuravena uses specific wild oat strain (vs commercial oat varieties) selected for higher bioactive content.

Supported by Trial 1, Trial 2

Bioactivity Testing

Frutarom's bioactivity testing distinguishes Neuravena from generic oat extracts; ensures clinical reproducibility.

Supported by Trial 1, Trial 2

Mediterranean Diet Heritage

Wild oat traditionally consumed in some Mediterranean populations; modern research validates cognitive applications.

Supported by Trial 1, Trial 2

Mechanism of action

1

Phosphodiesterase 4 (PDE4) Inhibition

Wild oat compounds modestly inhibit PDE4 — increases cAMP signaling in neurons; mechanism for cognitive effects.

2

Monoamine Oxidase B (MAO-B) Inhibition

Modest MAO-B inhibition supports dopamine signaling — relevant to cognitive function and motivation.

3

Cerebral Blood Flow Effects

Some evidence for improved cerebral blood flow contributing to cognitive effects.

4

Antioxidant Activity

Wild oat polyphenols provide neuronal antioxidant protection.

Clinical trials

1
Neuravena for Cognitive Function — Multiple RCTs
PubMed

Multiple Neuravena RCTs on cognitive function across age groups including older adults.

Various adult populations.

Improvements in cognitive tasks including attention, executive function. Five published peer-reviewed clinical trials.

2
Neuravena for Cognitive Performance — Acute Effects
PubMed

Studies of Neuravena acute cognitive effects.

Healthy adults.

Cognitive performance improvements within hours of supplementation.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress.
Allergic reactions to oats — relevant for those with celiac disease (oats often cross-contaminated with wheat) or gluten sensitivity.
Theoretical effects on iron absorption (oat phytates).

Important Drug interactions

MAOIs — theoretical interaction with MAO-B inhibitor mechanism.
Levothyroxine — fiber may modestly affect; separate timing.
Antidepressants — theoretical interactions.
Pregnancy — generally considered safe.
Lactation — generally safe.
Celiac disease / gluten sensitivity — verify oat purity.

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Frequently asked questions about Neuravena® (Wild Green Oat Extract — Frutarom)

What is the recommended dosage of Neuravena® (Wild Green Oat Extract — Frutarom)?

The clinically studied dose for Neuravena® (Wild Green Oat Extract — Frutarom) is 800-1,600 mg/day Neuravena (research-validated). Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Neuravena® (Wild Green Oat Extract — Frutarom) used for?

Neuravena® (Wild Green Oat Extract — Frutarom) is studied for cognitive function and attention, cognitive performance under demand, mental performance for working adults. Multiple Neuravena trials demonstrated improvements in cognitive tasks including attention, executive function, processing speed in older and younger adults.

Are there side effects from taking Neuravena® (Wild Green Oat Extract — Frutarom)?

Reported potential side effects may include: Generally well-tolerated. Mild GI distress. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Does Neuravena® (Wild Green Oat Extract — Frutarom) interact with medications?

Known drug interactions may include: MAOIs — theoretical interaction with MAO-B inhibitor mechanism. Levothyroxine — fiber may modestly affect; separate timing. Consult a pharmacist or healthcare provider if you take prescription medications.

Is Neuravena® (Wild Green Oat Extract — Frutarom) good for cognitive?

Yes, Neuravena® (Wild Green Oat Extract — Frutarom) is researched for Cognitive support. Multiple Neuravena trials demonstrated improvements in cognitive tasks including attention, executive function, processing speed in older and younger adults.