Benefits
Cognitive Function and Attention
Multiple Neuravena trials demonstrated improvements in cognitive tasks including attention, executive function, processing speed in older and younger adults.
Cognitive Performance Under Demand
Some Neuravena trials show benefits in cognitive performance under cognitive load conditions.
Mental Performance for Working Adults
Frutarom positioning emphasizes mental performance for daily work demands across age groups.
Wild Strain Distinction
Neuravena uses specific wild oat strain (vs commercial oat varieties) selected for higher bioactive content.
Bioactivity Testing
Frutarom's bioactivity testing distinguishes Neuravena from generic oat extracts; ensures clinical reproducibility.
Mediterranean Diet Heritage
Wild oat traditionally consumed in some Mediterranean populations; modern research validates cognitive applications.
Mechanism of action
Phosphodiesterase 4 (PDE4) Inhibition
Wild oat compounds modestly inhibit PDE4 — increases cAMP signaling in neurons; mechanism for cognitive effects.
Monoamine Oxidase B (MAO-B) Inhibition
Modest MAO-B inhibition supports dopamine signaling — relevant to cognitive function and motivation.
Cerebral Blood Flow Effects
Some evidence for improved cerebral blood flow contributing to cognitive effects.
Antioxidant Activity
Wild oat polyphenols provide neuronal antioxidant protection.
Clinical trials
Multiple Neuravena RCTs on cognitive function across age groups including older adults.
Various adult populations.
Improvements in cognitive tasks including attention, executive function. Five published peer-reviewed clinical trials.
Studies of Neuravena acute cognitive effects.
Healthy adults.
Cognitive performance improvements within hours of supplementation.
About this ingredient
NEURAVENA® (EFLA® 955) is a PROPRIETARY WILD GREEN OAT EXTRACT (AVENA SATIVA) developed by FRUTAROM HEALTH (now IFF). WILD GREEN OAT BACKGROUND: harvested at GREEN STAGE (before grain ripening) when bioactive content is highest; WILD STRAIN selected for higher bioactivity vs commercial varieties; distinct from common oat (Avena sativa cultivated grain).
KEY DISTINCTIONS: (1) WILD STRAIN vs commercial; (2) GREEN STAGE harvest; (3) BIOACTIVITY TESTING — Frutarom distinguishing process; (4) Five published peer-reviewed clinical trials; (5) Frutarom Health quality.
EVIDENCE-BASED USES: (1) Cognitive function and attention; (2) Cognitive performance under cognitive demand; (3) Mental performance for working adults; (4) Cognitive aging support.
CRITICAL CAUTIONS: (1) DOSE — 800-1,600 mg/day Neuravena; (2) DURATION — cognitive effects build over weeks; some acute effects also documented; (3) CELIAC DISEASE — oats themselves are gluten-free but commonly cross-contaminated with wheat; verify product purity for celiac users; (4) PREGNANCY/LACTATION — generally considered safe; (5) NEURAVENA vs OTHER COGNITIVE INGREDIENTS — different mechanisms vs Bacopin (cholinergic), Neumentix (rosmarinic acid), L-theanine (alpha brain waves), Cognivia (sage); complementary; (6) NEURAVENA vs GENERIC OAT — wild strain + bioactivity testing distinguishes; generic oat extracts not equivalent; (7) BRAND VERIFICATION — Neuravena® and EFLA® are Frutarom/IFF trademarks; specific clinical evidence on this branded form; (8) FRUTAROM EFLA LINE — broader Frutarom Health portfolio includes Neuravena, Portusana, AB-Fortis, CitrOlive; (9) For COMPREHENSIVE COGNITIVE HEALTH — exercise, sleep, social engagement, learning, supplements adjunct; (10) Among Frutarom Health's flagship US-market branded ingredients.