Benefits
Cardiometabolic support
Pine bark OPCs are studied for supporting healthy blood pressure, blood-vessel function, and cardiometabolic markers.
Antioxidant defense
The procyanidins are potent antioxidants that protect blood vessels and tissues from oxidative stress.
Circulation
By supporting nitric oxide and endothelial function, pine bark extract is used to support healthy circulation.
Mechanism of action
Endothelial nitric oxide
OPCs support nitric oxide production in blood-vessel linings, promoting vasodilation and healthy blood flow.
Antioxidant polyphenols
The low-molecular-weight procyanidins are readily absorbed and scavenge free radicals throughout the vasculature.
Clinical trials
Study of supplementation with pine bark extract on cardiometabolic measures. (Mohammadi et al. 2025, BMC Complementary Medicine and Therapies)
Adults.
Pine bark extract supplementation supported cardiometabolic markers, consistent with the antioxidant and vascular actions of its procyanidins.