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Top Picks — Anti-Inflammatory

🔥 Best Anti-Inflammatory Supplements

Curcumin, Boswellia, Omega-3, and clinically-validated anti-inflammatory ingredients for chronic inflammation, joint pain, and inflammatory marker reduction.

137 ingredients reviewed Ranked by clinical evidence

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Top 5 — Ranked by Evidence

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used

Anti-Inflammatory and Immune Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

ThymoQuin® (Black Seed Oil — TriNutra)

Anti-inflammatory effects

Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty

BioTurmin® (Bioavailable Turmeric)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Anti-inflammatory and pain relief

200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d

📈 Fastest Growing Anti-Inflammatory Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)

144× Bioavailability vs Standard Curcumin

250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)

CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)

45.5× Free Curcuminoid Bioavailability

400-500 mg/day CurQfen (research-validated; some applications use higher)

PEA — Palmitoylethanolamide

Allergic and inflammatory conditions

300-1,200 mg/day; commonly 600 mg twice daily (1,200 mg total); bioavailable forms (Levagen+®)…

🔬 Future Anti-Inflammatory Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day (often 250 mg twice daily).

Tart Cherry Extract

Anti-inflammatory effects

Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day,…

Upper respiratory tract infections

200-1,200 mg/day of extract standardized to >=10% andrographolides, used short term at the…

Recommended Anti-Inflammatory Products

Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.

Real products featuring the best-evidenced anti-inflammatory ingredients ranked above — chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.

Best foundational anti-inflammatory Amazon →

Nordic Naturals Ultimate Omega

EPA + DHA fish oil — 1280 mg per serving

Omega-3s are the most evidence-backed supplement for reducing inflammatory markers — multiple clinical trials show lower hs-CRP, IL-6, and TNF-α at 2-4 g/day EPA+DHA. Works by shifting cell membrane composition away from pro-inflammatory omega-6 eicosanoids. Nordic Naturals delivers 1280 mg EPA+DHA per serving and publishes a Certificate of Analysis for every batch.

Best botanical anti-inflammatory (Meriva®) Amazon →

Thorne Curcumin Phytosome (Meriva®)

Meriva® curcumin phytosome — 1000 mg

Meriva® has the most clinical trials of any curcumin form for inflammation reduction — 29x better absorption than plain curcumin via Indena's phytosome technology (curcumin + phosphatidylcholine). Direct evidence for hs-CRP reduction and joint inflammation. Works via COX-2 inhibition and NF-κB pathway modulation — different mechanism than omega-3s, so they stack well.

Best for 5-LOX pathway inflammation Amazon →

Pure Encapsulations Boswellia AKBA (5-LOXIN®)

5-LOXIN® Boswellia extract — 30% AKBA

Boswellia AKBA inhibits the 5-LOX inflammation pathway — a different mechanism than curcumin's COX-2 inhibition, which means they work synergistically rather than redundantly. 5-LOXIN® has 10x more AKBA (the most active boswellic acid) than typical Boswellia extracts. Strongest evidence for joint and arthritis-related inflammation.

Best NRF2 activator / cellular antioxidant defense Amazon →

Avmacol Extra Strength Sulforaphane

Glucoraphanin + active myrosinase enzyme

Avmacol is the #1 sulforaphane-producing supplement used in human clinical trials (Johns Hopkins and others). Sulforaphane is the most potent natural NRF2 activator known — works upstream by triggering the body's master antioxidant response (glutathione production, phase II detox enzymes). The Extra Strength version includes active myrosinase enzyme — critical because without it, the broccoli seed glucoraphanin can't convert to sulforaphane in your gut.

All Anti-Inflammatory Ingredients (144)

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used

Anti-Inflammatory and Immune Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

ThymoQuin® (Black Seed Oil — TriNutra)

Anti-inflammatory effects

Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty

BioTurmin® (Bioavailable Turmeric)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Anti-inflammatory and pain relief

200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d

CurcuZen® (Curcumin Extract)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Boswellia Serrata

Anti-inflammatory and antioxidant

Standard dose: 300-1,200 mg/day standardized boswellia extract. Joint applications: 1

EssentiOmega® (Omega-3 Concentrate)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Ginger (Zingiber officinale)

Anti-inflammatory and lipid effects

250–2,000 mg/day dried ginger powder or standardized extract; nausea: 1–1.5 g/day; an

Olive Leaf Extract

Antioxidant and anti-inflammatory effects

Standard dose: 500-1,000 mg/day standardized olive leaf extract (containing 20-40% ol

PEA — Palmitoylethanolamide

Allergic and inflammatory conditions

Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,2

Anti-Inflammatory Effects

500–1,000 mg/day; absorption enhanced significantly with vitamin C or bromelain; quer

Aronia / Chokeberry (Aronia melanocarpa)

Possible Anti-Inflammatory Effects

STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day

Curcumin/Turmeric

Anti-Inflammatory Effects

RAW POWDER: 500-2000 mg/day = 60-100 mg curcumin. STANDARDIZED 95% curcuminoids: 400-

Serrapeptase (Serratiopeptidase)

Sinusitis and Upper Respiratory Inflammation

10-60 mg/day (typically 10-30 mg/day), standardized to 20,000-80,000 enzymatic units;

Ahiflower® (Buglossoides Plant Omegas — Stratum Nutrition)

GLA Content for Inflammation

1-3 g/day Ahiflower oil

Levagen+® (PEA — Palmitoylethanolamide — Gencor)

Anti-inflammatory effects

Standard dose: 300-600 mg/day Levagen+® — substantially lower than typical PEA protoc

ParActin® (Andrographis Extract — HP Ingredients)

No inflammation biomarker data in the cited studies

Standard formulation use: 100-300 mg ParActin® once or twice daily. Take with food to

Anti-inflammatory effects

150–500 mg/day trans-resveratrol; bioavailability enhanced with piperine or liposomal

Anti-Inflammatory Effects

250-1,000 mg/day; often combined with vitamin C and other bioflavonoids

Spectra® (30-plant antioxidant blend — FutureCeuticals)

Helps maintain a healthy inflammatory response

100 mg single oral dose (capsule) in the published human crossover studies

Antioxidant and Anti-inflammatory Effects

500–3,000 mg/day; energy drinks typically contain 1,000 mg; athletic performance: 1–3

Curcumin C3 Reduct® (Tetrahydrocurcuminoids — Sabinsa)

Anti-inflammatory support

Commonly around 150 to 600 mg per day.

AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)

Balanced inflammation

Around 100 to 250 mg of the standardized extract per day.

Cinnamon (Ceylon vs Cassia)

Anti-Inflammatory / Antioxidant

1-6 g/day cinnamon powder; 250-500 mg/day water-soluble extract (Cinnulin PF® standar

Dry N-3® (Powdered Omega-3)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Elantria® Algal DHA (Vegan Omega-3 DHA)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

GingerWarmer® (Ginger Extract)

Anti-inflammatory and joint support

Commonly around 1 gram of ginger per day.

Ginginoll® (Ginger Extract — Akay)

Anti-inflammatory support

Commonly around 1 gram of ginger per day.

GOPO® Rosehip (Hyben Vital — Rosa canina)

GOPO galactolipid anti-inflammatory mechanism

5 g/day rosehip powder (typically split as 2.5 g twice daily). Onset of pain relief:

Limonene (D-Limonene)

Anti-inflammatory effects (in elderly individuals)

GERD (Wilkins 2002 + Sun 2007): 1000 mg orally daily or QOD. CANCER PHASE I/II: 0.5-1

Phellodendron (Huang Bai)

Anti-inflammatory and antimicrobial effects (TCM traditional + mechanistic)

RELORA® (Phellodendron + Magnolia): 250 mg × 3/day = 750 mg/day. PHELLODENDRON ALONE

Rosehip (Rosa canina)

Effect on inflammatory markers is unproven

STANDARD: 5 g/day rosehip powder (Hyben Vital® / LitoZin®) split 2-3 doses with meals

V-Krill Omega® (Krill Omega-3)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Anti-inflammatory effect

RCT: 70 mL 100% camu juice daily (~1050 mg vit C) × 7 d. POWDER SUPPLEMENTS: 100-500

Promentum® (calcium fructoborate for joint comfort, FutureCeuticals)

Helps maintain a healthy inflammatory balance

108 mg twice daily (216 mg/day); some trials used 110-220 mg/day, or 216 mg once daily

VitaCherry® Sport (whole tart cherry recovery powder — FutureCeuticals)

Promotes a healthy inflammatory and antioxidant response

Marketed at roughly 400 mg/day; class evidence used ~480 mg tart-cherry powder or ~30 mL Montmorency concentrate/day

Burdock Root (Arctium lappa)

Knee Osteoarthritis Inflammation Reduction

MAGHSOUMI-NOROUZABAD 2016 OA: 3 cups burdock tea daily (each 2 g root in 150 mL boile

Molecular Hydrogen (H2)

Inflammation markers (one trial, not replicated)

HRW: 1.5-7 ppm H2 in water, 0.5-2 L/day. LeBaron 2020 high-conc: ~7 ppm × 24 wk metab

Betalains (Beetroot Pigments)

Inflammatory markers unchanged in betalain trials

BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI

Cat's Claw (Uncaria tomentosa)

Anti-inflammatory and antioxidant activity

250–500 mg/day standardized POA extract; rheumatoid arthritis trials: 60 mg freeze-dr

Clostridium butyricum MIYAIRI 588 (CBM588 / MIYA-BM® / Butirrisan®)

Inflammatory bowel disease: no evidence cited here

Standard dose: 20-80 mg/day of MIYA-BM® powder providing 1-4×10⁸ CFU. Adult AAD preve

Curcumin C3 Complex® (Most Studied Curcumin Extract)

Anti-inflammatory pathways, shown mostly in the laboratory

500–1,000 mg/day curcumin C3 Complex® (standardized to 95% curcuminoids); combine wit

DurOmega® (Stabilized Omega-3)

Inflammation: not measured in the cited research

Commonly 1 to 3 g of combined EPA and DHA per day.

Reduced inflammatory markers

Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do

Japanese Knotweed (Polygonum cuspidatum)

Anti-inflammatory effects (small basketball player trial)

STANDARDIZED EXTRACTS (8% trans-resveratrol): 250-500 mg 1-2×/day → 20-40 mg resverat

Rosmarinic Acid

Anti-inflammatory activity seen in laboratory studies

ALLERGIC RHINITIS: 50-200 mg/day Perilla × 21 d. AD COGNITION (Noguchi-Shinohara): 50

Tart Cherry Extract

Anti-inflammatory effects

Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times

Theracurmin® (Colloidal Nanoparticle Curcumin — Theravalues)

Immune and inflammatory measures: studied, but results not detailed

Theracurmin®: 30-180 mg/day (provides curcumin equivalent of much higher standard cur

AKBAMax® / BosPure® (Boswellia serrata Standardized to AKBA — Arjuna)

Anti-inflammatory support

Around 100 to 250 mg per day of the standardized extract.

General Anti-Inflammatory Activity

LAKHAN/KIRBY 2014 HASHIMOTO: 9-24 mg/day × 3 mo lozenges + vit A + D3. Former Anatabl

Attenutin® (Scutellaria and Acacia for Respiratory Health — Unigen)

Immune and inflammatory balance

Per the product specification.

Bifidobacterium infantis 35624 (Align® / Bifantis® / Meta Align®)

Immune and cytokine signals, mostly from studies outside IBS

PIVOTAL: 100 million CFU/day (1×10⁸) — narrow window, both 1 million and 10 billion C

BioPure DHA® (Tuna Oil Omega-3 DHA)

Lower C-reactive protein

Commonly 1 to 3 g of combined EPA and DHA per day.

CavaCurmin® (Curcumin Gamma-Cyclodextrin — Wacker)

Anti-inflammatory support

About 500 mg of the complex per day; the bioavailability study compared standardized

Curcumax (Turmeric, Ginger & Black Pepper Blend)

Inflammation — not measured in people

Commonly 500 mg per day of the bioavailable formulation.

CuroWhite® (Hydrogenated Curcuminoids — Aurea)

Antioxidant and anti-inflammatory

Around 300 to 500 mg per day.

Feverfew (Tanacetum parthenium)

Anti-inflammatory activity

50–300 mg/day dried leaf (standardized to ≥0.2% parthenolide); MIG-99: 6.25 mg three

Reduced post-surgical edema and inflammation

Digestive: 100,000–200,000 USP units per meal; Systemic anti-inflammatory: 200–400 mg

Tenzara™ (Curcumin + Boswellia FenuMat® Synergy — Akay Bioactives)

Multi-pathway anti-inflammatory mechanism

400 mg/day Tenzara once daily (Mamatha 2025 clinical trial protocol). The 24.8× free

Verilla® (Perilla Extract for Seasonal Allergy)

Anti-inflammatory support

Around 50 to 200 mg of rosmarinic acid per day.

Anti-inflammatory effects (mechanism-based)

TOPICAL CREAM: 2×/day × 3 mo. ORAL D. ALATA: 2 sachets/day = 12 mg phytosterol × 12 m

Anti-inflammatory Activity

NO STANDARDIZED CLINICAL DOSE. DIETARY: 5-10 mg/day Western, up to 50+ mg/day high-ve

Meriva® (Curcumin Phytosome by Indena)

Absorption: About 29 Times Higher Than Unformulated Curcuminoids

1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail

Anti-inflammatory effects (preclinical, strawberry RCTs)

DIETARY: ~30-50 mg glycosides per 150 g strawberries. STRAWBERRY RCTs: 250-500 g fres

Tributyrin (CoreBiome® Butyrate Prodrug)

Microbiome and inflammation effects (in vitro)

SHIME® IN VITRO: 300 mg cap + 450 mg softgel. FSU CrossOver: 300 mg/day × 4 wk (TERMI

AprèsFlex® / Aflapin® (Boswellia AKBA — Laila Nutraceuticals)

Markers of inflammation in the blood

Standard dose: 100 mg twice daily (200 mg/day total) AprèsFlex®/Aflapin®. Onset of ef

Brox-25® (Bromelain)

Inflammation and swelling

Commonly 200 to 500 mg (or defined enzyme-activity units) per day.

Arnica (Arnica montana)

Post-surgical pain and swelling — formulation matters

TOPICAL (recommended): 20% tincture or 10-25% gel 2-4×/day. OTC: Arnicare®, Traumeel®

Faecalibacterium prausnitzii (Next-Generation Probiotic)

Anti-inflammatory effects in IBD

Clinical trial doses: typically 1-10 billion CFU/day in oxygen-protected formulations

Kutki (Picrorhiza kurroa)

Anti-inflammatory effects (animal and laboratory studies)

TRADITIONAL AYURVEDIC: 250-500 mg dried rhizome 2-3×/day OR 1-3 g/day decoction. STAN

Antioxidant and anti-inflammatory

DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1

Myrrh (Commiphora molmol)

Anti-inflammatory Activity (Mechanistic / Preclinical)

MIRAZID® antiparasitic: 600 mg (2 × 300 mg) daily empty stomach × 3-6 d. Soliman 2004

Protease (Proteolytic Enzymes)

Chronic inflammatory and circulatory conditions

Digestive: 30,000–60,000 HUT with meals; Systemic anti-inflammatory: Wobenzym® 3 tabl

Wormwood (Artemisia absinthium)

Anti-Inflammatory and Antioxidant Effects

OMER 2007 Crohn's herbal blend: 3 × 500 mg/day × 10 wk. Krebs 2010: SedaCrohn® × 6 wk

Guggul (Commiphora mukul)

Possible Anti-Inflammatory Activity

INDIAN RCTs: 50 mg guggulipid (~3.5 mg guggulsterones) BID × 12-24 wk. WESTERN: 1000-

Punarnava (Boerhavia diffusa)

Anti-inflammatory and antioxidant activity in laboratory and animal studies

TRADITIONAL: 1-3 g whole plant powder OR 250-500 mg standardized extract 2-3×/day. Pu

Thymocid® (Black Cumin Seed Extract — Natural Remedies)

Anti-inflammatory support

A standardized daily dose providing a defined amount of thymoquinone.

Xorialyc® (Olive Leaf Extract for Skin Inflammation)

Inflammatory Pathway Effects Seen in Cell Cultures

300 mg/day (research-validated dose)

Calendula (Pot Marigold)

Anti-inflammatory and antimicrobial activity (laboratory and animal models)

RADIATION DERMATITIS: Boiron Pommade au Calendula 2×/day during radiotherapy. WOUND/S

Poria cocos / Wolfiporia cocos (Fu Ling / Hoelen / Tuckahoe)

Anti-swelling triterpenes in mice (animal data only)

INSOMNIA: 800 mg ethanol extract nightly (21-adult polysomnography study). SLEEP COMB

Anti-inflammatory and antioxidant effects (modest)

MUSCLE/STRENGTH: 400-450 mg/day divided (Bang 2014: 450 mg POSITIVE; Pereira 2020: 40

Bakuchi (Bakuchiol)

Antioxidant and anti-inflammatory mechanisms

TOPICAL: 0.5-1.0% bakuchiol cream 1-2×/day (Dhaliwal 2019: 0.5% × 12 wk = retinol-equ

Chrysin (5,7-Dihydroxyflavone)

Anti-inflammatory and antioxidant (mechanistic)

CRITICAL: poor oral bioavailability (<1%) — most marketed doses mechanistically irrel

Honokiol (Magnolia officinalis Bark)

Inflammation markers in cell studies only

Purified honokiol: 250 mg 1-2 times daily. Relora® (magnolia + phellodendron combinat

NaturSYN® Defense (Rye and Oyster Mushroom Blend)

Inflammatory mediators: laboratory testing only

Per the product specification.

NovaSOL® Curcumin (Liquid Micellar Curcumin — Aquanova)

Inflammation: not measured in this product's study

Often a low dose of curcuminoids per day, since absorption is much higher than standa

Boswellin® / Boswellin® Super (Standardized Boswellia serrata — Sabinsa)

Knee osteoarthritis — pain, stiffness, function

Boswellin® Super: 100-300 mg twice daily (200-600 mg/day). The Majeed 2024 dose-findi

Chronic venous insufficiency symptom reduction

Standard dose: 900 mg diosmin + 100 mg hesperidin (1,000 mg MPFF total) once or twice

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

LDL oxidation protection (EU-authorized health claim)

5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol

IBS symptom improvement

IBS (enteric-coated peppermint oil): 180-225 mg L-menthol equivalent 3×/day (IBgard®)

Omega-3 Fatty Acids

Triglyceride reduction

1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (

5-Loxin® (Boswellia AKBA — PLT/OmniActive)

Studied in people with knee osteoarthritis

100 to 250 mg once daily. Knee osteoarthritis trials used 100 mg/day and 250 mg/day o

Upper respiratory tract infections

Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% androgr

AstaPure® (Natural Astaxanthin — Algatech)

Antioxidant and recovery support

4 to 12 mg per day, taken with a fat-containing meal for absorption.

Eye health and visual function

4–12 mg/day from Haematococcus pluvialis extract; skin: 4–6 mg/day; exercise recovery

Diabetic peripheral neuropathy (mixed RCT results)

DIABETIC NEUROPATHY (BENDIP): 600 mg/day × 6 wk then 300 mg/day. BOND: 300 mg BID × 1

Butcher's Broom (Ruscus aculeatus)

Leg comfort and healthy vein tone (studied in venous insufficiency)

VANSCHEIDT 2002 PROTOCOL: 36-37.5 mg extract = 7-11 mg ruscogenins/day. ESCP guidelin

Capsaicin / Capsicum Extract (Cayenne Pepper)

Thermogenic energy expenditure (class evidence)

Class-effective doses across human trials: 2-10 mg total capsaicinoids per day (2 mg/

Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)

144× Bioavailability vs Standard Curcumin

250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)

CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)

45.5× Free Curcuminoid Bioavailability

400-500 mg/day CurQfen (research-validated; some applications use higher)

Metabolic syndrome — multiple markers improve together

METABOLIC SYNDROME (Hidalgo-Lozada 2022): 500 mg BID = 1000 mg/day pomegranate 90% EA

Evening Primrose Oil (Oenothera biennis)

Eczema and atopic dermatitis improvement

3–6 g/day EPO (providing 240–480 mg GLA); eczema: 4–8 g/day; PMS: 3–4 g/day; diabetic

Longvida® Optimized Curcumin (Verdure Sciences)

Cognitive Function (400 mg/day)

400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco

Neem (Azadirachta indica)

Plaque and Gingivitis Reduction (RCT-Confirmed)

PINGALI 2020 T2DM: 125/250/500 mg standardized neem BID = 250-1000 mg/day × 12 wk + m

Oligopin® (French Maritime Pine Bark Extract — DRT)

Cardiometabolic support

Around 100 to 150 mg per day.

Pine Bark Extract

Cardiovascular support

Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)

Pomegranate Extract

Blood pressure and arterial health

Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3

Punicalagins (Pomegranate Polyphenols)

Modest blood pressure reduction

POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED

Pycnogenol® (French Maritime Pine Bark)

Blood pressure — modest effect, mostly in hypertensives

50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor

Modest support for healthy blood pressure in people with elevated readings (meta-analysis)

BP: 60 mg/day × 4 wk hypertensive. LIPID: 200-247 mg/day (Wu 2006: 50 g/d seed). 20-H

Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)

What the cited human studies actually measured

Standard formulation use: 30-150 mg Truebroc® daily (providing 4-20 mg glucoraphanin)

Witholytin® (Olive Leaf Extract — Verdure Sciences)

Reduced fatigue and low energy

Clinical trial protocol: 500 mg twice daily (1,000 mg/day total) for 8 weeks. Mainten

Yüth® (Spermidine)

Autophagy induction and cellular rejuvenation

1–10 mg/day spermidine (Yüth® formulation specifications); typical supplement use: 1.

Neuropathic Pain Reduction

PAIN TRIALS: 1.335-3.560 g/day. RCT: 2.670 g/day divided × 14 d. BODYBUILDING: 500 mg

Almega®PL (Microalgae EPA Omega-3 — Qualitas)

Vegan EPA omega-3

A serving providing roughly 250 mg or more of EPA per day.

Antrodia cinnamomea (Niu-Chang-Chih / Stout Camphor Fungus)

NASH 6-month RCT

NASH RCT: 3 capsules/day = 420 mg ACM × 6 months (n=28). SUBHEALTH ALT RCT: 250 mg AC

Ayuflex® (Terminalia chebula Extract — Natreon)

Joint comfort and function

250 to 500 mg per day. The clinical trial used 250 mg twice daily.

BioPerine® (Black Pepper Extract — Sabinsa)

The curcumin figure: widely quoted, not cited here

Standard formulation use: 5-10 mg BioPerine® per dose alongside compounds requiring a

GliSODin® (Vegetal SOD with Gliadin — Isocell)

Antioxidant blood markers in a 19-person athlete trial

Around 250 mg per day.

HydroCurc® (Highly Bioavailable Curcumin)

Enhanced Bioavailability vs Standard Curcumin

500 mg/day; clinical trials use 250-1,000 mg/day depending on indication

Sebum regulation in oily skin (topical, industry-sponsored)

TOPICAL: 100% pure jojoba 1-2×/day, OR 5-10% in cosmetics. CLAY+JOJOBA MASK: 2-3×/wee

Mast Cell Stabilization

100-300 mg/day general use; mast cell protocols often use luteolin 100-200 mg with qu

MicrobiomeX® (Citrus Flavonoid Extract — BioActor)

Shifts gut fatty acids toward butyrate

500 mg/day (studied 250-500 mg)

Mythocondro® (Non-Animal Chondroitin Sulfate — Gnosis by Lesaffre)

Joint comfort and function in a single 60-subject pilot RCT (600 mg/day)

PIVOTAL: 600 mg/day × 12 weeks (n=60 overweight knee OA). Notably lower than typical

Oregano Oil (Origanum vulgare)

Enteric Parasite Activity (Limited Human Evidence)

FORCE 2000 ENTERIC PARASITES: 600 mg emulsified oregano oil daily × 6 wk. CONSUMER: 1

Oxxynea® (Fruit and Vegetable Polyphenols — Fytexia)

Antioxidant intake

A standardized daily polyphenol dose equivalent to several servings of produce.

Pomella® (Pomegranate Extract — Verdure Sciences)

Cardiovascular rationale (pomegranate class, not Pomella-specific trials)

Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos

Sparassis crispa (Cauliflower Mushroom / Hanabiratake)

Highest β-glucan content (>40% dry weight)

β-GLUCAN content: >40% of dry weight (highest among medicinal mushrooms). MOUSE Sarco

Thyme (Thymus vulgaris)

Acute Bronchitis Cough Reduction (Thyme-Ivy Combination)

BRONCHIPRET® THYME-IVY: 5.4 mL × 3/day × 11 d. BRONCHIPRET® TP: 1 tablet × 3/day × 11

TurmiPure Gold® (Bioavailable Turmeric — Naturex)

Higher Curcuminoid Absorption Per Milligram

Per Naturex/Givaudan TurmiPure Gold product specification

Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)

A registered trial in people receiving chemotherapy for multiple myeloma (no results cited)

ANDOSAN™ ORAL: 60 mL/day liquid extract × 7 weeks (multiple myeloma protocol). NSCLC

Auricularia auricula-judae (Wood Ear / Black Jelly Mushroom)

Anticoagulant polysaccharide antithrombin-mediated

EDIBLE WOOD EAR: dietary consumption common in Asian cuisine — supports general food-

Danshen (Salvia miltiorrhiza)

Cardiovascular use in TCM and Chinese hospital practice

ORAL ROOT: 9-15 g dried decoction OR 1-3 g powdered. STANDARDIZED: 500-1500 mg 2-3×/d

Glycyrrhizina (Licorice Flavonoids — BGG)

The H. pylori figure is not supported here

Per BGG product specification

Phellinus linteus (Meshimakobu / Sanghuang)

Immune markers in a 30-person pilot trial (trend-level results)

: PL mycelium extract 1,000 mg/day × 8 weeks (n=98, KCTC0399BP strain). IMMUNITY RCT:

Pyritinol (Pyrithioxine / Encephabol)

What the dementia trial actually tested

Dementia (European Rx protocol): 200 mg hydrochloride three times daily (600 mg/day).