Top 5 — Ranked by Evidence
Very Strong
Omega-3 Fatty Acids
Rheumatoid arthritis — joint pain and stiffness
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Osteoarthritis pain — meaningful joint relief
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Very Strong
Longvida® Optimized Curcumin (Verdure Sciences)
Cognitive Function (400 mg/day)
400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco
Very Strong
Meriva® (Curcumin Phytosome — Indena)
Anti-Inflammatory Across Conditions
1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail
📈 Fastest Growing Anti-Inflammatory Ingredients
Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.
Trending
Very Strong
Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)
144× Bioavailability vs Standard Curcumin
250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)
Trending
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Trending
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,200 mg…
🔬 Future Anti-Inflammatory Ingredients to Watch
Lower current evidence but active research underway — these may become top picks within 2–3 years.
Watch
Strong
Casperome® (Boswellia Phytosome — Indena)
~3-4× improved boswellic acid bioavailability
250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used in the…
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Strong
Tart Cherry Extract
Post-exercise muscle recovery and reduced soreness
Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times daily…
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Strong
Andrographis
Upper respiratory tract infections
Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% andrographolides…
All Anti-Inflammatory Ingredients (110)
Very Strong
Omega-3 Fatty Acids
Rheumatoid arthritis — joint pain and stiffness
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Osteoarthritis pain — meaningful joint relief
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Very Strong
Longvida® Optimized Curcumin (Verdure Sciences)
Cognitive Function (400 mg/day)
400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco
Very Strong
Meriva® (Curcumin Phytosome — Indena)
Anti-Inflammatory Across Conditions
1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail
Very Strong
Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)
144× Bioavailability vs Standard Curcumin
250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)
Strong
Green Tea
Anti-Inflammatory and Immune Support
250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg
Strong
Clostridium butyricum MIYAIRI 588 (CBM588 / MIYA-BM® / Butirrisan®)
Inflammatory bowel disease support
Standard dose: 20-80 mg/day of MIYA-BM® powder providing 1-4×10⁸ CFU. Adult AAD preve
Strong
Ginger (Zingiber officinale)
Osteoarthritis pain — modest effect
250–2,000 mg/day dried ginger powder or standardized extract; nausea: 1–1.5 g/day; an
Strong
Pomegranate Extract
Blood pressure and arterial health
Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3
Strong
Diosmin
Chronic venous insufficiency symptom reduction
Standard dose: 900 mg diosmin + 100 mg hesperidin (1,000 mg MPFF total) once or twice
Strong
Pine Bark Extract
Cardiovascular support
Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)
Strong
BioPerine® (Black Pepper Extract — Sabinsa)
Documented curcumin bioavailability enhancement
Standard formulation use: 5-10 mg BioPerine® per dose alongside compounds requiring a
Strong
Boswellia Serrata
Osteoarthritis pain and function (Cochrane-level evidence)
Standard dose: 300-1,200 mg/day standardized boswellia extract. Joint applications: 1
Strong
Calendula (Pot Marigold)
Anti-inflammatory and mild antimicrobial topical use
RADIATION DERMATITIS: Boiron Pommade au Calendula 2×/day during radiotherapy. WOUND/S
Strong
Capsaicin / Capsicum Extract (Capsimax®)
Analgesic and anti-inflammatory effects
100–200 mg/day Capsimax® (2% capsaicinoids = 2–4 mg active capsaicinoids); timing: 30
Strong
Escherichia coli Nissle 1917 (Mutaflor®)
Anti-inflammatory gut effects
Ulcerative colitis maintenance: 100 mg twice daily (5×10⁹ CFU/capsule × 2/day) per Mu
Strong
Levagen+® (PEA — Palmitoylethanolamide — Gencor)
Pain reduction at lower doses
Standard dose: 300-600 mg/day Levagen+® — substantially lower than typical PEA protoc
Strong
Menthol
Topical analgesia for muscle and joint pain
IBS (enteric-coated peppermint oil): 180-225 mg L-menthol equivalent 3×/day (IBgard®)
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,2
Strong
ParActin® (Andrographis Extract — HP Ingredients)
Anti-inflammatory biomarker effects
Standard formulation use: 100-300 mg ParActin® once or twice daily. Take with food to
Strong
Pomella® (Pomegranate Extract — Verdure Sciences)
Standardized punicalagin delivery
Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos
Strong
Sulforaphane / Glucoraphanin
NRF2 activation (master antioxidant response)
Standard supplementation: 60-150 mg glucoraphanin with active myrosinase (provides 10
Strong
Tart Cherry Extract
Anti-inflammatory effects
Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times
Strong
Tea Tree Oil
Mild-to-moderate acne treatment
TOPICAL ACNE: 5% TTO gel 1-2×/day. DANDRUFF: 5% shampoo daily. ORAL/PERIODONTITIS: 0.
Strong
ThymoQuin® (Black Seed Oil — TriNutra)
Anti-inflammatory effects
Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty
Strong
Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)
Standardized glucoraphanin delivery
Standard formulation use: 30-150 mg Truebroc® daily (providing 4-20 mg glucoraphanin)
Strong
Witholytin® (Olive Leaf Extract — Verdure Sciences)
Blood pressure reduction in clinical trials
Clinical trial protocol: 500 mg twice daily (1,000 mg/day total) for 8 weeks. Mainten
Strong
WokVel® (Boswellia Serrata Extract — Pharmanza)
Osteoarthritis pain and function trials
Standard joint protocol: 333 mg three times daily (1,000 mg/day total) or equivalent
Strong
Ahiflower® (Buglossoides Plant Omegas — Stratum Nutrition)
GLA Content for Inflammation
1-3 g/day Ahiflower oil
Strong
Andrographis
Inflammatory bowel disease support
Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% androgr
Strong
Boswellin® / Boswellin® Super (Standardized Boswellia serrata — Sabinsa)
Knee osteoarthritis — pain, stiffness, function
Boswellin® Super: 100-300 mg twice daily (200-600 mg/day). The Majeed 2024 dose-findi
Strong
Casperome® (Boswellia Phytosome — Indena)
Joint and exercise-induced inflammation
250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used
Strong
HydroCurc® (Highly Bioavailable Curcumin)
Joint Health and Anti-Inflammatory Effects
500 mg/day; clinical trials use 250-1,000 mg/day depending on indication
Strong
Olive Leaf Extract
Antioxidant and anti-inflammatory effects
Standard dose: 500-1,000 mg/day standardized olive leaf extract (containing 20-40% ol
Strong
Tenzara™ (Curcumin + Boswellia FenuMat® Synergy — Akay Bioactives)
Pain and stiffness reduction in spondylitis (Mamatha 2025)
400 mg/day Tenzara once daily (Mamatha 2025 clinical trial protocol). The 24.8× free
Strong
Curcumin C3 Complex® (Most Studied Curcumin Extract)
Anti-inflammatory activity across 80+ studies
500–1,000 mg/day curcumin C3 Complex® (standardized to 95% curcuminoids); combine wit
Strong
Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)
LDL oxidation protection (EU-authorized health claim)
5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol
Strong
TurmiPure Gold® (Bioavailable Turmeric — Naturex)
Anti-Inflammatory Activity
Per Naturex/Givaudan TurmiPure Gold product specification
Moderate
Quercetin
Anti-Inflammatory Effects
500–1,000 mg/day; absorption enhanced significantly with vitamin C or bromelain; quer
Moderate
Taurine
Antioxidant and Anti-inflammatory Effects
500–3,000 mg/day; energy drinks typically contain 1,000 mg; athletic performance: 1–3
Moderate
Curcumin/Turmeric
Anti-Inflammatory Effects
RAW POWDER: 500-2000 mg/day = 60-100 mg curcumin. STANDARDIZED 95% curcuminoids: 400-
Moderate
Astaxanthin
Eye Health Benefits
4–12 mg/day from Haematococcus pluvialis extract; skin: 4–6 mg/day; exercise recovery
Moderate
MSM (Methylsulfonylmethane)
Osteoarthritis pain and function
Standard dose: 1.5-3 g/day, often split as 1 g twice daily. Joint applications: 3-6 g
Moderate
Neem (Azadirachta indica)
Plaque and Gingivitis Reduction (RCT-Confirmed)
PINGALI 2020 T2DM: 125/250/500 mg standardized neem BID = 250-1000 mg/day × 12 wk + m
Moderate
Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)
IBD cytokine modulation (Førland 2011)
ANDOSAN™ ORAL: 60 mL/day liquid extract × 7 weeks (multiple myeloma protocol). NSCLC
Moderate
Antrodia cinnamomea (Niu-Chang-Chih / Stout Camphor Fungus)
NASH 6-month RCT
NASH RCT: 3 capsules/day = 420 mg ACM × 6 months (n=28). SUBHEALTH ALT RCT: 250 mg AC
Moderate
AprèsFlex® / Aflapin® (Boswellia AKBA — Laila Nutraceuticals)
Osteoarthritis pain and function improvement
Standard dose: 100 mg twice daily (200 mg/day total) AprèsFlex®/Aflapin®. Onset of ef
Moderate
Aronia / Chokeberry (Aronia melanocarpa)
Possible Anti-Inflammatory Effects
STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day
Moderate
Bakuchi (Bakuchiol)
Antioxidant and anti-inflammatory mechanisms
TOPICAL: 0.5-1.0% bakuchiol cream 1-2×/day (Dhaliwal 2019: 0.5% × 12 wk = retinol-equ
Moderate
Benfotiamine
Diabetic peripheral neuropathy (mixed RCT results)
DIABETIC NEUROPATHY (BENDIP): 600 mg/day × 6 wk then 300 mg/day. BOND: 300 mg BID × 1
Moderate
Betalains (Beetroot Pigments)
Anti-inflammatory effects
BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI
Moderate
Bifidobacterium infantis 35624 (Align® / Bifantis® / Meta Align®)
Inflammatory cytokine modulation (gut-immune mechanism)
PIVOTAL: 100 million CFU/day (1×10⁸) — narrow window, both 1 million and 10 billion C
Moderate
Butcher's Broom (Ruscus aculeatus)
Symptomatic relief: heavy/tired legs, leg pain, tension
VANSCHEIDT 2002 PROTOCOL: 36-37.5 mg extract = 7-11 mg ruscogenins/day. ESCP guidelin
Moderate
Ellagic Acid
Metabolic syndrome — multiple markers improve together
METABOLIC SYNDROME (Hidalgo-Lozada 2022): 500 mg BID = 1000 mg/day pomegranate 90% EA
Moderate
Ferulic Acid
Reduced inflammatory markers
Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do
Moderate
GOPO® Rosehip (Hyben Vital — Rosa canina)
Hip and knee osteoarthritis pain relief
5 g/day rosehip powder (typically split as 2.5 g twice daily). Onset of pain relief:
Moderate
Jojoba Oil
Acne reduction (clay+jojoba mask, observational)
TOPICAL: 100% pure jojoba 1-2×/day, OR 5-10% in cosmetics. CLAY+JOJOBA MASK: 2-3×/wee
Moderate
Kutki (Picrorhiza kurroa)
Anti-inflammatory effects
TRADITIONAL AYURVEDIC: 250-500 mg dried rhizome 2-3×/day OR 1-3 g/day decoction. STAN
Moderate
Limonene (D-Limonene)
Anti-inflammatory effects (in elderly individuals)
GERD (Wilkins 2002 + Sun 2007): 1000 mg orally daily or QOD. CANCER PHASE I/II: 0.5-1
Moderate
Molecular Hydrogen (H2)
Anti-inflammatory effects (multiple conditions)
HRW: 1.5-7 ppm H2 in water, 0.5-2 L/day. LeBaron 2020 high-conc: ~7 ppm × 24 wk metab
Moderate
Mythocondro® (Non-Animal Chondroitin Sulfate — Gnosis by Lesaffre)
Knee OA improvement at 600 mg/day (pilot RCT)
PIVOTAL: 600 mg/day × 12 weeks (n=60 overweight knee OA). Notably lower than typical
Moderate
Phellinus linteus (Meshimakobu / Sanghuang)
Immune improvement RCT (, LDH cytotoxicity)
: PL mycelium extract 1,000 mg/day × 8 weeks (n=98, KCTC0399BP strain). IMMUNITY RCT:
Moderate
Phellodendron (Huang Bai)
Anti-inflammatory and antimicrobial effects (TCM traditional + mechanistic)
RELORA® (Phellodendron + Magnolia): 250 mg × 3/day = 750 mg/day. PHELLODENDRON ALONE
Moderate
Poria cocos / Wolfiporia cocos (Fu Ling / Hoelen / Tuckahoe)
Insomnia 21-adult polysomnography study (800 mg)
INSOMNIA: 800 mg ethanol extract nightly (21-adult polysomnography study). SLEEP COMB
Moderate
Protease (Proteolytic Enzymes)
Chronic inflammatory and circulatory conditions
Digestive: 30,000–60,000 HUT with meals; Systemic anti-inflammatory: Wobenzym® 3 tabl
Moderate
Punicalagins (Pomegranate Polyphenols)
Modest blood pressure reduction
POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED
Moderate
Resveratrol
Anti-inflammatory effects
150–500 mg/day trans-resveratrol; bioavailability enhanced with piperine or liposomal
Moderate
Rosehip (Rosa canina)
Reduced osteoarthritis pain (meta-analysis evidence)
STANDARD: 5 g/day rosehip powder (Hyben Vital® / LitoZin®) split 2-3 doses with meals
Moderate
Rosmarinic Acid
Anti-inflammatory effects via NF-κB inhibition
ALLERGIC RHINITIS: 50-200 mg/day Perilla × 21 d. AD COGNITION (Noguchi-Shinohara): 50
Moderate
Sesamin
Modest blood pressure reduction in hypertension (meta-analysis)
BP: 60 mg/day × 4 wk hypertensive. LIPID: 200-247 mg/day (Wu 2006: 50 g/d seed). 20-H
Moderate
Theracurmin® (Colloidal Nanoparticle Curcumin — Theravalues)
Osteoarthritis pain reduction
Theracurmin®: 30-180 mg/day (provides curcumin equivalent of much higher standard cur
Moderate
Yüth® (Spermidine)
Autophagy induction and cellular rejuvenation
1–10 mg/day spermidine (Yüth® formulation specifications); typical supplement use: 1.
Moderate
Bromelain
Anti-inflammatory and pain relief
200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d
Moderate
Cinnamon (Ceylon vs Cassia)
Anti-Inflammatory / Antioxidant
1-6 g/day cinnamon powder; 250-500 mg/day water-soluble extract (Cinnulin PF® standar
Moderate
Evening Primrose Oil (Oenothera biennis)
Eczema and atopic dermatitis improvement
3–6 g/day EPO (providing 240–480 mg GLA); eczema: 4–8 g/day; PMS: 3–4 g/day; diabetic
Moderate
Papain
Pharyngitis (sore throat) and oral inflammation
Digestive: 100,000–200,000 USP units per meal; Systemic anti-inflammatory: 200–400 mg
Moderate
Rutin
Anti-Inflammatory Effects
250-1,000 mg/day; often combined with vitamin C and other bioflavonoids
Moderate
Thyme (Thymus vulgaris)
Acute Bronchitis Cough Reduction (RCT-Confirmed)
BRONCHIPRET® THYME-IVY: 5.4 mL × 3/day × 11 d. BRONCHIPRET® TP: 1 tablet × 3/day × 11
Moderate
Xorialyc® (Olive Leaf Extract for Skin Inflammation)
Multiple Inflammatory Pathway Inhibition
300 mg/day (research-validated dose)
Moderate
Calanus® Oil (Arctic Zooplankton Omega-3 Wax Esters)
Cardiovascular and heart function improvement
2g/day Calanus® Oil capsules; clinical study: 2–4g/day; wax ester form may have diffe
Moderate
Glycyrrhizina (Licorice Flavonoids — BGG)
Anti-Inflammatory Skin Effects
Per BGG product specification
Limited
Guggul (Commiphora mukul)
Possible Anti-Inflammatory Activity
INDIAN RCTs: 50 mg guggulipid (~3.5 mg guggulsterones) BID × 12-24 wk. WESTERN: 1000-
Limited
Agmatine
Neuropathic Pain Reduction
PAIN TRIALS: 1.335-3.560 g/day. RCT: 2.670 g/day divided × 14 d. BODYBUILDING: 500 mg
Limited
Arnica (Arnica montana)
Post-surgical pain and swelling — formulation matters
TOPICAL (recommended): 20% tincture or 10-25% gel 2-4×/day. OTC: Arnicare®, Traumeel®
Limited
Auricularia auricula-judae (Wood Ear / Black Jelly Mushroom)
Anticoagulant polysaccharide antithrombin-mediated
EDIBLE WOOD EAR: dietary consumption common in Asian cuisine — supports general food-
Limited
Camu Camu
Anti-inflammatory effect
RCT: 70 mL 100% camu juice daily (~1050 mg vit C) × 7 d. POWDER SUPPLEMENTS: 100-500
Limited
Danshen (Salvia miltiorrhiza)
Cardiovascular use in TCM and Chinese hospital practice
ORAL ROOT: 9-15 g dried decoction OR 1-3 g powdered. STANDARDIZED: 500-1500 mg 2-3×/d
Limited
Faecalibacterium prausnitzii (Next-Generation Probiotic)
Anti-inflammatory effects in IBD
Clinical trial doses: typically 1-10 billion CFU/day in oxygen-protected formulations
Limited
Honokiol (Magnolia officinalis Bark)
Anti-inflammatory effects (preclinical)
Purified honokiol: 250 mg 1-2 times daily. Relora® (magnolia + phellodendron combinat
Limited
Japanese Knotweed (Polygonum cuspidatum)
Anti-inflammatory effects (small basketball player trial)
STANDARDIZED EXTRACTS (8% trans-resveratrol): 250-500 mg 1-2×/day → 20-40 mg resverat
Limited
Kaempferol
Anti-inflammatory Activity
NO STANDARDIZED CLINICAL DOSE. DIETARY: 5-10 mg/day Western, up to 50+ mg/day high-ve
Limited
Myricetin
Antioxidant and anti-inflammatory
DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1
Limited
Myrrh (Commiphora molmol)
Anti-inflammatory Activity (Mechanistic / Preclinical)
MIRAZID® antiparasitic: 600 mg (2 × 300 mg) daily empty stomach × 3-6 d. Soliman 2004
Limited
Oregano Oil (Origanum vulgare)
Enteric Parasite Activity (Limited Human Evidence)
FORCE 2000 ENTERIC PARASITES: 600 mg emulsified oregano oil daily × 6 wk. CONSUMER: 1
Limited
Pelargonidin
Anti-inflammatory effects (preclinical, strawberry RCTs)
DIETARY: ~30-50 mg glycosides per 150 g strawberries. STRAWBERRY RCTs: 250-500 g fres
Limited
Punarnava (Boerhavia diffusa)
Anti-inflammatory and antioxidant activities
TRADITIONAL: 1-3 g whole plant powder OR 250-500 mg standardized extract 2-3×/day. Pu
Limited
Pyritinol (Pyrithioxine / Encephabol)
Senile dementia cognitive support
Dementia (European Rx protocol): 200 mg hydrochloride three times daily (600 mg/day).
Limited
Sparassis crispa (Cauliflower Mushroom / Hanabiratake)
Highest β-glucan content (>40% dry weight)
β-GLUCAN content: >40% of dry weight (highest among medicinal mushrooms). MOUSE Sarco
Limited
Tributyrin (CoreBiome® Butyrate Prodrug)
Microbiome and inflammation effects (in vitro)
SHIME® IN VITRO: 300 mg cap + 450 mg softgel. FSU CrossOver: 300 mg/day × 4 wk (TERMI
Limited
Ursolic Acid
Anti-inflammatory and antioxidant effects (modest)
MUSCLE/STRENGTH: 400-450 mg/day divided (Bang 2014: 450 mg POSITIVE; Pereira 2020: 40
Limited
Wild Yam
Anti-inflammatory effects (mechanism-based)
TOPICAL CREAM: 2×/day × 3 mo. ORAL D. ALATA: 2 sachets/day = 12 mg phytosterol × 12 m
Limited
Wormwood (Artemisia absinthium)
Anti-Inflammatory and Antioxidant Effects
OMER 2007 Crohn's herbal blend: 3 × 500 mg/day × 10 wk. Krebs 2010: SedaCrohn® × 6 wk
Limited
Anatabine
General Anti-Inflammatory Activity
LAKHAN/KIRBY 2014 HASHIMOTO: 9-24 mg/day × 3 mo lozenges + vit A + D3. Former Anatabl
Limited
Burdock Root (Arctium lappa)
Knee Osteoarthritis Inflammation Reduction
MAGHSOUMI-NOROUZABAD 2016 OA: 3 cups burdock tea daily (each 2 g root in 150 mL boile
Limited
Luteolin
Neuroinflammation Reduction
100-300 mg/day general use; mast cell protocols often use luteolin 100-200 mg with qu
Limited
Serrapeptase (Serratiopeptidase)
Sinusitis and Upper Respiratory Inflammation
10-60 mg/day (typically 10-30 mg/day), standardized to 20,000-80,000 enzymatic units;
Limited
Cat's Claw (Uncaria tomentosa)
Anti-inflammatory and antioxidant activity
250–500 mg/day standardized POA extract; rheumatoid arthritis trials: 60 mg freeze-dr
Limited
Feverfew (Tanacetum parthenium)
Anti-inflammatory activity
50–300 mg/day dried leaf (standardized to ≥0.2% parthenolide); MIG-99: 6.25 mg three
Preliminary
Chrysin (5,7-Dihydroxyflavone)
Anti-inflammatory and antioxidant (mechanistic)
CRITICAL: poor oral bioavailability (<1%) — most marketed doses mechanistically irrel