Top 5 — Ranked by Evidence
Very Strong
Omega-3 Fatty Acids
Rheumatoid arthritis — joint pain and stiffness
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Osteoarthritis pain — meaningful joint relief
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Very Strong
Longvida® Optimized Curcumin (Verdure Sciences)
Cognitive Function (400 mg/day)
400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco
Very Strong
Meriva® (Curcumin Phytosome — Indena)
Anti-Inflammatory Across Conditions
1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail
📈 Fastest Growing Anti-Inflammatory Ingredients
Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.
Trending
Very Strong
Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)
144× Bioavailability vs Standard Curcumin
250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)
Trending
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Trending
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,200 mg…
🔬 Future Anti-Inflammatory Ingredients to Watch
Lower current evidence but active research underway — these may become top picks within 2–3 years.
Watch
Strong
Casperome® (Boswellia Phytosome — Indena)
~3-4× improved boswellic acid bioavailability
250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used in the…
Watch
Strong
Tart Cherry Extract
Post-exercise muscle recovery and reduced soreness
Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times daily…
Watch
Strong
Andrographis
Upper respiratory tract infections
Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% andrographolides…
Recommended Anti-Inflammatory Products
Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.
Real products featuring the best-evidenced anti-inflammatory ingredients ranked above — chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.
Best foundational anti-inflammatory
Amazon →
Nordic Naturals Ultimate Omega
EPA + DHA fish oil — 1280 mg per serving
Omega-3s are the most evidence-backed supplement for reducing inflammatory markers — multiple clinical trials show lower hs-CRP, IL-6, and TNF-α at 2-4 g/day EPA+DHA. Works by shifting cell membrane composition away from pro-inflammatory omega-6 eicosanoids. Nordic Naturals delivers 1280 mg EPA+DHA per serving and publishes a Certificate of Analysis for every batch.
Best botanical anti-inflammatory (Meriva®)
Amazon →
Thorne Curcumin Phytosome (Meriva®)
Meriva® curcumin phytosome — 1000 mg
Meriva® has the most clinical trials of any curcumin form for inflammation reduction — 29x better absorption than plain curcumin via Indena's phytosome technology (curcumin + phosphatidylcholine). Direct evidence for hs-CRP reduction and joint inflammation. Works via COX-2 inhibition and NF-κB pathway modulation — different mechanism than omega-3s, so they stack well.
Best for 5-LOX pathway inflammation
Amazon →
Pure Encapsulations Boswellia AKBA (5-LOXIN®)
5-LOXIN® Boswellia extract — 30% AKBA
Boswellia AKBA inhibits the 5-LOX inflammation pathway — a different mechanism than curcumin's COX-2 inhibition, which means they work synergistically rather than redundantly. 5-LOXIN® has 10x more AKBA (the most active boswellic acid) than typical Boswellia extracts. Strongest evidence for joint and arthritis-related inflammation.
Best NRF2 activator / cellular antioxidant defense
Amazon →
Avmacol Extra Strength Sulforaphane
Glucoraphanin + active myrosinase enzyme
Avmacol is the #1 sulforaphane-producing supplement used in human clinical trials (Johns Hopkins and others). Sulforaphane is the most potent natural NRF2 activator known — works upstream by triggering the body's master antioxidant response (glutathione production, phase II detox enzymes). The Extra Strength version includes active myrosinase enzyme — critical because without it, the broccoli seed glucoraphanin can't convert to sulforaphane in your gut.
All Anti-Inflammatory Ingredients (141)
Very Strong
Omega-3 Fatty Acids
Rheumatoid arthritis — joint pain and stiffness
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Osteoarthritis pain — meaningful joint relief
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor
Very Strong
CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)
45.5× Free Curcuminoid Bioavailability
400-500 mg/day CurQfen (research-validated; some applications use higher)
Very Strong
Longvida® Optimized Curcumin (Verdure Sciences)
Cognitive Function (400 mg/day)
400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco
Very Strong
Meriva® (Curcumin Phytosome — Indena)
Anti-Inflammatory Across Conditions
1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail
Very Strong
Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)
144× Bioavailability vs Standard Curcumin
250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)
Strong
Green Tea
Anti-Inflammatory and Immune Support
250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg
Strong
Clostridium butyricum MIYAIRI 588 (CBM588 / MIYA-BM® / Butirrisan®)
Inflammatory bowel disease support
Standard dose: 20-80 mg/day of MIYA-BM® powder providing 1-4×10⁸ CFU. Adult AAD preve
Strong
Ginger (Zingiber officinale)
Osteoarthritis pain — modest effect
250–2,000 mg/day dried ginger powder or standardized extract; nausea: 1–1.5 g/day; an
Strong
Pomegranate Extract
Blood pressure and arterial health
Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3
Strong
Diosmin
Chronic venous insufficiency symptom reduction
Standard dose: 900 mg diosmin + 100 mg hesperidin (1,000 mg MPFF total) once or twice
Strong
Pine Bark Extract
Cardiovascular support
Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)
Strong
BioPerine® (Black Pepper Extract — Sabinsa)
Documented curcumin bioavailability enhancement
Standard formulation use: 5-10 mg BioPerine® per dose alongside compounds requiring a
Strong
Boswellia Serrata
Osteoarthritis pain and function (Cochrane-level evidence)
Standard dose: 300-1,200 mg/day standardized boswellia extract. Joint applications: 1
Strong
Calendula (Pot Marigold)
Anti-inflammatory and mild antimicrobial topical use
RADIATION DERMATITIS: Boiron Pommade au Calendula 2×/day during radiotherapy. WOUND/S
Strong
Escherichia coli Nissle 1917 (Mutaflor®)
Anti-inflammatory gut effects
Ulcerative colitis maintenance: 100 mg twice daily (5×10⁹ CFU/capsule × 2/day) per Mu
Strong
Levagen+® (PEA — Palmitoylethanolamide — Gencor)
Pain reduction at lower doses
Standard dose: 300-600 mg/day Levagen+® — substantially lower than typical PEA protoc
Strong
Menthol
Topical analgesia for muscle and joint pain
IBS (enteric-coated peppermint oil): 180-225 mg L-menthol equivalent 3×/day (IBgard®)
Strong
PEA — Palmitoylethanolamide
Neuropathic pain relief (substantial evidence)
Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,2
Strong
ParActin® (Andrographis Extract — HP Ingredients)
Anti-inflammatory biomarker effects
Standard formulation use: 100-300 mg ParActin® once or twice daily. Take with food to
Strong
Pomella® (Pomegranate Extract — Verdure Sciences)
Standardized punicalagin delivery
Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos
Strong
Sulforaphane / Glucoraphanin
NRF2 activation (master antioxidant response)
Standard supplementation: 60-150 mg glucoraphanin with active myrosinase (provides 10
Strong
Tart Cherry Extract
Anti-inflammatory effects
Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times
Strong
Tea Tree Oil
Mild-to-moderate acne treatment
TOPICAL ACNE: 5% TTO gel 1-2×/day. DANDRUFF: 5% shampoo daily. ORAL/PERIODONTITIS: 0.
Strong
ThymoQuin® (Black Seed Oil — TriNutra)
Anti-inflammatory effects
Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty
Strong
Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)
Standardized glucoraphanin delivery
Standard formulation use: 30-150 mg Truebroc® daily (providing 4-20 mg glucoraphanin)
Strong
Witholytin® (Olive Leaf Extract — Verdure Sciences)
Blood pressure reduction in clinical trials
Clinical trial protocol: 500 mg twice daily (1,000 mg/day total) for 8 weeks. Mainten
Strong
WokVel® (Boswellia Serrata Extract — Pharmanza)
Osteoarthritis pain and function trials
Standard joint protocol: 333 mg three times daily (1,000 mg/day total) or equivalent
Strong
Ahiflower® (Buglossoides Plant Omegas — Stratum Nutrition)
GLA Content for Inflammation
1-3 g/day Ahiflower oil
Strong
Andrographis
Inflammatory bowel disease support
Standard URI dose: 200-1,200 mg/day andrographis extract standardized to ≥10% androgr
Strong
Boswellin® / Boswellin® Super (Standardized Boswellia serrata — Sabinsa)
Knee osteoarthritis — pain, stiffness, function
Boswellin® Super: 100-300 mg twice daily (200-600 mg/day). The Majeed 2024 dose-findi
Strong
Capsaicin / Capsicum Extract (Cayenne Pepper)
Thermogenic energy expenditure (class evidence)
Class-effective doses across human trials: 2-10 mg total capsaicinoids per day (2 mg/
Strong
Casperome® (Boswellia Phytosome — Indena)
Joint and exercise-induced inflammation
250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used
Strong
HydroCurc® (Highly Bioavailable Curcumin)
Joint Health and Anti-Inflammatory Effects
500 mg/day; clinical trials use 250-1,000 mg/day depending on indication
Strong
Olive Leaf Extract
Antioxidant and anti-inflammatory effects
Standard dose: 500-1,000 mg/day standardized olive leaf extract (containing 20-40% ol
Strong
Tenzara™ (Curcumin + Boswellia FenuMat® Synergy — Akay Bioactives)
Pain and stiffness reduction in spondylitis (Mamatha 2025)
400 mg/day Tenzara once daily (Mamatha 2025 clinical trial protocol). The 24.8× free
Strong
Curcumin C3 Complex® (Most Studied Curcumin Extract)
Anti-inflammatory activity across 80+ studies
500–1,000 mg/day curcumin C3 Complex® (standardized to 95% curcuminoids); combine wit
Strong
Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)
LDL oxidation protection (EU-authorized health claim)
5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol
Strong
TurmiPure Gold® (Bioavailable Turmeric — Naturex)
Anti-Inflammatory Activity
Per Naturex/Givaudan TurmiPure Gold product specification
Moderate
Quercetin
Anti-Inflammatory Effects
500–1,000 mg/day; absorption enhanced significantly with vitamin C or bromelain; quer
Moderate
Taurine
Antioxidant and Anti-inflammatory Effects
500–3,000 mg/day; energy drinks typically contain 1,000 mg; athletic performance: 1–3
Moderate
Curcumin/Turmeric
Anti-Inflammatory Effects
RAW POWDER: 500-2000 mg/day = 60-100 mg curcumin. STANDARDIZED 95% curcuminoids: 400-
Moderate
Astaxanthin
Eye Health Benefits
4–12 mg/day from Haematococcus pluvialis extract; skin: 4–6 mg/day; exercise recovery
Moderate
MSM (Methylsulfonylmethane)
Osteoarthritis pain and function
Standard dose: 1.5-3 g/day, often split as 1 g twice daily. Joint applications: 3-6 g
Moderate
Neem (Azadirachta indica)
Plaque and Gingivitis Reduction (RCT-Confirmed)
PINGALI 2020 T2DM: 125/250/500 mg standardized neem BID = 250-1000 mg/day × 12 wk + m
Moderate
Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)
IBD cytokine modulation (Førland 2011)
ANDOSAN™ ORAL: 60 mL/day liquid extract × 7 weeks (multiple myeloma protocol). NSCLC
Moderate
Antrodia cinnamomea (Niu-Chang-Chih / Stout Camphor Fungus)
NASH 6-month RCT
NASH RCT: 3 capsules/day = 420 mg ACM × 6 months (n=28). SUBHEALTH ALT RCT: 250 mg AC
Moderate
AprèsFlex® / Aflapin® (Boswellia AKBA — Laila Nutraceuticals)
Osteoarthritis pain and function improvement
Standard dose: 100 mg twice daily (200 mg/day total) AprèsFlex®/Aflapin®. Onset of ef
Moderate
Aronia / Chokeberry (Aronia melanocarpa)
Possible Anti-Inflammatory Effects
STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day
Moderate
Bakuchi (Bakuchiol)
Antioxidant and anti-inflammatory mechanisms
TOPICAL: 0.5-1.0% bakuchiol cream 1-2×/day (Dhaliwal 2019: 0.5% × 12 wk = retinol-equ
Moderate
Benfotiamine
Diabetic peripheral neuropathy (mixed RCT results)
DIABETIC NEUROPATHY (BENDIP): 600 mg/day × 6 wk then 300 mg/day. BOND: 300 mg BID × 1
Moderate
Betalains (Beetroot Pigments)
Anti-inflammatory effects
BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI
Moderate
Bifidobacterium infantis 35624 (Align® / Bifantis® / Meta Align®)
Inflammatory cytokine modulation (gut-immune mechanism)
PIVOTAL: 100 million CFU/day (1×10⁸) — narrow window, both 1 million and 10 billion C
Moderate
Butcher's Broom (Ruscus aculeatus)
Symptomatic relief: heavy/tired legs, leg pain, tension
VANSCHEIDT 2002 PROTOCOL: 36-37.5 mg extract = 7-11 mg ruscogenins/day. ESCP guidelin
Moderate
Ellagic Acid
Metabolic syndrome — multiple markers improve together
METABOLIC SYNDROME (Hidalgo-Lozada 2022): 500 mg BID = 1000 mg/day pomegranate 90% EA
Moderate
Ferulic Acid
Reduced inflammatory markers
Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do
Moderate
GOPO® Rosehip (Hyben Vital — Rosa canina)
Hip and knee osteoarthritis pain relief
5 g/day rosehip powder (typically split as 2.5 g twice daily). Onset of pain relief:
Moderate
Jojoba Oil
Acne reduction (clay+jojoba mask, observational)
TOPICAL: 100% pure jojoba 1-2×/day, OR 5-10% in cosmetics. CLAY+JOJOBA MASK: 2-3×/wee
Moderate
Kutki (Picrorhiza kurroa)
Anti-inflammatory effects
TRADITIONAL AYURVEDIC: 250-500 mg dried rhizome 2-3×/day OR 1-3 g/day decoction. STAN
Moderate
Limonene (D-Limonene)
Anti-inflammatory effects (in elderly individuals)
GERD (Wilkins 2002 + Sun 2007): 1000 mg orally daily or QOD. CANCER PHASE I/II: 0.5-1
Moderate
Molecular Hydrogen (H2)
Anti-inflammatory effects (multiple conditions)
HRW: 1.5-7 ppm H2 in water, 0.5-2 L/day. LeBaron 2020 high-conc: ~7 ppm × 24 wk metab
Moderate
Mythocondro® (Non-Animal Chondroitin Sulfate — Gnosis by Lesaffre)
Knee OA improvement at 600 mg/day (pilot RCT)
PIVOTAL: 600 mg/day × 12 weeks (n=60 overweight knee OA). Notably lower than typical
Moderate
Phellinus linteus (Meshimakobu / Sanghuang)
Immune improvement RCT (, LDH cytotoxicity)
: PL mycelium extract 1,000 mg/day × 8 weeks (n=98, KCTC0399BP strain). IMMUNITY RCT:
Moderate
Phellodendron (Huang Bai)
Anti-inflammatory and antimicrobial effects (TCM traditional + mechanistic)
RELORA® (Phellodendron + Magnolia): 250 mg × 3/day = 750 mg/day. PHELLODENDRON ALONE
Moderate
Poria cocos / Wolfiporia cocos (Fu Ling / Hoelen / Tuckahoe)
Insomnia 21-adult polysomnography study (800 mg)
INSOMNIA: 800 mg ethanol extract nightly (21-adult polysomnography study). SLEEP COMB
Moderate
Protease (Proteolytic Enzymes)
Chronic inflammatory and circulatory conditions
Digestive: 30,000–60,000 HUT with meals; Systemic anti-inflammatory: Wobenzym® 3 tabl
Moderate
Punicalagins (Pomegranate Polyphenols)
Modest blood pressure reduction
POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED
Moderate
Resveratrol
Anti-inflammatory effects
150–500 mg/day trans-resveratrol; bioavailability enhanced with piperine or liposomal
Moderate
Rosehip (Rosa canina)
Reduced osteoarthritis pain (meta-analysis evidence)
STANDARD: 5 g/day rosehip powder (Hyben Vital® / LitoZin®) split 2-3 doses with meals
Moderate
Rosmarinic Acid
Anti-inflammatory effects via NF-κB inhibition
ALLERGIC RHINITIS: 50-200 mg/day Perilla × 21 d. AD COGNITION (Noguchi-Shinohara): 50
Moderate
Sesamin
Modest blood pressure reduction in hypertension (meta-analysis)
BP: 60 mg/day × 4 wk hypertensive. LIPID: 200-247 mg/day (Wu 2006: 50 g/d seed). 20-H
Moderate
Theracurmin® (Colloidal Nanoparticle Curcumin — Theravalues)
Osteoarthritis pain reduction
Theracurmin®: 30-180 mg/day (provides curcumin equivalent of much higher standard cur
Moderate
Yüth® (Spermidine)
Autophagy induction and cellular rejuvenation
1–10 mg/day spermidine (Yüth® formulation specifications); typical supplement use: 1.
Moderate
Bromelain
Anti-inflammatory and pain relief
200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d
Moderate
Cinnamon (Ceylon vs Cassia)
Anti-Inflammatory / Antioxidant
1-6 g/day cinnamon powder; 250-500 mg/day water-soluble extract (Cinnulin PF® standar
Moderate
Evening Primrose Oil (Oenothera biennis)
Eczema and atopic dermatitis improvement
3–6 g/day EPO (providing 240–480 mg GLA); eczema: 4–8 g/day; PMS: 3–4 g/day; diabetic
Moderate
Papain
Pharyngitis (sore throat) and oral inflammation
Digestive: 100,000–200,000 USP units per meal; Systemic anti-inflammatory: 200–400 mg
Moderate
Rutin
Anti-Inflammatory Effects
250-1,000 mg/day; often combined with vitamin C and other bioflavonoids
Moderate
Thyme (Thymus vulgaris)
Acute Bronchitis Cough Reduction (RCT-Confirmed)
BRONCHIPRET® THYME-IVY: 5.4 mL × 3/day × 11 d. BRONCHIPRET® TP: 1 tablet × 3/day × 11
Moderate
Xorialyc® (Olive Leaf Extract for Skin Inflammation)
Multiple Inflammatory Pathway Inhibition
300 mg/day (research-validated dose)
Moderate
Calanus® Oil (Arctic Zooplankton Omega-3 Wax Esters)
Cardiovascular and heart function improvement
2g/day Calanus® Oil capsules; clinical study: 2–4g/day; wax ester form may have diffe
Moderate
Glycyrrhizina (Licorice Flavonoids — BGG)
Anti-Inflammatory Skin Effects
Per BGG product specification
Limited
Guggul (Commiphora mukul)
Possible Anti-Inflammatory Activity
INDIAN RCTs: 50 mg guggulipid (~3.5 mg guggulsterones) BID × 12-24 wk. WESTERN: 1000-
Limited
Agmatine
Neuropathic Pain Reduction
PAIN TRIALS: 1.335-3.560 g/day. RCT: 2.670 g/day divided × 14 d. BODYBUILDING: 500 mg
Limited
Arnica (Arnica montana)
Post-surgical pain and swelling — formulation matters
TOPICAL (recommended): 20% tincture or 10-25% gel 2-4×/day. OTC: Arnicare®, Traumeel®
Limited
Auricularia auricula-judae (Wood Ear / Black Jelly Mushroom)
Anticoagulant polysaccharide antithrombin-mediated
EDIBLE WOOD EAR: dietary consumption common in Asian cuisine — supports general food-
Limited
Camu Camu
Anti-inflammatory effect
RCT: 70 mL 100% camu juice daily (~1050 mg vit C) × 7 d. POWDER SUPPLEMENTS: 100-500
Limited
Danshen (Salvia miltiorrhiza)
Cardiovascular use in TCM and Chinese hospital practice
ORAL ROOT: 9-15 g dried decoction OR 1-3 g powdered. STANDARDIZED: 500-1500 mg 2-3×/d
Limited
Faecalibacterium prausnitzii (Next-Generation Probiotic)
Anti-inflammatory effects in IBD
Clinical trial doses: typically 1-10 billion CFU/day in oxygen-protected formulations
Limited
Honokiol (Magnolia officinalis Bark)
Anti-inflammatory effects (preclinical)
Purified honokiol: 250 mg 1-2 times daily. Relora® (magnolia + phellodendron combinat
Limited
Japanese Knotweed (Polygonum cuspidatum)
Anti-inflammatory effects (small basketball player trial)
STANDARDIZED EXTRACTS (8% trans-resveratrol): 250-500 mg 1-2×/day → 20-40 mg resverat
Limited
Kaempferol
Anti-inflammatory Activity
NO STANDARDIZED CLINICAL DOSE. DIETARY: 5-10 mg/day Western, up to 50+ mg/day high-ve
Limited
Myricetin
Antioxidant and anti-inflammatory
DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1
Limited
Myrrh (Commiphora molmol)
Anti-inflammatory Activity (Mechanistic / Preclinical)
MIRAZID® antiparasitic: 600 mg (2 × 300 mg) daily empty stomach × 3-6 d. Soliman 2004
Limited
Oregano Oil (Origanum vulgare)
Enteric Parasite Activity (Limited Human Evidence)
FORCE 2000 ENTERIC PARASITES: 600 mg emulsified oregano oil daily × 6 wk. CONSUMER: 1
Limited
Pelargonidin
Anti-inflammatory effects (preclinical, strawberry RCTs)
DIETARY: ~30-50 mg glycosides per 150 g strawberries. STRAWBERRY RCTs: 250-500 g fres
Limited
Punarnava (Boerhavia diffusa)
Anti-inflammatory and antioxidant activities
TRADITIONAL: 1-3 g whole plant powder OR 250-500 mg standardized extract 2-3×/day. Pu
Limited
Pyritinol (Pyrithioxine / Encephabol)
Senile dementia cognitive support
Dementia (European Rx protocol): 200 mg hydrochloride three times daily (600 mg/day).
Limited
Sparassis crispa (Cauliflower Mushroom / Hanabiratake)
Highest β-glucan content (>40% dry weight)
β-GLUCAN content: >40% of dry weight (highest among medicinal mushrooms). MOUSE Sarco
Limited
Tributyrin (CoreBiome® Butyrate Prodrug)
Microbiome and inflammation effects (in vitro)
SHIME® IN VITRO: 300 mg cap + 450 mg softgel. FSU CrossOver: 300 mg/day × 4 wk (TERMI
Limited
Ursolic Acid
Anti-inflammatory and antioxidant effects (modest)
MUSCLE/STRENGTH: 400-450 mg/day divided (Bang 2014: 450 mg POSITIVE; Pereira 2020: 40
Limited
Wild Yam
Anti-inflammatory effects (mechanism-based)
TOPICAL CREAM: 2×/day × 3 mo. ORAL D. ALATA: 2 sachets/day = 12 mg phytosterol × 12 m
Limited
Wormwood (Artemisia absinthium)
Anti-Inflammatory and Antioxidant Effects
OMER 2007 Crohn's herbal blend: 3 × 500 mg/day × 10 wk. Krebs 2010: SedaCrohn® × 6 wk
Limited
Anatabine
General Anti-Inflammatory Activity
LAKHAN/KIRBY 2014 HASHIMOTO: 9-24 mg/day × 3 mo lozenges + vit A + D3. Former Anatabl
Limited
Burdock Root (Arctium lappa)
Knee Osteoarthritis Inflammation Reduction
MAGHSOUMI-NOROUZABAD 2016 OA: 3 cups burdock tea daily (each 2 g root in 150 mL boile
Limited
Luteolin
Neuroinflammation Reduction
100-300 mg/day general use; mast cell protocols often use luteolin 100-200 mg with qu
Limited
Serrapeptase (Serratiopeptidase)
Sinusitis and Upper Respiratory Inflammation
10-60 mg/day (typically 10-30 mg/day), standardized to 20,000-80,000 enzymatic units;
Limited
Cat's Claw (Uncaria tomentosa)
Anti-inflammatory and antioxidant activity
250–500 mg/day standardized POA extract; rheumatoid arthritis trials: 60 mg freeze-dr
Limited
Feverfew (Tanacetum parthenium)
Anti-inflammatory activity
50–300 mg/day dried leaf (standardized to ≥0.2% parthenolide); MIG-99: 6.25 mg three
Preliminary
Chrysin (5,7-Dihydroxyflavone)
Anti-inflammatory and antioxidant (mechanistic)
CRITICAL: poor oral bioavailability (<1%) — most marketed doses mechanistically irrel
Strong
5-Loxin® (Boswellia AKBA — PLT/OmniActive)
Knee osteoarthritis and joint comfort
100 to 250 mg once daily. Knee osteoarthritis trials used 100 mg/day and 250 mg/day o
Strong
AstaPure® (Natural Astaxanthin — Algatech)
Antioxidant and recovery support
4 to 12 mg per day, taken with a fat-containing meal for absorption.
Moderate
Almega®PL (Microalgae EPA Omega-3 — Qualitas)
Vegan EPA omega-3
A serving providing roughly 250 mg or more of EPA per day.
Moderate
Ayuflex® (Terminalia chebula Extract — Natreon)
Joint comfort and function
250 to 500 mg per day. The clinical trial used 250 mg twice daily.
Moderate
Brox-25® (Bromelain)
Inflammation and swelling
Commonly 200 to 500 mg (or defined enzyme-activity units) per day.
Moderate
CavaCurmin® (Curcumin Gamma-Cyclodextrin — Wacker)
Greatly improved absorption
About 500 mg of the complex per day; the bioavailability study compared standardized
Moderate
Curcumax® (Bioavailable Curcumin)
Mood support
Commonly 500 mg per day of the bioavailable formulation.
Moderate
Cureit® (Complete Natural Turmeric Matrix)
Muscle health in aging
Around 500 mg per day of the turmeric matrix.
Moderate
GliSODin® (Vegetal SOD with Gliadin — Isocell)
Antioxidant defense
Around 250 mg per day.
Moderate
NovaSOL® Curcumin (Liquid Micellar Curcumin — Aquanova)
Greatly enhanced absorption
Often a low dose of curcuminoids per day, since absorption is much higher than standa
Moderate
Oligopin® (French Maritime Pine Bark Extract — DRT)
Cardiometabolic support
Around 100 to 150 mg per day.
Moderate
Verilla® (Perilla Extract for Seasonal Allergy)
Seasonal allergy comfort
Around 50 to 200 mg of rosmarinic acid per day.
Limited
CuroWhite® (Hydrogenated Curcuminoids — Aurea)
Antioxidant and anti-inflammatory
Around 300 to 500 mg per day.
Limited
Oxxynea® (Fruit and Vegetable Polyphenols — Fytexia)
Antioxidant intake
A standardized daily polyphenol dose equivalent to several servings of produce.
Limited
Thymocid® (Black Cumin Seed Extract — Natural Remedies)
Anti-inflammatory support
A standardized daily dose providing a defined amount of thymoquinone.
Moderate
AKBAMax® / BosPure® (Boswellia serrata Standardized to AKBA — Arjuna)
Joint comfort
Around 100 to 250 mg per day of the standardized extract.
Strong
BioPure DHA® (Omega-3 DHA)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
Dry N-3® (Powdered Omega-3)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
DurOmega® (Stabilized Omega-3)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
EFADuo® (Omega-3 and Omega-6 Complex)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
Elantria® Algal DHA (Vegan Omega-3 DHA)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
EssentiOmega® (Omega-3 Concentrate)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Strong
V-Krill Omega® (Krill Omega-3)
Healthy triglycerides
Commonly 1 to 3 g of combined EPA and DHA per day.
Moderate
BioTurmin® (Bioavailable Turmeric)
Anti-inflammatory support
Commonly 500 to 1000 mg of curcuminoids per day.
Moderate
CurcuZen® (Curcumin Extract)
Anti-inflammatory support
Commonly 500 to 1000 mg of curcuminoids per day.
Limited
Curcumin C3 Reduct® (Tetrahydrocurcuminoids — Sabinsa)
Antioxidant defense
Commonly around 150 to 600 mg per day.
Moderate
GingerWarmer® (Ginger Extract)
Nausea relief
Commonly around 1 gram of ginger per day.
Moderate
Ginginoll® (Ginger Extract — Akay)
Nausea relief
Commonly around 1 gram of ginger per day.
Preliminary
NaturSYN® Defense (Anti-Inflammatory Botanical Blend)
Balanced inflammatory response
Per the product specification.
Moderate
AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)
Joint comfort
Around 100 to 250 mg of the standardized extract per day.
Limited
Attenutin® (Scutellaria and Acacia for Respiratory Health — Unigen)
Respiratory support
Per the product specification.