Home Ingredients OmniXan® (Zeaxanthin Standalone — OmniActive)
Eye HealthAntioxidant

OmniXan® (Zeaxanthin Standalone — OmniActive)

Capsicum annum
Evidence Level
Moderate
2 Clinical Trials
5 Documented Benefits
3/5 Evidence Score

OmniXan® is OmniActive's STANDALONE ZEAXANTHIN INGREDIENT — sourced from PAPRIKA (Capsicum annum), licensed from Kalsec. Distinguished from Lutemax 2020 by being zeaxanthin-only (without lutein) and from a different source (paprika vs marigold). Provides 3R,3'R zeaxanthin for applications wanting zeaxanthin alone or higher zeaxanthin ratios. Also available: OmniXan-RS (meso-zeaxanthin) which IS marigold-sourced. Used for: targeted zeaxanthin delivery, eye health, macular pigment building, blue light filtering.

Studied Dose 2-4 mg/day zeaxanthin (typical eye health dose)
Active Compound RR-zeaxanthin (3R,3'R) from paprika (Capsicum annum)

Benefits

Standalone Zeaxanthin from Paprika

OmniXan provides 3R,3'R zeaxanthin from PAPRIKA (Capsicum annum) — useful for formulators wanting zeaxanthin without lutein, or higher zeaxanthin ratios in custom formulations.

Supported by Trial 2, Trial 1

Macular Carotenoid

Zeaxanthin is one of three macular carotenoids (alongside lutein and meso-zeaxanthin); deposits in central macula (fovea) where lutein is more peripheral; important for central vision.

Supported by Trial 2

Blue Light Filtering

Zeaxanthin absorbs short-wavelength blue light (400-500 nm) protecting retinal photoreceptors from photo-oxidative damage.

Supported by Trial 2

Singlet Oxygen Quenching

Among the most potent natural quenchers of singlet oxygen and lipid radicals — relevant to retinal antioxidant defense.

Paprika-Source Distinction

Paprika source provides 3R,3'R zeaxanthin (the dietary form). Note: meso-zeaxanthin (3R,3'S) is sourced from marigold via OmniActive's separate OmniXan-RS product line.

Supported by Trial 2

Mechanism of action

1

Macular Pigment Deposition

Dietary 3R,3'R zeaxanthin deposits in central macular pigment, particularly the fovea — central vision area.

2

Blue Light Absorption

Zeaxanthin's molecular structure absorbs blue light (400-500 nm), reducing oxidative damage to photoreceptors.

3

Antioxidant Activity

Quenches singlet oxygen and lipid radicals; recycled by other antioxidants for sustained activity.

4

Source Distinction

OmniXan paprika-sourced 3R,3'R zeaxanthin is bioequivalent to dietary zeaxanthin from green leafy vegetables and corn; structurally identical.

Clinical trials

1
OmniXan Safety Evaluation — Mehta 2014
PubMed

Subchronic toxicity and mutagenicity safety evaluation of OmniXan™ paprika-derived RR-zeaxanthin (65%).

Rat models (acute, subchronic toxicity, mutagenicity).

Oral LD50 >2000 mg/kg/day; no adverse effects in subchronic studies; no mutagenic activity. Established safety profile for human supplementation. CRITICAL CAVEAT: this is a safety/toxicology study, not a clinical efficacy trial.

2
Zeaxanthin for Macular Pigment and AMD — Generic Evidence
PubMed

Multiple zeaxanthin trials including AREDS2 component evidence.

Adults including AMD-risk populations.

Established macular pigment building and visual function support. CRITICAL CAVEAT: most evidence from generic zeaxanthin or zeaxanthin+lutein combinations, not OmniXan-specific. Specific OmniXan clinical efficacy trials limited.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress (rare).
Yellow-orange tint to skin at very high doses (carotenodermia, harmless).
Allergic reactions to marigold rare.

Important Drug interactions

Generally minimal drug interactions.
Bile acid sequestrants — may modestly reduce carotenoid absorption.
Pregnancy — generally considered safe at moderate doses.
Lactation — generally safe.
Children — appropriate at proportional doses.

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Frequently asked questions about OmniXan® (Zeaxanthin Standalone — OmniActive)

What is OmniXan® (Zeaxanthin Standalone — OmniActive)?

OmniXan® is OmniActive's STANDALONE ZEAXANTHIN INGREDIENT — sourced from PAPRIKA (Capsicum annum), licensed from Kalsec.

What does OmniXan® (Zeaxanthin Standalone — OmniActive) do?

Dietary 3R,3'R zeaxanthin deposits in central macular pigment, particularly the fovea — central vision area. In clinical research, OmniXan® (Zeaxanthin Standalone — OmniActive) has been studied for standalone zeaxanthin from paprika, macular carotenoid, blue light filtering.

Who should take OmniXan® (Zeaxanthin Standalone — OmniActive)?

OmniXan® (Zeaxanthin Standalone — OmniActive) may be most relevant for people interested in eye health, antioxidant. It has been clinically studied for standalone zeaxanthin from paprika, macular carotenoid, blue light filtering. As with any supplement, consult your healthcare provider before starting, especially if you have medical conditions or take prescription medications.

How long does OmniXan® (Zeaxanthin Standalone — OmniActive) take to work?

Most clinical trial effects appear over weeks of consistent use; individual response varies. Acute or same-day effects (where applicable) typically appear within hours, but most cumulative benefits — particularly those affecting biomarkers, mood, sleep quality, or chronic symptoms — require 4-12 weeks of regular use to fully assess. If you don't notice benefit after 12 weeks at the appropriate dose, it may not be your responder.

When is the best time to take OmniXan® (Zeaxanthin Standalone — OmniActive)?

OmniXan® (Zeaxanthin Standalone — OmniActive) can typically be taken with breakfast or dinner — taking with food reduces GI sensitivity for most supplements. Specific timing matters less than daily consistency for cumulative effects. Always check product labeling and follow personalized guidance from your healthcare provider.

Is OmniXan® (Zeaxanthin Standalone — OmniActive) worth taking?

OmniXan® (Zeaxanthin Standalone — OmniActive) has moderate clinical evidence (Evidence Level 3/5 on NutraSmarts) — meaningful trial support exists, though results are less consistent than top-tier ingredients. Whether it's worth taking depends on your specific goals, what you've already tried, your budget, and your overall supplement strategy. The honest framing: no supplement is essential for most people, and lifestyle factors (sleep, exercise, diet, stress management) typically produce larger effects than any single supplement. OmniXan® (Zeaxanthin Standalone — OmniActive) is most worth trying if its evidence-supported uses align with your specific goals.

What is the recommended dosage of OmniXan® (Zeaxanthin Standalone — OmniActive)?

The clinically studied dose for OmniXan® (Zeaxanthin Standalone — OmniActive) is 2-4 mg/day zeaxanthin (typical eye health dose). Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is OmniXan® (Zeaxanthin Standalone — OmniActive) used for?

OmniXan® (Zeaxanthin Standalone — OmniActive) is studied for standalone zeaxanthin from paprika, macular carotenoid, blue light filtering. OmniXan provides 3R,3'R zeaxanthin from PAPRIKA (Capsicum annum) — useful for formulators wanting zeaxanthin without lutein, or higher zeaxanthin ratios in custom formulations.