Home Ingredients Pacran® (Whole Cranberry Powder — Naturex)
Kidney/Urinary TractWomen's Health

Pacran® (Whole Cranberry Powder — Naturex)

Vaccinium macrocarpon
Evidence Level
Strong
2 Clinical Trials
5 Documented Benefits
4/5 Evidence Score

Pacran® is a WHOLE CRANBERRY POWDER (Vaccinium macrocarpon) developed by Naturex (now Givaudan) — distinguished by use of WHOLE CRANBERRY (not just PAC extract) for comprehensive cranberry phytochemistry. Multiple RCTs for urinary tract health. Used for: urinary tract health, UTI prevention, women's urological health, frequent urination support.

Studied Dose 500 mg/day Pacran (research-validated dose)
Active Compound Whole cranberry phytochemistry — proanthocyanidins (PACs), organic acids, flavonoids

Benefits

UTI Prevention (Multiple RCTs)

Multiple Pacran RCTs demonstrate reduced UTI incidence in women with recurrent UTIs. 500 mg/day Pacran has clinical evidence for urinary tract health support.

Supported by Trial 1

A-Type Proanthocyanidins (PACs)

Cranberry's unique A-type PACs prevent E. coli adhesion to bladder wall — primary UTI prevention mechanism. Whole cranberry provides PAC plus additional cranberry compounds.

Supported by Trial 1, Trial 2

Frequent Urination Support in Women

Recent Pacran research established benefits for alleviating frequent urination in women.

Supported by Trial 2

Whole Cranberry Distinction

Pacran uses whole cranberry providing comprehensive phytochemistry — A-type PACs PLUS organic acids, flavonoids, anthocyanins.

Supported by Trial 1, Trial 2

Convenient Daily Dosing

500 mg single-capsule daily dose convenient for consistent urinary health support.

Mechanism of action

1

A-Type PAC Anti-Adhesion

Cranberry's unique A-TYPE PACs (most berries have B-type) prevent type-1 fimbriated E. coli adhesion to bladder uroepithelium. Without adhesion, bacteria cannot establish infection.

2

Bacterial Adhesion vs Antimicrobial

Cranberry doesn't kill bacteria — prevents adhesion. Mechanism distinct from antibiotics. Supports bacteria flushing via urination.

3

Whole Cranberry Phytochemistry

Beyond PACs: organic acids may modify urine pH; flavonoids provide antioxidant; comprehensive cranberry profile.

Clinical trials

1
Pacran for UTI Prevention — Multiple RCTs
PubMed

Multiple Pacran 500 mg/day RCTs in women with recurrent UTIs.

Women with recurrent UTIs.

Reduced UTI incidence vs placebo across studies.

2
Pacran for Frequent Urination in Women
PubMed

Recent clinical study of Pacran for alleviating frequent urination in women.

Women with frequent urination.

Improvements in frequency markers; established additional women's urological applications.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress.
Allergic reactions rare.
Pink/red urine possible (anthocyanin excretion).
Theoretical kidney stone risk in those prone to oxalate stones (cranberry has oxalates).

Important Drug interactions

WARFARIN — historical concern about cranberry-warfarin interaction; recent evidence suggests interaction is less significant than thought but consult.
Pregnancy — generally considered safe at supplemental doses.
Lactation — generally safe.
Kidney stone history — oxalate considerations.
Aspirin — cranberry contains salicylates; theoretical cumulative effects at high doses.

More Kidney/Urinary Tract Ingredients

Kidney/Urinary Tract
Exocyan™ (Cranberry Extract for UTI)
Exocyan™ is a STANDARDIZED CRANBERRY EXTRACT (Vaccinium macrocarpon) developed by Nexira (…
Kidney/Urinary Tract
Flowens™ (Cranberry for Men's & Women's Urological Health — Givaudan)
Flowens™ is a 100% NATURAL CRANBERRY ingredient from Givaudan — distinguished as the ONLY…
Kidney/Urinary Tract
MannoHealth™ (D-Mannose — Bioenergy Life Science)
MannoHealth™ is a HIGH-PURITY D-MANNOSE ingredient from Bioenergy Life Science (BLS) — dis…
Women's Health
Lactobacillus crispatus CTV-05 (LACTIN-V™)
A vaginal Live Biotherapeutic Product (LBP) commercialized by Osel Inc as Lactin-V™. Cohen…

Frequently asked questions about Pacran® (Whole Cranberry Powder — Naturex)

What is the recommended dosage of Pacran® (Whole Cranberry Powder — Naturex)?

The clinically studied dose for Pacran® (Whole Cranberry Powder — Naturex) is 500 mg/day Pacran (research-validated dose). Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Pacran® (Whole Cranberry Powder — Naturex) used for?

Pacran® (Whole Cranberry Powder — Naturex) is studied for uti prevention (multiple rcts), a-type proanthocyanidins (pacs), frequent urination support in women. Multiple Pacran RCTs demonstrate reduced UTI incidence in women with recurrent UTIs. 500 mg/day Pacran has clinical evidence for urinary tract health support.

Are there side effects from taking Pacran® (Whole Cranberry Powder — Naturex)?

Reported potential side effects may include: Generally well-tolerated. Mild GI distress. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Does Pacran® (Whole Cranberry Powder — Naturex) interact with medications?

Known drug interactions may include: WARFARIN — historical concern about cranberry-warfarin interaction; recent evidence suggests interaction is less significant than thought but consult. Pregnancy — generally considered safe at supplemental doses. Consult a pharmacist or healthcare provider if you take prescription medications.

Is Pacran® (Whole Cranberry Powder — Naturex) good for kidney/urinary tract?

Yes, Pacran® (Whole Cranberry Powder — Naturex) is researched for Kidney/Urinary Tract support. Multiple Pacran RCTs demonstrate reduced UTI incidence in women with recurrent UTIs. 500 mg/day Pacran has clinical evidence for urinary tract health support.