Home Ingredients VinCare® (Whole Grape Extract — Ethical Naturals)
CardiovascularAntioxidant

VinCare® (Whole Grape Extract — Ethical Naturals)

Vitis vinifera
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

VinCare® is a patented whole grape (Vitis vinifera) extract from Ethical Naturals, standardized to about 80% polyphenols including proanthocyanidins. A North American clinical study reported support for healthy cholesterol ratios and antioxidant activity, reflecting the cardiovascular value of grape polyphenols.

Studied Dose About 350 mg per day.
Active Compound Whole grape extract standardized to about 80% polyphenols (60 to 70% proanthocyanidins).

Benefits

Cholesterol and cardiovascular support

In a published clinical study, whole grape extract supported healthy cholesterol ratios (HDL to LDL) and cardiovascular markers.

Supported by Trial 1

Antioxidant defense

Grape polyphenols are potent antioxidants that protect LDL cholesterol and cells from oxidative damage.

Supported by Trial 1

Blood-vessel support

Grape proanthocyanidins support healthy blood-vessel function and circulation.

Supported by Trial 1

Mechanism of action

1

LDL protection

Grape polyphenols embed with LDL particles and shield their fats from oxidation, a key step in keeping arteries healthy.

2

Free-radical scavenging

The proanthocyanidins and other grape polyphenols neutralize free radicals and support the body's antioxidant defenses.

Clinical trials

1
Grape Extract and LDL Oxidation — Trial
PubMed

Trial of a standardized grape extract on LDL cholesterol's susceptibility to oxidation. (Vigna et al. 2003, Metabolism)

Adults.

The standardized grape extract reduced LDL cholesterol's susceptibility to oxidation; VinCare is a whole grape extract.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED.
Mild digestive upset or headache is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anticoagulants — grape polyphenols may have a mild additive effect; monitor.
Blood pressure medication — possible mild additive effect; monitor.
Tell your doctor before surgery.

Featured in these supplement guides

High Cholesterol→

More Cardiovascular Ingredients

Cardiovascular
Niacin
Niacin, or vitamin B3, is a vital nutrient that supports energy production by serving as a…
Cardiovascular
Omega-3 Fatty Acids
Omega-3 fatty acids, primarily eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), an…
Cardiovascular
Potassium
Potassium is the most abundant intracellular cation in the human body and an essential min…
Cardiovascular
Pycnogenol® (French Maritime Pine Bark)
Pycnogenol® (Horphag Research) is a standardized extract from the bark of French maritime…

Frequently asked questions about VinCare® (Whole Grape Extract — Ethical Naturals)

What is VinCare® (Whole Grape Extract — Ethical Naturals)?

VinCare® is a patented whole grape (Vitis vinifera) extract from Ethical Naturals, standardized to about 80% polyphenols including proanthocyanidins. A North American clinical study reported support for healthy cholesterol ratios and antioxidant activity, reflecting the cardiovascular value of grape polyphenols.

What is the recommended dosage of VinCare® (Whole Grape Extract — Ethical Naturals)?

The clinically studied dose for VinCare® (Whole Grape Extract — Ethical Naturals) is About 350 mg per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is VinCare® (Whole Grape Extract — Ethical Naturals) used for?

VinCare® (Whole Grape Extract — Ethical Naturals) is studied for cholesterol and cardiovascular support, antioxidant defense, blood-vessel support. In a published clinical study, whole grape extract supported healthy cholesterol ratios (HDL to LDL) and cardiovascular markers.

Are there side effects from taking VinCare® (Whole Grape Extract — Ethical Naturals)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED. Mild digestive upset or headache is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is VinCare® (Whole Grape Extract — Ethical Naturals) safe to take?

Whether VinCare® (Whole Grape Extract — Ethical Naturals) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED. It may also interact with certain medications. VinCare® (Whole Grape Extract — Ethical Naturals) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Vigna GB, Costantini F, Aldini G, et al. Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers. Metabolism. 2003;52(10):1250-7..PubMedUsed to support: Trial supporting grape extract protecting LDL cholesterol from oxidation (VinCare is a whole grape extract).