Top 5 — Ranked by Evidence
Very Strong
Caffeine
Enhances Alertness and Focus
100–400 mg/day; performance: 3–6 mg/kg body weight 60 minutes pre-exercise; upper safe
Strong
Nicotinamide Riboside
Documented blood NAD+ elevation
Standard dose: 250-1,000 mg/day NR. Most clinical trials use 300-600 mg/day. Take with
Very Strong
Glucose / Dextrose
Endurance exercise performance and glycogen sparing
WHO ORS: 13.5 g glucose/L (75 mmol/L) + 75 mmol/L Na. SPORTS: 4-8% solution (40-80
Very Strong
Iron
Energy metabolism
18 mg/day (women RDA); 27 mg/day (pregnant); 8 mg/day (men); therapeutic: 150–200 mg
Strong
CoEnzyme Q10
Mitochondrial myopathies
Heart failure (Q-SYMBIO): 100 mg 3×/day. Migraine: 100-300 mg/day. Statin myopathy:
📈 Fastest Growing Energy Ingredients
Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.
Trending
Strong
CoEnzyme Q10
Mitochondrial myopathies
Heart failure (Q-SYMBIO): 100 mg 3×/day. Migraine: 100-300 mg/day. Statin myopathy: 100-200…
Trending
Strong
Nicotinamide Riboside
Documented blood NAD+ elevation
Standard dose: 250-1,000 mg/day NR. Most clinical trials use 300-600 mg/day. Take with or…
Trending
Very Strong
Vitamin B12
Energy Metabolism
2.4 mcg/day (RDA); deficiency treatment: 1,000–2,000 mcg/day oral (sublingual preferred);…
🔬 Future Energy Ingredients to Watch
Lower current evidence but active research underway — these may become top picks within 2–3 years.
Watch
Moderate
TeaCrine® (Theacrine)
Sustained energy without tolerance
STANDARD: 100-300 mg/day (safety to 300 mg × 8 wk continuous). STACK: 125-150 mg TeaCrine® +…
Watch
Moderate
Ergothioneine (ErgoActive®)
Mitochondrial protection and bioenergetics
5–30 mg/day; most human studies use 5–20 mg/day; dietary intake from mushrooms typically 1–5…
Watch
Moderate
PrimaVie® (Shilajit Extract — Natreon)
Mitochondrial energy and CoQ10 potentiation
Clinical trial dose: 250 mg twice daily (500 mg/day total) for 90 days. CoQ10 potentiation…
Recommended Energy Products
Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.
Real products featuring the best-evidenced energy ingredients ranked above - chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.
Best for daily B-vitamin energy support
Amazon →
Thorne B-Complex #12
Active B vitamins with methyl-B12 + folate, 60 ct
Uses active methylated B12 and folate; third-party certified and well absorbed for daily energy metabolism.
Best for cellular energy production
Amazon →
Doctor's Best High Absorption CoQ10 with BioPerine
100 mg softgels, 120 ct
Naturally fermented CoQ10 with BioPerine to aid absorption at a reasonable per-serving cost; non-GMO, gluten-free.
Best for gentle iron replenishment
Amazon →
Thorne Iron Bisglycinate
25 mg elemental iron capsules, 60 ct
Ferrous bisglycinate is a well-absorbed, gentler chelated form many tolerate without the constipation of standard iron salts.
Best for stress-related fatigue
Amazon →
NOW Supplements Rhodiola 500 mg
500 mg (3% rosavins) veg capsules, 60 ct
Standardized adaptogen extract from a budget-friendly, widely stocked brand; vegetarian capsules.
All Energy Ingredients (137)
Very Strong
Caffeine
Enhances Alertness and Focus
100–400 mg/day; performance: 3–6 mg/kg body weight 60 minutes pre-exercise; upper safe
Strong
Nicotinamide Riboside
Documented blood NAD+ elevation
Standard dose: 250-1,000 mg/day NR. Most clinical trials use 300-600 mg/day. Take with
Very Strong
Glucose / Dextrose
Endurance exercise performance and glycogen sparing
WHO ORS: 13.5 g glucose/L (75 mmol/L) + 75 mmol/L Na. SPORTS: 4-8% solution (40-80
Very Strong
Iron
Energy metabolism
18 mg/day (women RDA); 27 mg/day (pregnant); 8 mg/day (men); therapeutic: 150–200 mg
Strong
CoEnzyme Q10
Mitochondrial myopathies
Heart failure (Q-SYMBIO): 100 mg 3×/day. Migraine: 100-300 mg/day. Statin myopathy:
Strong
Rhodiola Rosea
Stress and fatigue reduction
200–600 mg/day standardized extract; taken before meals
Very Strong
Vitamin B12
Energy Metabolism
2.4 mcg/day (RDA); deficiency treatment: 1,000–2,000 mcg/day oral (sublingual
Strong
enXtra® (Standardized Alpinia galanga Extract — OmniActive)
Sustained 5-hour alertness
300 mg/day (single serving) is the standard dose used across all published trials. Can
Strong
Mitopure® (Urolithin A — Amazentis)
Foundational mitochondrial function trials
Standard clinical dose: 500-1,000 mg/day Mitopure®. Most clinical trials use 500-1,000
Strong
Niagen® (Nicotinamide Riboside — ChromaDex)
Foundational blood NAD+ elevation evidence
Clinical trial doses: 250-1,000 mg/day Niagen®. Most studies use 300-600 mg/day. Take
Strong
PEAK ATP® (Disodium Adenosine Triphosphate)
Fatigue resistance and endurance maintenance
400 mg/day PEAK ATP® (disodium ATP); acute: 400 mg taken 30–60 minutes pre-exercise;
Strong
TestFACTOR® (Testosterone + Sexual Wellness)
Reduced fatigue and improved energy
PERFORMANCE: 325 mg/day × 8 wk testosterone + sexual function. ULTRA-PERFORMANCE: 650
Strong
Urolithin A
Muscle strength and endurance preservation
Standard dose: 500-1,000 mg/day urolithin A direct supplementation. Most clinical
Strong
InnovaTea® (Natural Caffeine from Tea — NutriScience)
Energy and alertness
Commonly 100 to 200 mg of caffeine per serving.
Strong
Kaneka Ubiquinol™ (Reduced Coenzyme Q10)
Cellular energy
Typically 100 to 200 mg per day.
Strong
NewCaff™ (Microencapsulated Natural Caffeine)
Energy and alertness
Commonly 100 to 200 mg per serving; performance studies use about 3 to 6 mg per kg.
Strong
Palatinose™ (Isomaltulose)
Low-glycemic carbohydrate energy
25–75 g per dose in acute glycemic and exercise trials, typically replacing sucrose or
Strong
PeakO2® (Adaptogenic Mushroom Blend)
Time to exhaustion and endurance extension
1–4g/day for ongoing use; 4g/day for clinical performance benefits (21-day loading);
Strong
PurCaf® (Organic Caffeine from Green Coffee)
Energy and alertness
Commonly 100 to 200 mg per serving; performance studies use about 3 to 6 mg per kg.
Strong
Riboflavin
Energy Metabolism
1.1–1.3 mg/day (RDA); migraine prevention: 400 mg/day (clinical studies); metabolic
Strong
Zynamite® S (Non-Stim Mental Energy — Water Soluble)
Improved mood and reduced fatigue
100–150 mg Zynamite® S (single dose, acute cognitive benefits within 30 minutes); 150
Strong
Acetyl-L-Carnitine (ALCAR)
Energy metabolism and mitochondrial support
COGNITIVE/AGING: 1500-3000 mg/day divided. DIABETIC NEUROPATHY: 1000 mg × 3/day = 3000
Strong
Cereboost™ (American Ginseng for Cognition — Givaudan)
Mental Fatigue Reduction
200 mg/day Cereboost (research-validated)
Strong
Ferractiv® (Iron Amino Acid Chelate — Biotron)
Energy and reduced fatigue
Commonly providing the daily iron requirement (around 18 mg, or more if correcting a
Strong
Pantothenic Acid
Supports Energy Metabolism
AI (Adequate Intake): 5 mg/day adults (no RDA). PREGNANCY: 6 mg/day. LACTATION: 7
Strong
Ubiqsome® (Coenzyme Q10 Phytosome — Indena)
Mitochondrial Energy Production
100-300 mg/day Ubiqsome (CoQ10 equivalent)
Strong
Ubiquinol (Reduced CoQ10)
Mitochondrial Function
100-300 mg/day for general use; 200-400 mg/day for heart failure adjunct; 100-200
Moderate
Cluster Dextrin® (Highly Branched Cyclic Dextrin)
Sustained energy without insulin spikes
15–70 g pre- or intra-workout (typical: 30–50 g mixed in 500 mL fluid). Endurance
Moderate
HydroMax®
Endurance performance support
Pre-exercise glycerol hyperhydration: typically 1.0–1.5 g glycerol per kg body weight
Moderate
TeaCrine® (Theacrine)
Sustained energy without tolerance
STANDARD: 100-300 mg/day (safety to 300 mg × 8 wk continuous). STACK: 125-150 mg
Moderate
Capsinoids (Non-Pungent Capsaicin Analogs)
Increased energy expenditure and fat oxidation
WEIGHT MANAGEMENT (Snitker 2009 + Galgani 2010): 6 mg capsinoids daily × 4-12 wk.
Moderate
Ginseng
Energy and Fatigue Reduction
200–400 mg/day standardized extract (ginsenosides ≥4–7%); American ginseng: 100–200
Moderate
NMN (Nicotinamide Mononucleotide)
NAD+ restoration
250–500 mg/day (commonly studied); up to 1,200 mg/day in clinical trials
Moderate
RiaGev® (NR + D-Ribose NAD+ Complex)
Synergistic NAD+ elevation beyond NR alone
250–500 mg/day RiaGev®; formulated to optimize both NR and ribose at doses below their
Moderate
Robuvit® (French Oak Wood Extract)
Chronic fatigue reduction
300 mg/day Robuvit®; fatigue studies use 300 mg/day; athletic performance: 300 mg/day
Moderate
zümXR® (Targeted-Release Caffeine Technology — PLT Health)
Sustained energy without spike or crash
Caffeine doses typically 50-300 mg per serving (matching immediate-release caffeine
Limited
Guayusa (AMATEA® Organic Guayusa)
Clean energy and sustained focus
300–600 mg/day AMATEA® extract (providing 50–100 mg natural caffeine equivalent);
Moderate
Alpinia galanga (Greater Galangal)
Caffeine-free alertness and attention
300 mg/day standardized Alpinia galanga rhizome extract — the dose used in published
Moderate
B-Complex (Combined B Vitamins)
Energy Metabolism Support
1× RDA (basic) to 5-10× RDA (high-potency) of each B vitamin; varies by product
Moderate
BioPQQ® (Pyrroloquinoline Quinone — Mitsubishi)
Mitochondrial and energy support
About 20 mg per day.
Moderate
Black Ginger (Kaempferia parviflora / Krachaidum / Thai Ginseng)
Fat oxidation and energy metabolism
Standard dose: 100-180 mg/day standardized extract (typically 5-7% methoxyflavones).
Moderate
Cantaloupe Fruit Powder (SOD B Extramel®)
Promotes energy and reduced fatigue
10 mg/day SOD B Extramel® (≈140 IU SOD) once daily for 4–12 weeks; some studies have
Moderate
Cordyceps
Exercise performance and endurance
1,000–3,000 mg/day mycelium powder; 400–800 mg/day standardized extract
Moderate
D-Ribose (Bioenergy Ribose®)
ATP regeneration and cellular energy recovery
5–15 g/day in divided doses; athletic performance: 5 g pre/post exercise;
Moderate
Dynamine® (Methylliberine)
Fast-onset energy and focus
100–200 mg Dynamine® standalone; 100 mg Dynamine® + 100–200 mg caffeine (synergistic
Moderate
Eleuthero / Siberian Ginseng (Eleutherococcus senticosus)
Athletic Performance and Endurance
300-1,200 mg/day standardized extract; root powder 1-3 g/day
Moderate
EnduBerry™ Nu
Improved endurance running performance (branded crossover RCT)
Anthocyanin-rich serving before exercise
Moderate
Guarana (Paullinia cupana)
Stimulation / Energy / Alertness (Caffeine Mechanism)
75-200 mg guarana extract typical in supplements (provides ~30-100 mg caffeine); whole
Moderate
Oyster Extract
Supports Energy and Recovery
Typical supplemental doses 500-1500 mg oyster extract daily; clinical trials have used
Moderate
PurTea® (Organic Green Tea Caffeine — Applied Food Sciences)
Energy and alertness
Commonly 100 to 200 mg of caffeine per serving.
Moderate
Rhodiolife®
Stress-related fatigue reduction
200–400 mg/day of standardized Rhodiola rosea extract in stress, anxiety, and fatigue
Moderate
SalidroPure™ (Pure Salidroside)
Anti-fatigue and endurance
3–5 mg/day pure salidroside (equivalent to ~500 mg 1% standardized Rhodiola extract)
Moderate
Theobromine
Long-Lasting Mild Energy
Controlled trials have used 250-1000 mg pure theobromine acutely and 700-979 mg/day
Moderate
All-Q® (Bioavailable Coenzyme Q10)
Cellular energy
Typically 100 to 200 mg per day.
Moderate
Carb10® (Pea Starch Carbohydrate)
Sustained workout energy without GI distress
15–25g per serving for workout fueling; can be used pre, intra, or post-workout;
Moderate
CarnoLife® (L-Carnitine L-Tartrate)
Energy metabolism
Commonly 1 to 2 grams of L-carnitine L-tartrate per day.
Moderate
Chocamine® (Cocoa Extract — RFI)
Smooth energy and focus
Commonly around 500 mg to 1.5 g of cocoa extract per day.
Moderate
Coffee Fruit Extract (CoffeeFruit Pure™)
Energy without jitters
100–200 mg/day whole coffee fruit concentrate; NeuroFactor™ clinical dose: 100 mg/day
Moderate
ElevATP®
Supports Endogenous ATP Production
150 mg/day in branded human studies, taken with or without other workout ingredients.
Moderate
Ergothioneine (ErgoActive®)
Mitochondrial protection and bioenergetics
5–30 mg/day; most human studies use 5–20 mg/day; dietary intake from mushrooms
Moderate
FastBliss® (Paraxanthine)
Energy and alertness without the crash
50–200 mg/day paraxanthine; cognitive benefits at doses as low as 50 mg; full effect
Moderate
goBHB® (Beta-Hydroxybutyrate Ketone Salts)
Physical performance and endurance support
6–12g BHB salts to achieve meaningful blood ketone elevation (0.5–1.0 mmol/L);
Moderate
MCT Oil (Medium-Chain Triglycerides)
Rapid energy production and ketone generation
15–30 mL/day (1–2 tablespoons); start with 5–10 mL and increase gradually to avoid GI
Moderate
NEOBEE® (Medium-Chain Triglycerides — Stepan)
Fast energy
Commonly 10 to 20 grams per day with meals.
Moderate
PQQ (Pyrroloquinoline Quinone)
Mitochondrial biogenesis stimulation
10–20 mg/day; 20 mg most studied for cognitive effects; often combined with 200–300 mg
Moderate
SaraPEPP™ Nu
Caffeine-free cognitive/energy support
Daily with MCT carrier
Moderate
Sucrosomial Magnesium
Energy and fatigue
Bioavailability research administered around 350 mg elemental magnesium; products
Moderate
Yerba Mate (Ilex paraguariensis)
Energy and Mental Alertness
1-3 g dried leaves per day (typical traditional consumption); 500-2,000 mg/day
Limited
Potassium Aspartate
Cellular Energy Support Claim
Combination trials used roughly 12 mmol potassium with 6 mmol magnesium (as
Limited
MitoGreens® (Ergothioneine-Amplified Superfood Greens — NNB Nutrition)
Quercetin inflammation + mitochondria support
100 mg/day MitoGreens — concentrated dose enabling broad formulation. Actual MitoPrime
Limited
Oxaloacetate (Anhydrous Enol)
Cellular energy metabolism support
Standard dose: 100-300 mg/day anhydrous enol oxaloacetate (benaGene™). Cognitive
Limited
Sabrolithin® A&B (Urolithin A + Urolithin B)
Mitochondrial Health Support (via Urolithin A)
Urolithin A trials commonly used 500–1,000 mg/day; no well-established human clinical
Limited
AfperFIT™
Increased energy expenditure / thermogenesis
500 mg/day, 6-paradol
Limited
Bromantane (Ladasten)
Asthenic disorders / neurasthenia (pivotal 728-patient multicenter trial)
RUSSIAN APPROVED (asthenia): 50-100 mg/day morning × 28 days. NOOTROPIC: 25-50 mg/day.
Limited
GlycerPump™
Endurance performance (glycerol class)
No branded GlycerPump™ RCTs. Glycerol-class hyperhydration protocols typically use
Limited
GlycerSize™
Endurance performance (glycerol class)
No branded GlycerSize™ RCTs. Glycerol-class hyperhydration protocols typically use
Limited
PANMOL® NADH Micro
Cellular Energy Support
5-10 mg/day taken sublingually or on an empty stomach in morning; CFS trial used 10
Limited
PureATP (Pure Adenosine 5'-Triphosphate Disodium)
Energy Support
400 mg/day disodium ATP (extrapolated from PEAK ATP research; PureATP-specific studies
Limited
Sulbutiamine (Arcalion)
Asthenia and chronic fatigue improvement
ASTHENIA (Arcalion approved): 200-600 mg/day divided. Shipelowitz 1984 best at 600 mg.
Limited
Axivite® (Energy and Cognitive Performance Ingredient)
Sustained energy and mental alertness
Per Axivite® product specifications; clinical dosing per SEE Nutrition product
Limited
Bemethyl (Bemitil / Metaprot)
Asthenic disorders (1988 RCT vs piracetam/pyriditol)
RUSSIAN/CIS APPROVED: 250-500 mg 1-2×/day for asthenia; courses 3-5 days with 2-3 day
Limited
CordycepsPrime™ (Branded Cordyceps Extract)
Exercise tolerance and aerobic capacity support
CordycepsPrime™ label dose per manufacturer; broader cordyceps literature has used 1–4
Limited
Magnesium Aspartate
Energy metabolism
Repletion typically targets 200-400 mg elemental magnesium daily; older fatigue
Limited
Metabolyte® (BHB Energy + B-Vitamins)
Dual-pathway cellular energy support
Per Compound Solutions product specifications; typical BHB component 3–6g; combined
Limited
p-Synephrine (Bitter Orange)
Pre-Activity Energy
Most human studies used p-synephrine 25-50 mg per day, alone or combined with caffeine
Limited
Pyruvate (Calcium Pyruvate / Sodium Pyruvate)
Improvements in mood and perceived energy
MODERN: 5-10 g/day Ca/Na pyruvate (Kalman 1999: 6 g/day × 6 wk). STANKO 1990s: 22-53
Limited
SantEnergy™ Nu
Caffeine-free energy support
400 mg twice daily
Limited
Sodium Phosphate
Phosphate As An Energy Substrate
Loading protocols typically use about 1 g of sodium phosphate four times daily
Limited
Coconut Oil
Energy Boost
15–30 mL/day (1–2 tablespoons); MCT oil fractionated from coconut: 15–30 mL/day;
Limited
CordyFuel™ (Branded Cordyceps Extract)
Supports exercise endurance and oxygen utilization
Branded-specific dosing is not well defined in indexed trials. Class-level cordyceps
Limited
EnergySMART® (Low-Glycemic Carbohydrate Complex — Anderson)
Sustained energy
Per the product or recipe.
Limited
Finomate® (Green Mate Extract — Frutarom)
Appetite and energy
Per the product specification.
Limited
FitNox® (Plant Nitric Oxide Complex)
Energy and stamina
Around 250 mg per day.
Limited
GeeQTen® (Coenzyme Q10)
Cellular energy
Commonly 100 to 200 mg per day.
Limited
goFAT® (Structured Lipid Blend)
Rapid ketogenic fuel and energy
Per product label; typical fat blend 5–15g/day; MCT component provides rapid ketone
Limited
Kinetiq® (Bitter Orange Extract — Novel Ingredients)
Energy and alertness
Commonly providing around 50 mg of p-synephrine per day.
Limited
Lipofer® (Microencapsulated Iron — Lubrizol)
Energy and oxygen transport
Providing a typical supplemental iron dose, often around 14 to 18 mg per day.
Limited
Magnesium Gluconate
Energy metabolism
Repletion targets roughly 200-400 mg elemental magnesium daily, which requires
Limited
Magnesium Lactate
Energy metabolism
Repletion typically targets 200-400 mg elemental magnesium daily; sustained-release
Limited
Magnesium Malate
Energy and Fatigue Support
200–600 mg elemental magnesium/day; fibromyalgia trials used 1,200–2,400 mg magnesium
Limited
Magnesium Orotate
Energy metabolism
Cardiac research used grams of the salt daily (e.g., 6,000 mg tapering to 3,000 mg),
Limited
Phenylpiracetam (Phenotropil / Carphedon)
Asthenia and chronic fatigue syndrome
RUSSIAN: 100-200 mg/day divided morning + early afternoon. STROKE/TBI: 200-400 mg/day.
Limited
Testncrease® (Testosterone Support Blend)
Energy, mood, and vitality
Per Testncrease® product specifications; typically 2 capsules/day with meals; clinical
Limited
TruFulvic® (Fulvic Acid from Shilajit — Natreon)
Cellular energy
Commonly around 250 to 500 mg per day.
Limited
α-Lacys Reset® (Alpha-Lipoic Acid and Cysteine Complex — Nutraceutics)
Energy and recovery
Used at a low daily dose within finished formulas (for example, about 25 mg).
Moderate
Adenosine 5'-Triphosphate (ATP)
Energy Currency Support
400 mg/day disodium ATP (research-validated dose, primarily based on PEAK ATP studies)
Preliminary
Glucuronolactone (D-Glucurono-γ-Lactone)
Component of energy drink combinations
RED BULL: 600 mg per 250 mL serving. EU SCF safe up to 250 mg/kg/day (2003). ISOLATED
Moderate
Codonopsis pilosula (Dang Shen / Poor Man's Ginseng)
Chronic fatigue 8-week pilot RCT (Frontiers in Pharmacology 2021)
TCM TYPICAL: 9-15 g/day root decoction. oncology adjunct: oral liquid (approved
Moderate
PrimaVie® (Shilajit Extract — Natreon)
Mitochondrial energy and CoQ10 potentiation
Clinical trial dose: 250 mg twice daily (500 mg/day total) for 90 days. CoQ10
Moderate
Shilajit
Mitochondrial energy and CoQ10 potentiation
Standard clinical dose: 250 mg twice daily (500 mg/day total) of purified shilajit
Limited
ALIVEL® (Tongkat Ali — Eurycoma longifolia)
Energy and vitality
Commonly around 100 to 200 mg per day.
Limited
Bee Pollen
Supports energy and stamina
Traditional intake ranges from 1 teaspoon (about 5 g) to 1 tablespoon (15 g) daily;
Limited
GS15-4® (Enzyme-Fermented Ginseng — Ilhwa)
Energy and vitality
Around 165 mg of fermented ginseng extract per day.
Preliminary
Actiful® (Orange and Pomegranate Complex — Solabia)
Energy and vitality
Around 600 to 700 mg per day.
Strong
Carnipure® (L-Carnitine — Lonza)
L-carnitine for energy metabolism
Same as generic L-carnitine: 1-3 g/day general supplementation. Specific applications:
Strong
FerroChel® (Ferrous Bisglycinate Chelate)
Iron for energy (deficiency-related)
Typical FerroChel® doses provide 14–28 mg elemental iron once daily for routine
Strong
LJ100® (Tongkat Ali — HP Ingredients)
Testosterone support trials
Standard formulation use: 100-300 mg LJ100® daily. Most clinical trials use 200
Strong
Methylcobalamin (Active B12)
B12 for energy metabolism
500-2,000 µg/day sublingual or oral for general supplementation; 1,000-2,500 µg/day
Strong
Tesnor® (Pomegranate + Cocoa Testosterone Support — Saanroo)
Testosterone increase in young men
400 mg/day Tesnor is the optimal clinical dose used across all three pivotal RCTs. 200
Moderate
AB-Fortis® (Microencapsulated Iron — Frutarom)
Iron for energy (deficiency-related)
Per AB-Fortis product specification (typical 8-18 mg elemental iron/day)
Moderate
Advantra Z® (Bitter Orange p-Synephrine — Nutratech)
Fat oxidation during exercise
Commonly 50 mg of p-synephrine per day, often taken before activity.
Moderate
CardaMind™ (Black Cardamom Cognitive Performance — Akay Bioactives)
Caffeine-free energy & focus
250 mg/day CardaMind (MA2-24) — the dose used in the pivotal clinical trial. Effects
Moderate
enfinity® Paraxanthine
Paraxanthine — clean energy
100-200 mg per serving; 50, 100, and 200 mg evaluated in published dose-response trials.
Moderate
Paraxanthine
Caffeine metabolite — clean energy
50-200 mg as a single acute dose; 100-200 mg is the most commonly studied range for
Moderate
Sodium Citrate
Extracellular Buffering Support
Ergogenic protocols use 0.3-0.5 g/kg body mass (about 0.5 g/kg most effective), taken
Limited
Beef Heart (Desiccated)
Richest natural food source of CoQ10
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef
Limited
Beef Liver (Desiccated)
Highest natural source of preformed vitamin A (retinol)
Typical supplementation: 3-6 g/day (4-8 capsules at 750 mg each) desiccated beef
Limited
Beef Spleen (Desiccated)
Highest natural source of heme iron
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef
Limited
Catuaba (Trichilia catigua)
Dopamine-mediated antidepressant-like mechanism
TRADITIONAL TINCTURE: 30-60 drops 2-3×/day. CAPSULE: 500-1,000 mg standardized bark
Limited
elemin® (Senonian Trace Minerals — VDF FutureCeuticals)
Trace-mineral support
Per the product specification.
Limited
Mildronate (Meldonium)
Energy & exercise capacity
RUSSIAN/LATVIAN APPROVED: 500-1,000 mg/day oral. POST-MI: 1,000 mg/day IV × 10-14
Limited
Pfaffia paniculata / Hebanthe eriantha (Brazilian Ginseng / Suma)
Adaptogen for energy (traditional)
Traditional: 500-1,500 mg root powder daily. Standardized extracts: dose varies by
Limited
Phenylethylamine (β-PEA)
Trace Amine Pathway Support
100-500 mg orally as a single acute dose; effects are very brief (<10 minutes) due to
Preliminary
ChloroBlast® (Alfalfa Chloroplast Concentrate — Ingredients by Nature)
Green-nutrient support
Per the product specification.
Preliminary
Hordenine
Stimulant energy (preliminary)
TYPICAL: 25-100 mg per serving in pre-workouts/fat burners. Often combined with
Preliminary
MineralLogic MLG-50®
Provides Plant-Source Trace Minerals
Manufacturer-recommended servings typically 100-300 mg daily; no validated clinical
Preliminary
Potassium Orotate
Provides Some Potassium
No established evidence-based dose exists for potassium orotate specifically; products