Home Ingredients CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)
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CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)

Evidence Level
Moderate
1 Clinical Trial
6 Documented Benefits
3/5 Evidence Score

CitrOlive® is a PATENTED MEDITERRANEAN INGREDIENT developed by Frutarom Health (now IFF) — combining olive (Olea europaea) and citrus extracts in synergistic formulation. Distinguished by Mediterranean diet-inspired positioning and clinical research at Murcia University (UCAM), Spain. Used for: cardiovascular health, arterial protection, antioxidant defense, anti-inflammatory support.

Studied Dose Per Frutarom CitrOlive product specification
Active Compound Olive polyphenols + citrus flavonoids (proprietary patented combination)

Benefits

Cardiovascular Health Support

CitrOlive's combined olive + citrus polyphenol approach supports overall cardiovascular health markers.

Supported by Trial 1

Arterial Hardening Protection

Frutarom positioning emphasizes protection against arterial hardening — atherosclerosis is underlying cause of most heart problems.

Mediterranean Diet Heritage

Concentrates Mediterranean diet phytonutrients — combining olive (foundational Med diet ingredient) with citrus.

Antioxidant + Anti-Inflammatory Synergy

Combined polyphenols provide synergistic antioxidant and anti-inflammatory activity.

Water-Soluble Versatility

Suitable for functional food and beverage applications, dietary supplements, nutrition bars.

UCAM Clinical Trial

Double-blind, placebo-controlled clinical trial at Murcia University (UCAM), Spain validates cardiovascular markers.

Supported by Trial 1

Mechanism of action

1

Olive Polyphenols

Olive provides hydroxytyrosol, oleuropein, and related polyphenols with documented cardiovascular and antioxidant effects.

2

Citrus Flavonoids

Citrus provides hesperidin, naringin, and related flavonoids with vascular and antioxidant activity.

3

Synergistic Combination

Frutarom's proprietary formulation creates synergy between olive and citrus polyphenol classes.

4

Endothelial Function Support

Both olive and citrus polyphenols support endothelial nitric oxide and vascular function.

Clinical trials

1
CitrOlive Cardiovascular Markers — Murcia University Trial

Double-blind placebo-controlled trial at Murcia University (UCAM), Spain.

Adults with cardiovascular concerns.

Cardiovascular health markers improvements; established CitrOlive cardiovascular evidence.

About this ingredient

About the active ingredient

CITROLIVE® is a PATENTED MEDITERRANEAN INGREDIENT developed by FRUTAROM HEALTH (now IFF) combining OLIVE (Olea europaea) and CITRUS extracts. POSITIONING: 'supports overall cardiovascular health and protects against the hardening of the arteries.' KEY DISTINCTIONS: (1) PATENTED proprietary olive + citrus combination; (2) MEDITERRANEAN DIET inspiration; (3) Clinical research at Murcia University (UCAM), Spain; (4) Water-soluble for versatile applications.

EVIDENCE-BASED USES: (1) Cardiovascular health; (2) Arterial protection; (3) Antioxidant + anti-inflammatory; (4) Mediterranean diet phytonutrient delivery.

CRITICAL CAUTIONS: (1) DOSE — per Frutarom specification; (2) ANTIHYPERTENSIVES — modest additive effects; (3) PREGNANCY — culinary olive/citrus safe; concentrated supplementation limited data; (4) MEDITERRANEAN DIET context — olive and citrus are foundational Med diet ingredients; CitrOlive concentrates these phytonutrients; (5) FOR COMPREHENSIVE CARDIOVASCULAR HEALTH — diet, exercise, weight management foundational; supplements adjunct; (6) BRAND VERIFICATION — CitrOlive® is Frutarom/IFF trademark.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress (rare).
Allergic reactions to olive or citrus rare.
Bitter taste possible at concentrated doses.

Important Drug interactions

ANTIHYPERTENSIVES — modest additive BP effects.
Anticoagulants — modest effects.
Statins — possible modest interactions.
CYP3A4 substrates — citrus component may affect; consult.
Pregnancy — culinary olive and citrus safe; concentrated supplementation limited specific data.
Lactation — generally safe.

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Frequently asked questions about CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)

What is the recommended dosage of CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)?

The clinically studied dose for CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) is Per Frutarom CitrOlive product specification. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) used for?

CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) is studied for cardiovascular health support, arterial hardening protection, mediterranean diet heritage. CitrOlive's combined olive + citrus polyphenol approach supports overall cardiovascular health markers.

Are there side effects from taking CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)?

Reported potential side effects may include: Generally well-tolerated. Mild GI distress (rare). Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Does CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) interact with medications?

Known drug interactions may include: ANTIHYPERTENSIVES — modest additive BP effects. Anticoagulants — modest effects. Consult a pharmacist or healthcare provider if you take prescription medications.

Is CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) good for cardiovascular?

Yes, CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom) is researched for Cardiovascular support. CitrOlive's combined olive + citrus polyphenol approach supports overall cardiovascular health markers.