Home Ingredients Cran-d'Or® (Cranberry Extract)
Kidney/Urinary TractWomen's HealthImmune Support

Cran-d'Or® (Cranberry Extract)

Vaccinium macrocarpon
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Cran-d'Or® is a cranberry (Vaccinium macrocarpon) extract standardized for proanthocyanidins (PACs). Cranberry is the classic natural option for urinary tract health, working largely by keeping bacteria from sticking to the bladder wall.

Studied Dose Commonly around 500 mg of cranberry concentrate per day.
Active Compound Cranberry (Vaccinium macrocarpon) concentrate providing proanthocyanidins (PACs).

Benefits

Urinary tract health

Cranberry is widely studied for supporting urinary tract health and reducing recurrent urinary tract infections, recognized among non-antibiotic options.

Supported by Trial 1

Anti-adhesion action

Cranberry proanthocyanidins help stop certain bacteria from sticking to the bladder wall, the leading proposed mechanism.

Supported by Trial 1

Antioxidant support

Cranberry polyphenols provide antioxidant support beyond the urinary tract.

Supported by Trial 1

Mechanism of action

1

Type-A proanthocyanidins

Cranberry's distinctive type-A PACs interfere with the fimbriae E. coli use to adhere to the urinary lining, helping bacteria be flushed out.

2

Polyphenol antioxidants

Cranberry's broad polyphenols add antioxidant activity supporting overall health.

Clinical trials

1
Cranberry and Urinary Tract Health — Review
PubMed

Review of non-antibiotic interventions, including cranberry, to prevent recurrent urinary tract infections. (Santer et al. 2026, British Journal of General Practice)

Adults prone to recurrent UTIs.

The review supports cranberry among non-antibiotic options for reducing recurrent urinary tract infections.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED.
Mild digestive upset at high doses.
Very high intake may raise kidney-stone risk in susceptible people.

Important Drug interactions

Warfarin — cranberry may interact; monitor INR if combined.
Not a substitute for antibiotics during an active infection.
Tell your doctor about a history of kidney stones.

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Frequently asked questions about Cran-d'Or® (Cranberry Extract)

What is Cran-d'Or® (Cranberry Extract)?

Cran-d'Or® is a cranberry (Vaccinium macrocarpon) extract standardized for proanthocyanidins (PACs). Cranberry is the classic natural option for urinary tract health, working largely by keeping bacteria from sticking to the bladder wall.

What is the recommended dosage of Cran-d'Or® (Cranberry Extract)?

The clinically studied dose for Cran-d'Or® (Cranberry Extract) is Commonly around 500 mg of cranberry concentrate per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Cran-d'Or® (Cranberry Extract) used for?

Cran-d'Or® (Cranberry Extract) is studied for urinary tract health, anti-adhesion action, antioxidant support. Cranberry is widely studied for supporting urinary tract health and reducing recurrent urinary tract infections, recognized among non-antibiotic options.

Are there side effects from taking Cran-d'Or® (Cranberry Extract)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED. Mild digestive upset at high doses. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Cran-d'Or® (Cranberry Extract) safe to take?

Whether Cran-d'Or® (Cranberry Extract) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED. It may also interact with certain medications. Cran-d'Or® (Cranberry Extract) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Santer M, Miller S, Fraser S, et al. Non-antibiotic interventions to prevent recurrent urinary tract infections. Br J Gen Pract. 2026;(advance)..PubMedUsed to support: Review supporting urinary-tract benefit of cranberry (the active in this branded cranberry).