Benefits
Vascular Health and Microcirculation
Mirtoselect anthocyanins improve microcirculation, capillary integrity, and venous function. Foundational application — basis for chronic venous insufficiency adjunct use and circulation support.
Retinal Health and Dry Eye
Improved oxygen and blood delivery to eye via microcirculation; supports retinal function in retinal challenges. Restores tear secretion functionality and supports dry eye discomfort.
Contrast Sensitivity in Retinal Health
Multiple trials show Mirtoselect improves contrast sensitivity — relevant to night vision, age-related visual decline, retinal stress.
Antioxidant Free-Radical Scavenging
Anthocyanins are potent antioxidants; counteract oxidative stress relevant to eye health, cardiovascular health, and aging.
Brain Health / Emotional Wellbeing (Recent)
Recent human study showed Mirtoselect benefits brain health with focus on emotional wellbeing. Emerging mood and cognitive applications via blood-brain barrier crossing anthocyanins.
Sustainable Wild-Harvest
Wild bilberries hand-picked in Northern/Eastern European forests by rural families and small suppliers; supports biodiversity and rural economy; zero-waste circular production.
Mechanism of action
Anthocyanin Capillary Integrity
Anthocyanins reduce capillary permeability and improve capillary integrity — foundation of venous insufficiency and microcirculation applications.
Retinal Microcirculation
Improves blood and oxygen delivery to retinal tissue — relevant to retinal challenges and eye health.
Antioxidant / Free Radical Scavenging
15 individual anthocyanin types provide comprehensive antioxidant activity at retinal, vascular, and tissue levels.
AUTHENTICATION — HPLC Fingerprinting and DNA Testing
Bilberry market historically plagued by adulteration with cheaper bilberry-related species; Indena's HPLC fingerprinting and DNA testing verifies authentic Vaccinium myrtillus identity.
Circular Economy / Zero-Waste Production
All fruit waste, water, ethanol used are upcycled and reused; investments in highly efficient energy production (solar, steam boilers); 75% energy self-production.
Clinical trials
Multiple bilberry extract RCTs for visual function, contrast sensitivity, dry eye.
Adults with eye health concerns.
Improvements in contrast sensitivity, retinal function, dry eye symptoms. Established Mirtoselect eye health evidence.
Multiple Mirtoselect trials for chronic venous insufficiency and microcirculation.
Adults with venous insufficiency.
Significant improvements in symptoms, capillary integrity, microcirculation markers.
About this ingredient
MIRTOSELECT® is the AUTHENTIC BILBERRY EXTRACT (VACCINIUM MYRTILLUS) developed by INDENA (Italy) — the MOST STUDIED BILBERRY EXTRACT in the market. BILBERRY BACKGROUND: small wild blueberry-like fruit native to NORTHERN AND EASTERN EUROPEAN FORESTS; distinct from American blueberry (V. corymbosum) — bilberries are smaller, darker, more concentrated in anthocyanins.
KEY DISTINCTIONS: (1) ≥36% ANTHOCYANIN standardization; (2) HPLC FINGERPRINTING for authenticity; (3) DNA TESTING verification (anti-adulteration); (4) SUSTAINABLE WILD-HARVEST from Northern/Eastern European forests; (5) CIRCULAR ECONOMY / ZERO-WASTE production; (6) 75% ENERGY SELF-PRODUCTION (solar, steam); (7) Most-studied bilberry extract; (8) Quality standards of pharmaceutical world.
EVIDENCE-BASED USES: (1) VASCULAR HEALTH and microcirculation (foundational); (2) Chronic venous insufficiency; (3) RETINAL HEALTH and dry eye; (4) Contrast sensitivity (visual function); (5) Antioxidant free-radical scavenging; (6) Brain health / emotional wellbeing (recent); (7) Cardiovascular health (modest).
CRITICAL CAUTIONS: (1) BILBERRY ADULTERATION — bilberry market historically plagued by adulteration with cheaper related species (cranberry, etc.) or even synthetic anthocyanins; Indena's authentication (HPLC + DNA) addresses this; verify Mirtoselect® branding; (2) DOSE — 160-320 mg/day; (3) ANTICOAGULANT INTERACTION — modest antiplatelet effects; theoretical bleeding; consult; (4) PREGNANCY — bilberry food safe; concentrated supplementation generally safe; (5) MIRTOSELECT vs OTHER BILBERRY — Indena is the gold standard; verify product specifies Mirtoselect® for clinical evidence alignment; (6) SUSTAINABILITY POSITIONING — wild-harvest supports rural communities (Northern/Eastern Europe); biodiversity protection; verify ethical sourcing; (7) FOR EYE HEALTH — Mirtoselect complementary to lutein/zeaxanthin (FloraGLO + OPTISHARP) — different mechanisms; (8) FOR VASCULAR HEALTH — comprehensive venous insufficiency approach: compression, exercise, weight management, possibly Daflon (diosmin), Mirtoselect; (9) ANTHOCYANIN RICH FOODS — bilberries, blueberries, blackcurrants, açai also contain anthocyanins; supplementation provides concentrated standardized doses; (10) BRAND VERIFICATION — Mirtoselect® is Indena trademark with specific authentication; clinical evidence specific to this branded form; (11) For COMPREHENSIVE EYE/VASCULAR HEALTH — among the best-evidenced bilberry extracts with significant clinical trial history.