Home Ingredients PhytoPin® (French Maritime Pine Bark Extract)
AntioxidantCardiovascular

PhytoPin® (French Maritime Pine Bark Extract)

Pinus pinaster
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

PhytoPin® is a French maritime pine (Pinus pinaster) bark extract standardized for OPCs. These proanthocyanidin antioxidants support healthy circulation, antioxidant defense, and vascular health.

Studied Dose Commonly 100 to 200 mg per day.
Active Compound French maritime pine bark extract rich in oligomeric proanthocyanidins (OPCs).

Benefits

Antioxidant defense

French maritime pine bark is rich in oligomeric proanthocyanidins (OPCs), among the most potent plant antioxidants, protecting cells and blood vessels.

Supported by Trial 1

Circulation and vascular support

Pine bark OPCs are studied for supporting healthy blood-vessel function and circulation, including cardiometabolic markers.

Supported by Trial 1

Skin and recovery support

By countering oxidative stress, pine bark OPCs are also studied for skin and recovery support.

Supported by Trial 1

Mechanism of action

1

OPC antioxidant action

Pine bark proanthocyanidins scavenge free radicals and support the body's antioxidant enzymes, protecting blood vessels and tissues.

2

Nitric-oxide support

Pine bark OPCs support nitric-oxide-mediated blood-vessel relaxation, aiding healthy circulation.

Clinical trials

1
Pine Bark (Pycnogenol) and Cardiometabolic Health — Meta-Analysis
PubMed

Systematic review and meta-analysis of pycnogenol (French maritime pine bark) on cardiometabolic health. (Malekahmadi et al. 2019, Pharmacological Research)

Adults across multiple trials.

Pine bark extract supported cardiometabolic markers; the authors noted that larger trials are warranted.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED.
Mild digestive upset or dizziness is occasionally reported.
Take with food.

Important Drug interactions

Anticoagulants — OPCs may have a mild additive effect; monitor.
Blood pressure medication — possible additive effect; monitor.
Tell your doctor before surgery.

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Frequently asked questions about PhytoPin® (French Maritime Pine Bark Extract)

What is PhytoPin® (French Maritime Pine Bark Extract)?

PhytoPin® is a French maritime pine (Pinus pinaster) bark extract standardized for OPCs. These proanthocyanidin antioxidants support healthy circulation, antioxidant defense, and vascular health.

What is the recommended dosage of PhytoPin® (French Maritime Pine Bark Extract)?

The clinically studied dose for PhytoPin® (French Maritime Pine Bark Extract) is Commonly 100 to 200 mg per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is PhytoPin® (French Maritime Pine Bark Extract) used for?

PhytoPin® (French Maritime Pine Bark Extract) is studied for antioxidant defense, circulation and vascular support, skin and recovery support. French maritime pine bark is rich in oligomeric proanthocyanidins (OPCs), among the most potent plant antioxidants, protecting cells and blood vessels.

Are there side effects from taking PhytoPin® (French Maritime Pine Bark Extract)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED. Mild digestive upset or dizziness is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is PhytoPin® (French Maritime Pine Bark Extract) safe to take?

Whether PhytoPin® (French Maritime Pine Bark Extract) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED. It may also interact with certain medications. PhytoPin® (French Maritime Pine Bark Extract) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Malekahmadi M, Moradi Moghaddam O, Firouzi S, et al. Effects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res. 2019;150:104472..PubMedUsed to support: Meta-analysis supporting cardiometabolic benefit of French maritime pine bark OPCs (the active in this branded extract).