Benefits
Blood Glucose Support
Pterocarpus marsupium has long Ayurvedic use for blood glucose management ('madhumeha' — Ayurvedic term for diabetes-like conditions); modern research supports.
Pterostilbene Bioactive
Pterostilbene is a resveratrol-like compound with potential metabolic, antioxidant, and longevity effects; Silbinol contains naturally.
Pancreatic Beta-Cell Support
Some research suggests Pterocarpus supports pancreatic beta-cell function — relevant to type 2 diabetes management.
Metabolic Health Adjunct
Combined polyphenol profile supports metabolic markers including insulin sensitivity, lipid profile.
Patented Sabinsa Standardization
Sabinsa's patented Silbinol standardization ensures consistent active compound delivery.
Mechanism of action
Pterostilbene Activity
Pterostilbene is methylated form of resveratrol with better bioavailability and similar (some say superior) bioactivity; effects on metabolism, antioxidant defense, sirtuin pathways.
Insulin Sensitization (Modest)
Pterocarpus extracts modestly enhance insulin sensitivity in animal and clinical research.
Pancreatic Beta-Cell Effects
Some research suggests Pterocarpus supports pancreatic beta-cell function and possibly regeneration.
Antioxidant Polyphenol Activity
Multiple polyphenols provide antioxidant defense relevant to diabetic oxidative stress.
Clinical trials
Indian Council of Medical Research multicenter trial of Pterocarpus marsupium for type 2 diabetes.
Type 2 diabetes patients.
Modest improvements in fasting and postprandial glucose. Established Pterocarpus diabetes evidence.
Sabinsa clinical studies of Silbinol for metabolic applications.
Adults with metabolic concerns.
Glucose and metabolic marker improvements.
About this ingredient
SILBINOL® is a STANDARDIZED PTEROCARPUS MARSUPIUM (INDIAN KINO TREE) heartwood extract developed by SABINSA CORPORATION. PTEROCARPUS BACKGROUND: tropical tree native to India, Sri Lanka, Nepal; heartwood used in AYURVEDA for over 2,000 years for 'MADHUMEHA' (diabetes-like conditions); also called 'Indian Kino' for the red gum (kino) it produces.
KEY ACTIVES: PTEROSTILBENE (methylated resveratrol analog), pterocarpus polyphenols.
KEY DISTINCTIONS: (1) PATENTED Sabinsa standardization; (2) PTEROSTILBENE-CONTAINING; (3) Long Ayurvedic + modern research; (4) Self-affirmed GRAS; (5) Sabinsa quality standards.
EVIDENCE-BASED USES: (1) Blood glucose support; (2) Metabolic health; (3) Pancreatic beta-cell support; (4) Antioxidant (pterostilbene); (5) Diabetes management adjunct.
CRITICAL CAUTIONS: (1) DIAGNOSED DIABETES — Silbinol is ADJUNCT to medical management, not replacement; consult endocrinologist; monitor glucose; (2) DIABETES MEDICATIONS — additive hypoglycemic effects; medication adjustment may be needed; (3) HYPOGLYCEMIA RISK — caution combining with insulin or sulfonylureas; (4) DOSE — per Sabinsa specification; (5) PREGNANCY — limited safety data; AVOID; (6) PTEROSTILBENE vs RESVERATROL — pterostilbene is methylated resveratrol with better bioavailability; emerging research suggests similar or superior effects in some applications; (7) SILBINOL vs OTHER BLOOD GLUCOSE INGREDIENTS — alternatives include chromium (ChromeMate), berberine, alpha-lipoic acid, cinnamon; different mechanisms; complementary; (8) AYURVEDIC MADHUMEHA — Ayurveda recognized diabetes-like conditions millennia ago; long traditional botanical research; modern science validates many traditional uses; (9) FOR COMPREHENSIVE METABOLIC HEALTH — diet (especially carbohydrate quality), exercise, weight management, sleep, stress management, metformin/medications when warranted, supplements adjunct; (10) BRAND VERIFICATION — Silbinol® is Sabinsa trademark; specific patented standardization; clinical evidence on this branded form; (11) PTEROSTILBENE FOOD SOURCES — small amounts in blueberries; Silbinol provides concentrated form; (12) For DIABETES MANAGEMENT — comprehensive approach essential; supplements one component.