Home Top Picks Metabolic Health
Metabolic Health

Best metabolic health
supplements.

Support blood sugar regulation, insulin sensitivity, lipid balance, and cellular energy metabolism — critical for managing metabolic syndrome and related conditions.

130
Ingredients
350
Clinical trials
3
Trending now
🏆 Evidence Ranked
Top Metabolic Health Supplements
Ranked by evidence level, then number of clinical trials.
#1 Pick
Metabolic Health
Magnesium
Magnesium is the fourth most abundant mineral in the body and a cofactor for over 300 enzymatic reactions. It plays foundational roles in mu…
Very Strong
6 trials
#2 Pick
Metabolic Health
Niacin
Niacin, or vitamin B3, is a vital nutrient that supports energy production by serving as a precursor to coenzymes NAD and NADP, which are es…
Very Strong
5 trials
#3 Pick
Metabolic Health
Pycnogenol® (French Maritime Pine Bark)
Pycnogenol® (Horphag Research) is a standardized extract from the bark of French maritime pine trees grown along the Landes coast of southwe…
Very Strong
5 trials
#4 Pick
Metabolic Health
DeltaGold® (Annatto Tocotrienols — American River Nutrition)
DeltaGold® is the FIRST AND ONLY TOCOPHEROL-FREE TOCOTRIENOL ingredient from American River Nutrition (Everwell Health subsidiary) — derived…
Very Strong
3 trials
#5 Pick
Metabolic Health
Psyllium Husk (Plantago ovata)
Psyllium husk is the soluble fiber derived from the seed husks of Plantago ovata — the most widely sold dietary fiber supplement globally an…
Very Strong
2 trials
📈 Trending Now
Fastest Growing Metabolic Health Ingredients
Ingredients seeing rapid growth in research interest and formulator adoption in 2024–2025.
Trending
Metabolic Health
BioPerine® (Black Pepper Extract — Sabinsa)
BioPerine® is the branded standardized black pepper extract from Sabinsa Corporation (US/India) — the most clinically researched piperine pr…
Strong
3 trials
Trending
Metabolic Health
Capsaicin / Capsicum Extract (Capsimax®)
Capsaicin is the primary bioactive compound in hot peppers, responsible for their heat and their powerful thermogenic, metabolic, and analge…
Strong
3 trials
Trending
Metabolic Health
ThymoQuin® (Black Seed Oil — TriNutra)
ThymoQuin® is the branded black seed oil from TriNutra (Israel) — standardized to ≥3% thymoquinone content with documented clinical trial ev…
Strong
3 trials
🔬 Emerging Research
Future Metabolic Health Ingredients to Watch
Lower evidence now but active research underway — these may become top picks within 2–3 years.
Watch
Metabolic Health
Acacia Fiber (inavea™ Pure Acacia)
Acacia fiber (gum arabic) is a natural soluble dietary fiber harvested from the sap of Acacia senegal and Acacia seyal trees grown in the Sa…
Moderate
3 trials
Watch
Metabolic Health
Aged Black Garlic ABG10+® (Pharmactive)
Aged Black Garlic ABG10+® (Pharmactive, Spain) is a standardized aged black garlic extract. Aging fresh garlic at controlled temperature and…
Moderate
3 trials
Watch
Metabolic Health
Glavonoid® / Kaneka Glavonoid™ (Licorice Flavonoid Oil)
Branded licorice flavonoid oil (LFO) from Kaneka Corporation (Japan). Composition: 30% licorice ethanolic extract dissolved in medium-chain…
Moderate
3 trials
Watch
Metabolic Health
Morosil® (Moro Red Orange Extract)
Standardized extract from Sicilian Moro red blood orange juice. Studied at 400 mg/day for body composition support — body weight, BMI, waist…
Moderate
3 trials
All Ingredients
All 130 Metabolic Health Supplements
Complete list, sorted by evidence strength.
Metabolic Health
Magnesium
Magnesium is the fourth most abundant mineral in the body and a cofactor for over 300 enzymatic reactions. It plays foundational roles in mu…
Very Strong
6 trials
Metabolic Health
Niacin
Niacin, or vitamin B3, is a vital nutrient that supports energy production by serving as a precursor to coenzymes NAD and NADP, which are es…
Very Strong
5 trials
Metabolic Health
Pycnogenol® (French Maritime Pine Bark)
Pycnogenol® (Horphag Research) is a standardized extract from the bark of French maritime pine trees grown along the Landes coast of southwe…
Very Strong
5 trials
Metabolic Health
DeltaGold® (Annatto Tocotrienols — American River Nutrition)
DeltaGold® is the FIRST AND ONLY TOCOPHEROL-FREE TOCOTRIENOL ingredient from American River Nutrition (Everwell Health subsidiary) — derived…
Very Strong
3 trials
Metabolic Health
Psyllium Husk (Plantago ovata)
Psyllium husk is the soluble fiber derived from the seed husks of Plantago ovata — the most widely sold dietary fiber supplement globally an…
Very Strong
2 trials
Metabolic Health
Ashwagandha
Ashwagandha is an adaptogenic herb that may reduce stress, enhance mood, and support overall vitality by modulating the body's response to p…
Strong
7 trials
Metabolic Health
Berberine
Berberine is a bioactive compound extracted from plants like barberry and goldenseal, known for its antimicrobial, anti-inflammatory, and me…
Strong
6 trials
Metabolic Health
Beta-Glucans (Oat & Yeast-Derived)
Beta-glucans are soluble polysaccharide fibers from oats, barley, baker's yeast (Saccharomyces cerevisiae), and medicinal mushrooms. Critica…
Strong
5 trials
Metabolic Health
Ginger (Zingiber officinale)
Ginger is one of the most widely consumed spices and medicinal plants globally, with over 5,000 years of documented use in Ayurvedic, Tradit…
Strong
5 trials
Metabolic Health
Thiamine
Thiamine, also known as vitamin B1, is a water-soluble vitamin essential for converting carbohydrates into energy and supporting nervous sys…
Strong
5 trials
Metabolic Health
Vitamin B6 (Pyridoxine)
Vitamin B6 (pyridoxine) is a water-soluble vitamin essential for amino acid metabolism, neurotransmitter synthesis, and red blood cell forma…
Strong
5 trials
Metabolic Health
Erythritol
Erythritol is a 4-carbon sugar alcohol (polyol) — about 60-70% as sweet as sucrose with essentially zero calories. Naturally produced via ye…
Strong
4 trials
Metabolic Health
Nicotinamide Riboside
Nicotinamide Riboside (NR) is a vitamin B3 derivative that serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), the central co…
Strong
4 trials
Metabolic Health
Pantothenic Acid
Pantothenic acid, or vitamin B5, is a water-soluble vitamin essential for synthesizing coenzyme A, which supports energy metabolism by break…
Strong
4 trials
Metabolic Health
Resistant Starch
Starch fraction that escapes small intestine digestion and reaches the colon for fermentation. Produces butyrate and other SCFAs, supports g…
Strong
4 trials
Metabolic Health
Stevia (Stevia rebaudiana)
Stevia (Stevia rebaudiana) is a South American plant whose leaves contain steviol glycosides (rebaudioside A, stevioside) — natural high-int…
Strong
4 trials
Metabolic Health
Sucralose
Sucralose (marketed as Splenda®) is a chlorinated sucrose derivative — about 600 times sweeter than sugar with zero calories. FDA-approved a…
Strong
4 trials
Metabolic Health
Xylitol
Xylitol is a 5-carbon sugar alcohol (polyol) that occurs naturally in birch bark, corn cobs, and many fruits/vegetables. Used commercially a…
Strong
4 trials
Metabolic Health
Alpha Lipoic Acid
Alpha lipoic acid (ALA) is a naturally occurring organosulfur compound and universal antioxidant active in both fat-soluble and water-solubl…
Strong
3 trials
Metabolic Health
BioPerine® (Black Pepper Extract — Sabinsa)
BioPerine® is the branded standardized black pepper extract from Sabinsa Corporation (US/India) — the most clinically researched piperine pr…
Strong
3 trials
Metabolic Health
Black Seed Oil
Black Seed Oil is extracted from Nigella sativa seeds (also called black cumin, kalonji, or 'the seed of blessing' in traditional Middle Eas…
Strong
3 trials
Metabolic Health
Capsaicin / Capsicum Extract (Capsimax®)
Capsaicin is the primary bioactive compound in hot peppers, responsible for their heat and their powerful thermogenic, metabolic, and analge…
Strong
3 trials
Metabolic Health
Citrus Bergamot (Citrus bergamia)
Citrus bergamot (Citrus bergamia) is a sour orange variety grown almost exclusively in the Calabria region of southern Italy, containing a u…
Strong
3 trials
Metabolic Health
Gynostemma pentaphyllum (Jiaogulan / Southern Ginseng)
Gynostemma pentaphyllum (also called Jiaogulan or Southern Ginseng) is a traditional Chinese herb with growing modern clinical evidence for…
Strong
3 trials
Metabolic Health
Oat Bran (Beta-Glucan)
Outer layer of oat groat — concentrated source of beta-glucan soluble fiber (~5-7% by weight). Beta-glucan ≥3 g/day reduces LDL cholesterol…
Strong
3 trials
Metabolic Health
Sulforaphane / Glucoraphanin
Sulforaphane is one of the most potent natural NRF2 activators discovered — a sulfur-containing compound formed when glucoraphanin (the prec…
Strong
3 trials
Metabolic Health
ThymoQuin® (Black Seed Oil — TriNutra)
ThymoQuin® is the branded black seed oil from TriNutra (Israel) — standardized to ≥3% thymoquinone content with documented clinical trial ev…
Strong
3 trials
Metabolic Health
Witholytin® (Olive Leaf Extract — Verdure Sciences)
Witholytin® is a branded standardized olive leaf extract from Verdure Sciences (Indiana, USA), distinguished by consistent oleuropein conten…
Strong
3 trials
Metabolic Health
BarliV™ (Barley Beta-Glucan — Cargill)
BarliV™ is a BARLEY BETA-GLUCAN ingredient from Cargill — distinguished by water-soluble beta-glucan from barley with FDA-approved health cl…
Strong
2 trials
Metabolic Health
BioBerb® (Bioavailable Berberine — Saanroo)
BioBerb® is Saanroo's branded bioavailable berberine formulation — addressing the key clinical limitation of standard berberine: very poor o…
Strong
2 trials
Metabolic Health
Black Pepper Extract
Black pepper extract is derived from Piper nigrum and contains piperine — the alkaloid responsible for black pepper's pungent taste and its…
Strong
2 trials
Metabolic Health
Capsifen® (Bioavailable Capsaicinoids via FenuMat® — Akay Bioactives)
Capsifen® is Akay Bioactives' red chili (Capsicum annum) capsaicinoid complex delivered via FenuMat® technology — fenugreek galactomannan be…
Strong
2 trials
Metabolic Health
Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)
Capsimax® is a branded encapsulated capsicum extract from OmniActive, providing standardized capsaicinoids (the active compounds from chili…
Strong
2 trials
Metabolic Health
Choline
Choline is an essential nutrient and precursor to acetylcholine (the primary learning and memory neurotransmitter) and phosphatidylcholine (…
Strong
2 trials
Metabolic Health
Flaxseed / Flaxseed Oil (Linum usitatissimum)
Flaxseed (linseed) is one of the richest plant sources of alpha-linolenic acid (ALA, omega-3), lignans (phytoestrogens), and soluble fiber —…
Strong
2 trials
Metabolic Health
Glucomannan (Konjac Root Fiber)
Glucomannan is a water-soluble dietary fiber derived from the root of the konjac plant (Amorphophallus konjac), with the highest viscosity a…
Strong
2 trials
Metabolic Health
Greenselect® Phytosome (Decaffeinated Green Tea Catechin Phytosome — Indena)
Greenselect® Phytosome is Indena's phytosome-formulated decaffeinated green tea extract — addressing the well-documented poor oral bioavaila…
Strong
2 trials
Metabolic Health
Inositol (Myo-Inositol)
Inositol is a naturally occurring sugar alcohol acting as a secondary messenger in insulin signaling and critical for cell membrane structur…
Strong
2 trials
Metabolic Health
L-Carnitine
L-Carnitine is a naturally-occurring amino acid derivative essential for fatty acid metabolism — specifically, transporting long-chain fatty…
Strong
2 trials
Metabolic Health
Manganese
Manganese is an essential trace mineral and cofactor for over 300 enzymes — most notably manganese superoxide dismutase (MnSOD), the primary…
Strong
2 trials
Metabolic Health
Olive Leaf Extract
Olive leaf extract is derived from Olea europaea leaves and contains oleuropein — the bitter polyphenol responsible for many of the cardiova…
Strong
2 trials
Metabolic Health
R-Lipoic Acid (Natural / Stabilized R-ALA)
R-Lipoic Acid (R-ALA) is the BIOLOGICALLY ACTIVE ENANTIOMER of alpha-lipoic acid — the naturally occurring form in mitochondria. Distinct fr…
Strong
2 trials
Metabolic Health
Selenium
Selenium is an essential trace mineral that functions as a critical component of selenoproteins, including glutathione peroxidase enzymes th…
Strong
2 trials
Metabolic Health
Soy Isoflavones (Glycine max)
Soy isoflavones — primarily genistein, daidzein, and glycitein — are phytoestrogens found in soybeans that bind estrogen receptors with sele…
Strong
2 trials
Metabolic Health
Svetol® (Decaffeinated Green Coffee Extract — Givaudan/Naturex)
Svetol® is a branded decaffeinated green coffee bean (Coffea canephora robusta) extract from Givaudan (formerly Naturex), standardized to ≥4…
Strong
2 trials
Metabolic Health
Chromax® (Chromium Picolinate)
Chromax® (Nutrition21) is the most clinically studied form of chromium — chromium picolinate — with over 35 human clinical studies supportin…
Strong
1 trial
Metabolic Health
Biotin
Biotin, also known as vitamin B7, is a water-soluble vitamin that supports healthy hair, skin, and nails while aiding in energy metabolism…
Moderate
7 trials
Metabolic Health
Taurine
Taurine is a sulfur-containing amino acid found in high concentrations in the heart, brain, and muscles, supporting cellular function, energ…
Moderate
7 trials
Metabolic Health
Chromium
Chromium is an essential trace mineral that plays a key role in regulating blood sugar by enhancing the effects of insulin, making it import…
Moderate
5 trials
Metabolic Health
Inulin
Chicory root inulin is a soluble fiber and prebiotic that supports gut health by promoting beneficial bacteria, improving digestion, and rel…
Moderate
5 trials
Metabolic Health
Salacia (Salacinol)
Ayurvedic plant genus (Kothala himbutu) with α-glucosidase inhibitor activity. Multiple RCTs show reduced postprandial glucose and insulin s…
Moderate
5 trials
Metabolic Health
Banaba Leaf (Lagerstroemia speciosa)
Banaba leaf is a Southeast Asian medicinal plant traditionally used for diabetes management. Its principal bioactives — corosolic acid and e…
Moderate
4 trials
Metabolic Health
Neem (Azadirachta indica)
Neem is a tree native to the Indian subcontinent, traditionally called the "village pharmacy" in Ayurveda. RCT evidence supports neem mouthw…
Moderate
4 trials
Metabolic Health
Acacia Fiber (inavea™ Pure Acacia)
Acacia fiber (gum arabic) is a natural soluble dietary fiber harvested from the sap of Acacia senegal and Acacia seyal trees grown in the Sa…
Moderate
3 trials
Metabolic Health
Aged Black Garlic ABG10+® (Pharmactive)
Aged Black Garlic ABG10+® (Pharmactive, Spain) is a standardized aged black garlic extract. Aging fresh garlic at controlled temperature and…
Moderate
3 trials
Metabolic Health
Aronia / Chokeberry (Aronia melanocarpa)
Aronia berry (black chokeberry) is one of the most polyphenol-rich fruits known, particularly anthocyanins. Studied for cardiovascular and m…
Moderate
3 trials
Metabolic Health
Capsinoids (Non-Pungent Capsaicin Analogs)
Non-pungent capsaicin analogs from CH-19 Sweet pepper variety — capsiate, dihydrocapsiate, nordihydrocapsiate. Provide thermogenic and metab…
Moderate
3 trials
Metabolic Health
Chlorogenic Acid
Major polyphenolic ester in coffee (especially green/unroasted), mate, blueberries, apples, and prunes. Standard coffee provides ~20-675 mg…
Moderate
3 trials
Metabolic Health
Ellagic Acid
Polyphenol abundant in pomegranates, walnuts, raspberries, and strawberries. Low direct bioavailability — gut microbiota convert to bioactiv…
Moderate
3 trials
Metabolic Health
Glavonoid® / Kaneka Glavonoid™ (Licorice Flavonoid Oil)
Branded licorice flavonoid oil (LFO) from Kaneka Corporation (Japan). Composition: 30% licorice ethanolic extract dissolved in medium-chain…
Moderate
3 trials
Metabolic Health
GlyNAC (Glycine + N-Acetylcysteine)
Combination of GLYCINE and N-ACETYLCYSTEINE developed by Dr. Rajagopal Sekhar at Baylor College of Medicine for aging-related glutathione de…
Moderate
3 trials
Metabolic Health
Lactobacillus gasseri
Lactobacillus gasseri is a lactic acid bacterium native to the human gastrointestinal tract, oral cavity, and breast milk. It has emerged as…
Moderate
3 trials
Metabolic Health
Molecular Hydrogen (H2)
H2 gas with selective antioxidant properties, discovered by Ohsawa 2007 (Nature Medicine). Selectively scavenges hydroxyl radicals and perox…
Moderate
3 trials
Metabolic Health
Morosil® (Moro Red Orange Extract)
Standardized extract from Sicilian Moro red blood orange juice. Studied at 400 mg/day for body composition support — body weight, BMI, waist…
Moderate
3 trials
Metabolic Health
Mythocondro® (Non-Animal Chondroitin Sulfate — Gnosis by Lesaffre)
Mythocondro® is a non-animal chondroitin sulfate from Gnosis by Lesaffre (Italy/France) — produced via fermentation-based biotransformation…
Moderate
3 trials
Metabolic Health
Oligonol® (Lychee + Green Tea Polyphenol — Amino Up)
Oligonol® is a branded low-molecular-weight polyphenol product from Amino Up Chemical Company (Japan), combining 85% lychee fruit (Litchi ch…
Moderate
3 trials
Metabolic Health
Pantesin® (Pantethine — Daiichi Fine Chemical)
Pantesin® is the branded standardized pantethine from Daiichi Fine Chemical (Japan) — the most clinically researched pantethine form used in…
Moderate
3 trials
Metabolic Health
Pleurotus ostreatus (Oyster Mushroom)
Edible oyster mushroom containing naturally occurring mevinolin (lovastatin) — an HMG-CoA reductase inhibitor (Gunde-Cimerman & Cimerman 199…
Moderate
3 trials
Metabolic Health
Resveratrol
Resveratrol is a polyphenolic stilbene found in red wine, grapes, and Japanese knotweed root. It activates sirtuins — the same longevity pat…
Moderate
3 trials
Metabolic Health
White Mulberry (Morus alba)
White mulberry leaf extract is studied for postprandial blood glucose control via α-glucosidase inhibition by 1-deoxynojirimycin (DNJ). Mode…
Moderate
3 trials
Metabolic Health
ActivAMP® (Gynostemma for Healthy Aging)
ActivAMP® is a STANDARDIZED GYNOSTEMMA PENTAPHYLLUM EXTRACT developed by Saanroo (formerly Gencor Pacific) — distinguished by AMPK ACTIVATIO…
Moderate
2 trials
Metabolic Health
Amla / Indian Gooseberry (Capros®)
Amla (Indian gooseberry) is one of the richest natural sources of vitamin C and polyphenols on earth — containing up to 600–700 mg of vitami…
Moderate
2 trials
Metabolic Health
Arabinoxylan (Arrabina®)
Arabinoxylan is a hemicellulose fiber derived from the bran layer of wheat (Triticum aestivum) or other cereal grains, consisting of arabino…
Moderate
2 trials
Metabolic Health
Astragalus (Astragalus membranaceus)
Astragalus (Huang Qi) is one of the most important tonic herbs in Traditional Chinese Medicine, used for over 2,000 years as a fundamental i…
Moderate
2 trials
Metabolic Health
ChromeMate® (Niacin-Bound Chromium — Lonza)
ChromeMate® is a NIACIN-BOUND CHROMIUM COMPLEX (chromium polynicotinate) developed by Lonza — distinguished from chromium picolinate by niac…
Moderate
2 trials
Metabolic Health
Cinnamon (Ceylon vs Cassia)
Cinnamon is the dried inner bark of Cinnamomum trees — two main supplement species: CEYLON (C. verum, 'true cinnamon', sweeter, lower coumar…
Moderate
2 trials
Metabolic Health
Cinnulin® (True Cinnamon for Glucose — Verdure)
Cinnulin® is a PROPRIETARY STANDARDIZED CINNAMON EXTRACT developed by Verdure Sciences — a water-extract of Cinnamomum cassia distinguished…
Moderate
2 trials
Metabolic Health
Eriocitrin / Eriomin® (Lemon Flavonoid)
Eriocitrin is the primary flavanone glycoside found in lemon (Citrus limon) peel and juice, accounting for much of lemon's health-promoting…
Moderate
2 trials
Metabolic Health
Evening Primrose Oil (Oenothera biennis)
Evening primrose oil (EPO) is cold-pressed from the seeds of Oenothera biennis and is one of the richest plant sources of gamma-linolenic ac…
Moderate
2 trials
Metabolic Health
Fenugreek
Fenugreek is an annual plant native to the Mediterranean and South Asia, used for millennia in Ayurvedic and traditional medicine. Its seeds…
Moderate
2 trials
Metabolic Health
Gencinia® (Healthy Cinnamon)
Gencinia® is a STANDARDIZED CINNAMON EXTRACT developed by Saanroo (formerly Gencor Pacific) — designed for metabolic health applications inc…
Moderate
2 trials
Metabolic Health
GlucoVantage® (Dihydroberberine)
GlucoVantage® is NNB Nutrition's patented dihydroberberine (DHB) — the active reduced metabolite of berberine with approximately 5x greater…
Moderate
2 trials
Metabolic Health
Gymnema Sylvestre (Gurmar — 'Sugar Destroyer')
Gymnema sylvestre is an Ayurvedic herb traditionally called 'GURMAR' ('sugar destroyer' in Hindi) — used for over 2,000 years in Indian trad…
Moderate
2 trials
Metabolic Health
Holy Basil (Tulsi)
Holy basil (Tulsi) is a sacred plant in Ayurvedic medicine and one of the most revered adaptogens in Indian traditional healing. Its eugenol…
Moderate
2 trials
Metabolic Health
Maitake Mushroom (Grifola frondosa)
Maitake ('dancing mushroom' in Japanese) is a culinary and medicinal mushroom native to East Asia and North America. Distinguished by its D-…
Moderate
2 trials
Metabolic Health
Metabolaid® (Hibiscus + Lemon Verbena)
Metabolaid® (Monteloeder/SuanNutra) is a patented combination of Hibiscus sabdariffa and Lemon verbena (Lippia citriodora) polyphenols valid…
Moderate
2 trials
Metabolic Health
MitoBurn® (L-BAIBA)
MitoBurn® is NNB Nutrition's patented stabilized form of L-β-aminoisobutyric acid (L-BAIBA) — a myokine naturally produced by skeletal muscl…
Moderate
2 trials
Metabolic Health
Moringa
Moringa oleifera, the 'miracle tree,' is native to South Asia and one of the most nutrient-dense plants known. Its leaves contain complete p…
Moderate
2 trials
Metabolic Health
NMN (Nicotinamide Mononucleotide)
NMN is a direct precursor to NAD+, a coenzyme essential for cellular energy production, DNA repair, and sirtuin activation. NAD+ levels natu…
Moderate
2 trials
Metabolic Health
Pantethine
Pantethine is the biologically active form of pantothenic acid (vitamin B5) — specifically, two pantothenic acid molecules joined by cysteam…
Moderate
2 trials
Metabolic Health
Portusana® (Purslane Extract — Frutarom)
Portusana® (EFLA® 308) is a STANDARDIZED PURSLANE EXTRACT (Portulaca oleracea) developed by Frutarom Health (now IFF) — distinguished from g…
Moderate
2 trials
Metabolic Health
Silbinol® (Pterocarpus marsupium for Glucose — Sabinsa)
Silbinol® is a STANDARDIZED PTEROCARPUS MARSUPIUM (Indian Kino tree) heartwood extract developed by Sabinsa — distinguished by PTEROSTILBENE…
Moderate
2 trials
Metabolic Health
Slendesta® (Potato Protein Extract)
Slendesta® (Kemin Industries) is a standardized extract of protease inhibitor II (PI2) from potato (Solanum tuberosum) — a naturally occurri…
Moderate
2 trials
Metabolic Health
Terminalia Chebula (Rejuna®)
Terminalia chebula (Haritaki, Black myrobalan) is the most revered herb in Tibetan and Ayurvedic medicine — called the 'King of Herbs' in Ti…
Moderate
2 trials
Metabolic Health
ThinOgen® (Fucoxanthin from Brown Seaweed — BGG)
ThinOgen® is a STANDARDIZED FUCOXANTHIN extract from BROWN SEAWEED developed by BGG — distinguished by quality standardization for weight ma…
Moderate
2 trials
Metabolic Health
Tinospora Cordifolia (Tinofend®)
Tinospora cordifolia (Guduchi or Giloy) is a climbing shrub central to Ayurvedic medicine for over 3,000 years, revered as 'Amrita' (divine…
Moderate
2 trials
Metabolic Health
inavea™ CINNAMON ACACIA
inavea™ CINNAMON ACACIA is an ORGANIC SYNERGISTIC FORMULATION developed by Nexira (France) — combining CINNAMON (Cinnamomum verum / cassia)…
Moderate
2 trials
Metabolic Health
Calanus® Oil (Arctic Zooplankton Omega-3 Wax Esters)
Calanus® Oil (Zooca / Aker BioMarine) is a unique omega-3 rich oil from the Arctic copepod Calanus finmarchicus — providing long-chain omega…
Moderate
1 trial
Metabolic Health
Carb10® (Pea Starch Carbohydrate)
Carb10® (Compound Solutions) is a patented, non-GMO pea starch (Pisum sativum) carbohydrate ingredient uniquely characterized by a very low…
Moderate
1 trial
Metabolic Health
Cinnamon FenuMat® (Cinnamon Bark Extract — Akay Bioactives)
Cinnamon FenuMat® is a PATENTED CINNAMON BARK EXTRACT formulated with FENUMAT® technology developed by Akay Bioactives — clinically substant…
Moderate
1 trial
Metabolic Health
Clovinol® (Clove Bud Extract for Metabolic — Akay Bioactives)
Clovinol® is a PROPRIETARY CLOVE BUD EXTRACT (Syzygium aromaticum) developed by Akay Bioactives — clinically substantiated to support metabo…
Moderate
1 trial
Metabolic Health
Ecklonia Cava (Brown Seaweed Polyphenol)
Ecklonia cava is a species of brown kelp seaweed native to the Pacific Ocean coasts of Japan and Korea that contains a unique class of polyp…
Moderate
1 trial
Metabolic Health
Go-Luo® (Monk Fruit Extract — Layn USA)
Go-Luo® is a STANDARDIZED MONK FRUIT EXTRACT (Siraitia grosvenorii) developed by Layn USA — distinguished by being the world's leading brand…
Moderate
1 trial
Metabolic Health
GyngerLean® (Ginger Weight Management Extract)
GyngerLean® (Cepham Inc.) is a standardized ginger (Zingiber officinale) extract specifically developed and clinically studied for weight ma…
Moderate
1 trial
Metabolic Health
InnoSlim® (Stimulant-Free Fat Burning)
InnoSlim® (NuLiv Science) is a patented, stimulant-free fat loss and metabolic health ingredient — the same Astragalus membranaceus and Pana…
Moderate
1 trial
Metabolic Health
Lovia® (Monk Fruit + Stevia Combination — Layn USA)
Lovia® is a UNIQUE COMBINATION of MONK FRUIT and STEVIA developed by Layn USA — distinguished by synergistic sweetener blend that addresses…
Moderate
1 trial
Metabolic Health
Melostacio® (Mango Leaf Extract)
Melostacio® (Botanic Healthcare) is a standardized mango leaf (Mangifera indica) extract providing a concentrated source of mangiferin — a C…
Moderate
1 trial
Metabolic Health
OnoSweet® (Monk Fruit + Allulose Sweetener)
OnoSweet® (Compound Solutions) is a patented natural zero-calorie sweetener system combining monk fruit extract (luo han guo, mogrosides) wi…
Moderate
1 trial
Metabolic Health
SteviUp® M2 (Next-Gen Stevia Reb M — Layn USA)
SteviUp® M2 is a NEXT-GENERATION PLANT-BASED SWEETENER developed by Layn USA via ENZYMATIC CONVERSION of purified steviol glycosides — disti…
Moderate
1 trial
Metabolic Health
Sukré® (Ultra-Pure Allulose)
Sukré® (Compound Solutions) is an ultra-pure allulose (D-psicose) sweetener — a rare monosaccharide found naturally in trace amounts in figs…
Moderate
1 trial
Metabolic Health
Trpti™ (Bioavailable OEA for Metabolic/Gut Health)
Trpti™ is a BIOAVAILABLE FORM OF OLEOYLETHANOLAMIDE (OEA) developed by Saanroo (formerly Gencor Pacific). OEA is a naturally-occurring fatty…
Moderate
1 trial
Metabolic Health
Vitosa® (Next Generation Stevia — BGG)
Vitosa® is BGG's NEXT-GENERATION STEVIA ingredient — distinguished from generic stevia by quality optimization for taste profile and functio…
Moderate
1 trial
Metabolic Health
iXOS® (Xylooligosaccharides Prebiotic)
iXOS® (Compound Solutions) is a patented xylooligosaccharide (XOS) prebiotic fiber derived from non-GMO corn cobs — providing one of the mos…
Moderate
1 trial
Metabolic Health
Akkermansia muciniphila
Akkermansia muciniphila is a gram-negative anaerobic bacterium that lives in the gut mucus layer and degrades mucin into short-chain fatty a…
Limited
5 trials
Metabolic Health
Chlorella
Chlorella is a single-celled freshwater green algae rich in chlorophyll, complete protein (~60% by weight), B vitamins, iron, and Chlorella…
Limited
5 trials
Metabolic Health
Beef Pancreas (Desiccated)
Beef pancreas is unique among organ supplements for its natural digestive enzyme content — providing lipase, protease (trypsin, chymotrypsin…
Limited
3 trials
Metabolic Health
Glabridin (Licorice Isoflavone)
Glabridin is an isoflavonoid specific to Glycyrrhiza glabra L. (licorice root) — distinct from glycyrrhizin (the licorice compound that caus…
Limited
3 trials
Metabolic Health
Myricetin
Flavonol abundant in walnuts, berries (cranberries, blueberries), red wine, tea. Major dietary source: 1-4 mg/day average intake. Strong epi…
Limited
3 trials
Metabolic Health
Trehalose
Natural disaccharide (two glucoses joined α-1,1) found in mushrooms, yeast, and certain plants. Studied as autophagy inducer for neurodegene…
Limited
3 trials
Metabolic Health
Tributyrin (CoreBiome® Butyrate Prodrug)
Tributyrin is a triglyceride of three butyrate molecules on a glycerol backbone — a butyrate prodrug that resists gastric acid and is hydrol…
Limited
3 trials
Metabolic Health
Ursolic Acid
Pentacyclic triterpenoid found in apple peel, holy basil, oregano, rosemary, loquat, and many medicinal plants. Generated enormous interest…
Limited
3 trials
Metabolic Health
Xanthigen® (Fucoxanthin + Pomegranate Seed Oil)
Branded patented blend from Nektium of wakame brown seaweed (Undaria pinnatifida) extract containing fucoxanthin plus pomegranate seed oil…
Limited
3 trials
Metabolic Health
Yacon Syrup
Yacon syrup is a low-glycemic sweetener from the Andean yacon root, rich in fructooligosaccharides (FOS). Modest evidence supports benefits…
Limited
3 trials
Metabolic Health
Aloe Vera (Aloe barbadensis miller)
Aloe vera is a succulent plant whose gel (from the inner leaf) and latex (from the leaf skin) have been used medicinally for over 5,000 year…
Limited
2 trials
Metabolic Health
Bitter Melon (Momordica charantia)
Bitter melon (also called bitter gourd, karela) is a tropical vine fruit used as both food and medicine across South Asia, Africa, and the C…
Limited
2 trials
Metabolic Health
Chromium Polynicotinate (Niacin-Bound Chromium)
Chromium polynicotinate is chromium bound to niacin (vitamin B3 / nicotinic acid) — distinct from chromium picolinate (which uses picolinic…
Limited
2 trials
Metabolic Health
Naringenin
Naringenin is a citrus flavanone found primarily in grapefruit, oranges, and tomatoes. The aglycone form of naringin (the bitter compound in…
Limited
2 trials
Metabolic Health
Fucoxanthin
Fucoxanthin is a marine carotenoid found abundantly in edible brown seaweeds (wakame, hijiki, kombu) that has attracted significant research…
Limited
1 trial
Metabolic Health
Metabolyte® (BHB Energy + B-Vitamins)
Metabolyte® (Compound Solutions) is a patented combination of beta-hydroxybutyrate (BHB) ketone salts and B-vitamins specifically formulated…
Limited
1 trial
Metabolic Health
Vanadium (Vanadyl Sulfate)
Vanadium is a trace element with no established essential function in humans — though insulin-mimetic properties of vanadyl sulfate and orga…
Limited
1 trial