Cardiovascular and heart function improvement
A clinical study in prediabetic women confirmed Calanus® Oil supplementation significantly improved diastolic heart function markers and cardiovascular health parameters vs. placebo. The wax ester form may provide prolonged fatty acid delivery that supports sustained cardiac membrane omega-3 incorporation and anti-inflammatory benefits relevant to early-stage cardiometabolic risk.
Metabolic health in prediabetic populations
Calanus® Oil demonstrated improvements in metabolic health markers in prediabetic women — including blood lipid profiles, insulin sensitivity markers, and inflammatory cytokines — suggesting cardio-metabolic benefits relevant for the large prediabetic population at elevated cardiovascular risk where omega-3 supplementation is most relevant.
Sustainable Arctic source with natural astaxanthin
Calanus finmarchicus copepods are the most abundant marine organism on Earth (by biomass), making Calanus® Oil among the most sustainable omega-3 sources available — requiring no fish catch reduction and with a dramatically lower environmental footprint than fish oil. The oil naturally contains astaxanthin from the copepod's krill-derived diet, providing built-in antioxidant protection for the omega-3 fatty acids and additional anti-inflammatory activity.
Wax ester omega-3 delivery and membrane integration
Calanus® Oil wax esters (fatty acid + fatty alcohol ester linkage) require pancreatic lipase and cholesterol esterase for hydrolysis — a different digestive pathway than triglyceride omega-3s. This wax ester absorption pathway may provide more gradual, sustained fatty acid release into circulation compared to rapid triglyceride hydrolysis. Once absorbed, EPA from Calanus® Oil incorporates into cell membrane phospholipids, replacing pro-inflammatory arachidonic acid in immune cell membranes and shifting eicosanoid production toward anti-inflammatory resolvins and protectins rather than inflammatory prostaglandins.
Clinical study examining Calanus® Oil supplementation effects on cardiovascular function, diastolic blood pressure, and metabolic markers in prediabetic women.
Prediabetic women. Randomized controlled study design.
Calanus® Oil supplementation significantly improved diastolic heart function and cardiometabolic health markers vs. placebo in prediabetic women. Unique wax ester omega-3 benefits confirmed in clinical assessment. Research from Aker BioMarine and Zooca.