EnduBerry™ Nu (Haskap / Blue Honeysuckle Berry)

Lonicera caerulea
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

EnduBerry™ Nu is Mibelle Biochemistry's oral haskap (blue honeysuckle berry, Lonicera caerulea) extract, standardized for anthocyanins (notably cyanidin-3-O-glucoside) and positioned for endurance and exercise performance. Its branded trial was a randomized, double-blind, placebo-controlled crossover in recreational runners showing improved running performance. Honest framing: a small crossover study, manufacturer-associated, so the endurance benefit is promising but not yet broadly replicated.

Studied Dose The branded crossover trial used a single haskap-berry dose before exercise; typical use is a standardized capsule/powder serving before activity. Take with water.
Active Compound Anthocyanin-rich haskap berry (Lonicera caerulea) powder, with cyanidin-3-O-glucoside as the key marker. EnduBerry™ Nu is manufactured by Mibelle Biochemistry.

Benefits

Improved endurance running performance (branded crossover RCT)

In a randomized, double-blind, placebo-controlled crossover in recreational runners, haskap-berry intake improved running performance versus placebo. A small crossover, so encouraging but not definitive.

Anthocyanin antioxidant support during exercise

Haskap is exceptionally rich in anthocyanins, which buffer exercise-induced oxidative stress and may support blood flow — the proposed basis for the performance signal.

Cardiovascular and metabolic antioxidant background

Blue honeysuckle/haskap anthocyanins share the antioxidant and vascular benefits of other dark-berry polyphenols, supporting general antioxidant intake.

Mechanism of action

1

Anthocyanin antioxidant activity

Cyanidin-based anthocyanins scavenge reactive oxygen species generated during exertion and support nitric-oxide-mediated vasodilation, improving oxygen delivery to working muscle.

2

Polyphenol vascular signaling

Berry polyphenols modulate endothelial function and blood flow, a plausible route to improved endurance performance.

Clinical trials

1
Haskap Berry Endurance Running Crossover RCT

Randomized, double-blind, placebo-controlled crossover in recreational runners (Nutrients, 2022).

Recreational male runners

Haskap-berry supplementation improved endurance running performance versus placebo. Small crossover design; manufacturer-associated.

Side effects and drug interactions

Common Potential side effects

Generally very well tolerated; haskap is an edible berry.
Mild gastrointestinal upset possible with concentrated anthocyanin intake.
Harmless reddish tint to stool/urine can occur with high anthocyanin intake.
Allergy to berries is rare but possible.

Important Drug interactions

Anticoagulants/antiplatelets: high-dose anthocyanins carry a theoretical mild bleeding-risk interaction.
Generally a low-interaction, food-derived profile.

Frequently asked questions about EnduBerry™ Nu (Haskap / Blue Honeysuckle Berry)

What is EnduBerry Nu?

EnduBerry Nu is an oral haskap (blue honeysuckle berry) extract from Mibelle, rich in anthocyanins and taken to support endurance and exercise performance. A placebo-controlled crossover trial in runners found improved running performance.

How strong is the evidence?

Promising but early. The branded trial was a small, manufacturer-associated crossover study, so it supports rather than proves an endurance benefit; the anthocyanin antioxidant rationale is well established.

What is EnduBerry Nu used for?

EnduBerry Nu is researched primarily for Athletic Performance, Antioxidant, and Energy. In a randomized, double-blind, placebo-controlled crossover in recreational runners, haskap-berry intake improved running performance versus placebo. A small crossover, so encouraging but not definitive.

What is the recommended dosage of EnduBerry Nu?

The clinically studied dose is The branded crossover trial used a single haskap-berry dose before exercise; typical use is a standardized capsule/powder serving before activity. Take with water. Always follow the product label and check with a healthcare provider for personal advice.

Is EnduBerry Nu safe, and does it have side effects?

For most healthy adults, EnduBerry Nu is well tolerated at studied doses. Reported effects can include: Generally very well tolerated; haskap is an edible berry. Mild gastrointestinal upset possible with concentrated anthocyanin intake. It may also interact with some medications. EnduBerry Nu is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does EnduBerry Nu interact with any medications?

Possible interactions include: Anticoagulants/antiplatelets: high-dose anthocyanins carry a theoretical mild bleeding-risk interaction. Generally a low-interaction, food-derived profile. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for EnduBerry Nu?

NutraSmarts rates the evidence for EnduBerry Nu as Moderate (3 out of 5). It is backed by 1 clinical trial and 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Howatson G, Snaith GC, Kimble R, Cowper G, Keane KM Improved Endurance Running Performance Following Haskap Berry (Lonicera caerulea L.) Ingestion. Nutrients. 2022;14(4). doi: 10.3390/nu14040780.PubMedUsed to support: The branded EnduBerry Nu trial: a randomized, double-blind, placebo-controlled crossover in recreational runners; haskap-berry intake improved endurance running performance versus placebo. Manufacturer-associated; a small crossover, so encouraging rather than definitive.
  2. Jurja S, Negreanu-Pirjol T, Mehedinti MC, Hincu MA, Negreanu-Pirjol BS, Roncea FN, et al. Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention. Nutrients. 2025;17(24). doi: 10.3390/nu17243888.PubMedUsed to support: A 2025 review of blueberry and honeysuckle (haskap) anthocyanin-rich polyphenols, providing background on the bioactives behind EnduBerry Nu's antioxidant and performance rationale.