Home Top Picks Athletic Performance
Athletic Performance

Best athletic performance
supplements.

Clinically validated to improve strength, power, endurance, and recovery. Includes IOC-recognized ergogenic aids and emerging compounds with compelling research.

46
Ingredients
161
Clinical trials
4
Trending now
šŸ† Evidence Ranked
Top Athletic Performance Supplements
Ranked by evidence level, then number of clinical trials.
#1 Pick
Energy
Caffeine
Caffeine, a natural stimulant found in coffee, tea, and other plants, is commonly supplemented in forms like cā€¦
Very Strong
8 trials
#2 Pick
Muscle & Recovery
Creatine
Creatine is a natural compound that enhances muscle strength, power, and growth by boosting energy productionā€¦
Very Strong
6 trials
#3 Pick
Muscle & Recovery
Whey Concentrate
Whey Protein Concentrate (WPC) is a high-quality protein supplement derived from milk during cheese productionā€¦
Very Strong
5 trials
#4 Pick
Cardiovascular
PycnogenolĀ® (French Maritime Pine Bark)
PycnogenolĀ® (Horphag Research) is a standardized extract from the bark of French maritime pine trees grown aloā€¦
Very Strong
4 trials
#5 Pick
Energy
Iron
Iron is an essential trace mineral and a central component of hemoglobin, enabling red blood cells to carry oxā€¦
Very Strong
2 trials
šŸ“ˆ Trending Now
Fastest Growing Athletic Performance Ingredients
Ingredients seeing rapid growth in research interest and formulator adoption in 2024ā€“2025.
Trending
Muscle & Recovery
Creatine
Creatine is a natural compound that enhances muscle strength, power, and growth by boosting energy productionā€¦
Very Strong
6 trials
Trending
Athletic Performance
Tongkat Ali (LJ100Ā®)
Tongkat Ali (Longjack) is a flowering plant native to Southeast Asia whose root has been used for centuries inā€¦
Strong
3 trials
Trending
Athletic Performance
Betaine / TMG (Trimethylglycine)
Betaine (trimethylglycine, TMG) is a naturally occurring compound found in beets, spinach, and whole grains thā€¦
Moderate
2 trials
Trending
Athletic Performance
Sodium Bicarbonate (Baking Soda)
Sodium bicarbonate (baking soda, NaHCOā‚ƒ) is one of the oldest and most studied ergogenic aids in sports sciencā€¦
Strong
2 trials
šŸ”¬ Emerging Research
Future Athletic Performance Ingredients to Watch
Lower evidence now but active research underway ā€” these may become top picks within 2ā€“3 years.
Emerging
Muscle & Recovery
HMB (Beta-Hydroxy Beta-Methylbutyrate)
Beta-hydroxy beta-methylbutyrate (HMB) is a metabolite of the essential amino acid leucine ā€” produced when leuā€¦
Moderate
2 trials
All Ingredients
All 46 Athletic Performance Supplements
Complete list, sorted by evidence strength.
Energy
Caffeine
Caffeine, a natural stimulant found in coffee, tea, and other plants, is commonly supplemented in forms like cā€¦
Very Strong
8 trials
Muscle & Recovery
Creatine
Creatine is a natural compound that enhances muscle strength, power, and growth by boosting energy productionā€¦
Very Strong
6 trials
Muscle & Recovery
Whey Concentrate
Whey Protein Concentrate (WPC) is a high-quality protein supplement derived from milk during cheese productionā€¦
Very Strong
5 trials
Cardiovascular
PycnogenolĀ® (French Maritime Pine Bark)
PycnogenolĀ® (Horphag Research) is a standardized extract from the bark of French maritime pine trees grown aloā€¦
Very Strong
4 trials
Energy
Iron
Iron is an essential trace mineral and a central component of hemoglobin, enabling red blood cells to carry oxā€¦
Very Strong
2 trials
Athletic Performance
Sodium / Electrolyte Sodium
Sodium is the primary extracellular cation in the human body ā€” essential for maintaining fluid balance, nerveā€¦
Very Strong
2 trials
Cardiovascular
Potassium
Potassium is the most abundant intracellular cation in the human body, critical for maintaining membrane potenā€¦
Very Strong
1 trial
Cognitive
Alpha-GPC
Alpha-GPC (L-alpha-glycerylphosphorylcholine) is a natural compound and dietary supplement that serves as a prā€¦
Strong
9 trials
Cognitive
Ashwagandha
Ashwagandha is an adaptogenic herb that may reduce stress, enhance mood, and support overall vitality by modulā€¦
Strong
7 trials
Cognitive
KSM-66Ā®
KSM-66 Ashwagandha, a standardized root extract, promotes stress relief and cognitive clarity by balancing corā€¦
Strong
7 trials
Athletic Performance
Beta Alanine
Beta-alanine is a non-essential amino acid found in foods like meat and fish, often used as a supplement to enā€¦
Strong
6 trials
Athletic Performance
L-Citrulline
L-Citrulline is a naturally occurring amino acid that supports nitric oxide production, helping to improve bloā€¦
Strong
5 trials
Weight Management
Capsaicin / Capsicum Extract (CapsimaxĀ®)
Capsaicin is the primary bioactive compound in hot peppers, responsible for their heat and their powerful therā€¦
Strong
3 trials
Muscle & Recovery
Tart Cherry Extract (RestoridynĀ®)
Tart cherry (Montmorency variety) is one of the most clinically validated natural recovery and sleep-support iā€¦
Strong
3 trials
Athletic Performance
Tongkat Ali (LJ100Ā®)
Tongkat Ali (Longjack) is a flowering plant native to Southeast Asia whose root has been used for centuries inā€¦
Strong
3 trials
Cardiovascular
Beetroot
Beetroot is a rich dietary source of inorganic nitrate, which the body converts to nitric oxide ā€” a signalingā€¦
Strong
2 trials
Athletic Performance
L-Carnitine (CarnipureĀ®)
L-Carnitine is a naturally occurring amino acid derivative essential for transporting long-chain fatty acids iā€¦
Strong
2 trials
Muscle & Recovery
L-Leucine
L-Leucine is the most anabolically potent of the three branched-chain amino acids and the primary trigger forā€¦
Strong
2 trials
Athletic Performance
NitrosigineĀ® (Arginine Silicate)
NitrosigineĀ® (Nutrition 21) is a patented, inositol-stabilized arginine silicate complex specifically engineerā€¦
Strong
2 trials
Bone Health
Phosphorus / Phosphate
Phosphorus is the second most abundant mineral in the human body after calcium ā€” comprising approximately 1% oā€¦
Strong
2 trials
Cognitive
Rhodiola Rosea
Rhodiola rosea is an adaptogenic herb from arctic and mountainous regions of Europe and Asia, used for centuriā€¦
Strong
2 trials
Athletic Performance
Sodium Bicarbonate (Baking Soda)
Sodium bicarbonate (baking soda, NaHCOā‚ƒ) is one of the oldest and most studied ergogenic aids in sports sciencā€¦
Strong
2 trials
Metabolic Health
DHEA
Dehydroepiandrosterone (DHEA) is a steroid hormone naturally produced by the adrenal glands, serving as a precā€¦
Moderate
7 trials
Cardiovascular
L-Arginine
L-arginine is an amino acid that serves as a building block for proteins and plays a key role in nitric oxideā€¦
Moderate
7 trials
Cardiovascular
Taurine
Taurine is a sulfur-containing amino acid found in high concentrations in the heart, brain, and muscles, suppoā€¦
Moderate
7 trials
Antioxidant
Astaxanthin
Astaxanthin is a powerful red-orange antioxidant carotenoid best known for its anti-inflammatory and skin-protā€¦
Moderate
5 trials
Muscle & Recovery
Branched-Chain Amino Acids (BCAAs)
Branched-chain amino acids (BCAAs), consisting of leucine, isoleucine, and valine, are popular supplements useā€¦
Moderate
5 trials
Cardiovascular
Pomegranate Extract (PomellaĀ®)
Pomegranate is one of the most antioxidant-dense fruits known, with a polyphenol profile dominated by punicalaā€¦
Moderate
3 trials
Athletic Performance
Betaine / TMG (Trimethylglycine)
Betaine (trimethylglycine, TMG) is a naturally occurring compound found in beets, spinach, and whole grains thā€¦
Moderate
2 trials
Weight Management
CLA (Conjugated Linoleic Acid)
Conjugated linoleic acid (CLA) is a naturally occurring trans fatty acid found predominantly in dairy productsā€¦
Moderate
2 trials
Weight Management
CaloriBurn GPĀ® (Grains of Paradise)
CaloriBurn GPĀ® is NNB Nutrition's premium grains of paradise extract standardized for all three clinically actā€¦
Moderate
2 trials
Athletic Performance
Cordyceps
Cordyceps is a medicinal fungus traditionally used in Tibetan and Chinese medicine for energy, stamina, and loā€¦
Moderate
2 trials
Metabolic Health
Fenugreek
Fenugreek is an annual plant native to the Mediterranean and South Asia, used for millennia in Ayurvedic and tā€¦
Moderate
2 trials
Muscle & Recovery
HMB (Beta-Hydroxy Beta-Methylbutyrate)
Beta-hydroxy beta-methylbutyrate (HMB) is a metabolite of the essential amino acid leucine ā€” produced when leuā€¦
Moderate
2 trials
Athletic Performance
L-Ornithine
L-Ornithine is a non-essential amino acid that plays a central role in the urea cycle ā€” the primary pathway foā€¦
Moderate
2 trials
Weight Management
MetabolaidĀ® (Hibiscus + Lemon Verbena)
MetabolaidĀ® (Monteloeder/SuanNutra) is a patented combination of Hibiscus sabdariffa and Lemon verbena (Lippiaā€¦
Moderate
2 trials
Weight Management
MitoBurnĀ® (L-BAIBA)
MitoBurnĀ® is NNB Nutrition's patented stabilized form of L-Ī²-aminoisobutyric acid (L-BAIBA) ā€” a myokine naturaā€¦
Moderate
2 trials
Muscle & Recovery
Phosphatidic Acid (MediatorĀ®)
Phosphatidic acid (PA) is a phospholipid and the most potent known natural activator of mTORC1 ā€” the master reā€¦
Moderate
2 trials
Energy
RobuvitĀ® (French Oak Wood Extract)
RobuvitĀ® (Horphag Research) is a standardized extract from the heartwood of French oak (Quercus robur) trees gā€¦
Moderate
2 trials
Cognitive
SalidroPureā„¢ (Pure Salidroside)
SalidroPureā„¢ is NNB Nutrition's precision-fermented pure salidroside ā€” the primary bioactive compound in Rhodiā€¦
Moderate
2 trials
Athletic Performance
SenactivĀ®
SenactivĀ® (formerly ActiGinĀ®) is NuLiv Science's patented senolytic sportsceutical ā€” a highly purified blend oā€¦
Moderate
2 trials
Muscle & Recovery
Strengtheraā„¢
Strengtheraā„¢ Muscle Maintenance+Vitality is PLT Health Solutions' botanical blend of Sphaeranthus indicus flowā€¦
Moderate
2 trials
Bone Health
TendoGuardĀ® (Tendon Collagen Complex)
TendoGuardĀ® (Certified Nutraceuticals) is a proprietary blend of collagen peptides specifically fractionated fā€¦
Moderate
2 trials
Cardiovascular
Terminalia Arjuna (OxyjunĀ®)
Terminalia arjuna is a large deciduous tree native to India whose bark has been used in Ayurvedic cardiology fā€¦
Moderate
2 trials
Weight Management
Yohimbe / Yohimbine (Pausinystalia yohimbe)
Yohimbe is the bark of a West African tree containing yohimbine ā€” an alpha-2 adrenergic receptor antagonist wiā€¦
Moderate
2 trials
Metabolic Health
Maca
Maca (Lepidium meyenii), a Peruvian root vegetable from the Andes, is traditionally used to enhance fertility,ā€¦
Limited
8 trials