Top Picks — Athletic Performance

💪 Best Athletic Performance Supplements

Athletic performance supplements ranked by clinical evidence — for strength, endurance, power, and recovery. Creatine, beta-alanine, caffeine, and more.

153 ingredients reviewed Ranked by clinical evidence
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Top 5 — Ranked by Evidence

📈 Fastest Growing Athletic Performance Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

🔬 Future Athletic Performance Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

All Athletic Performance Ingredients (170)

Very Strong
Caffeine
Enhances Alertness and Focus
100–400 mg/day; performance: 3–6 mg/kg body weight 60 minutes pre-exercise; upper safe
Very Strong
Provon® (Whey Protein Isolate — Glanbia)
Muscle Protein Synthesis Stimulation
20-40 g whey protein isolate per serving across published trials. 20 g provides ~2.5 g
Very Strong
Creatine Monohydrate
Strength and high-intensity exercise performance
Standard daily: 3-5 g/day (no loading needed). Optional loading: 20 g/day × 5-7 days,
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Blood pressure — modest effect, mostly in hypertensives
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic
Very Strong
Whey Concentrate
Muscle Growth and Repair
20–40 g post-workout for muscle growth/recovery; 1.6–2 g/kg/day total protein for
Very Strong
AstaZine® (Natural Astaxanthin from Haematococcus pluvialis — BGG)
Visual Function for Digital Screen Users (VDT)
4-12 mg/day AstaZine (research-validated; some applications 12-24 mg)
Very Strong
Creapure® (Pharmaceutical-Grade Creatine Monohydrate)
Strength and power output
Loading: 0.3 g/kg/day for 5–7 days (typically 20 g/day split in 4 doses). Maintenance:
Very Strong
Glucose / Dextrose
Accelerated fluid absorption via SGLT1 cotransport
WHO ORS: 13.5 g glucose/L (75 mmol/L) + 75 mmol/L Na. SPORTS: 4-8% solution (40-80
Very Strong
MegaNatural®-BP (Patented Grape Seed Extract — Polyphenolics)
Blood Pressure Within Normal Range — UC Davis Trials
150-300 mg/day MegaNatural-BP (research-validated)
Very Strong
Potassium
Blood pressure reduction
AI 4,700 mg/day (NAM) or 3,500–4,700 mg/day (WHO/AHA). Supplements limited to 99
Very Strong
Iron
Oxygen transport
18 mg/day (women RDA); 27 mg/day (pregnant); 8 mg/day (men); therapeutic: 150–200 mg
Very Strong
Sodium / Electrolyte Sodium
Fluid balance and hydration maintenance
1,500–2,300 mg/day dietary sodium (AI/UL); electrolyte replacement during exercise:
Strong
Alpha-GPC
Cognitive function in age-related decline
AD/MCI: 400 mg × 3/day = 1200 mg/day. COGNITIVE: 300-600 mg/day. ATHLETIC: 250-600 mg
Strong
Ashwagandha
Testosterone and Muscle
KSM-66® root extract: 300-600 mg/day (most stress/sleep trials). Shoden®: 120-240
Strong
KSM-66®
Stress and Anxiety Reduction
300–600 mg/day KSM-66® root extract (5% withanolides); 300 mg twice daily or 600 mg
Strong
Beta Alanine
Improved Exercise Performance
4–6 grams per day, typically taken for 2–12 weeks
Strong
Quercefit® (Quercetin Phytosome — Indena)
20-Fold Improved Bioavailability vs Standard Quercetin
250-500 mg/day Quercefit® (delivering ~100-200 mg quercetin), one or two tablets
Strong
L-Citrulline
Improved Exercise Performance
3–6 g/day L-citrulline or 6–8 g/day citrulline malate (2:1 ratio) 30–60 minutes
Strong
Phosphatidylserine
Age-related memory complaints — modest benefit
Cognitive (elderly): 100-300 mg/day. Athletic (cortisol): 600-800 mg/day × 10-15 days.
Strong
Pomegranate Extract
Blood pressure and arterial health
Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to
Strong
Creatine HCL
Strength and high-intensity exercise performance
Typical dosing: 1.5-3 g/day of creatine HCL based on marketing claims of higher
Strong
Lactobacillus plantarum 299v (Lp299v / LP299V®)
Boosts non-heme iron absorption from food
PIVOTAL 10¹⁰ CFU/day (10 billion) Axling 2020 athlete 12 wk + Hoekstra 2021 pregnancy
Strong
Soy Protein
Equivalent to whey for muscle and strength gains
MUSCLE/RT: 20-40 g/day. FDA HEART CLAIM: 25 g/day. Anderson 1995 NEJM meta 38 trials:
Strong
Capsaicin / Capsicum Extract (Cayenne Pepper)
Thermogenic energy expenditure (class evidence)
2-10 mg total capsaicinoids per day, typically from 25-100 mg of capsicum extract. 2
Strong
Carnipure® (L-Carnitine — Lonza)
Pharmaceutical-grade manufacturing
Same as generic L-carnitine: 1-3 g/day general supplementation. Specific applications:
Strong
Casein Protein
Sustained amino acid delivery
PRE-SLEEP: 20-40 g casein 30 min before sleep (Res 2012: 40 g intrinsically labeled).
Strong
Dynagenix® (Water-Soluble Boswellia for Joint + Muscle Recovery — PLT Health)
Joint comfort in 5 days (40 mg/day OA trial)
40 mg/day Dynagenix for joint comfort and mobility (the 2025 osteoarthritis trial
Strong
Gynostemma pentaphyllum (Jiaogulan / Southern Ginseng)
Fasting blood glucose and HbA1c reduction
Standardized extract: 200-450 mg twice daily (containing standardized gypenosides).
Strong
LJ100® (Tongkat Ali — HP Ingredients)
Testosterone support trials
Standard formulation use: 100-300 mg LJ100® daily. Most clinical trials use 200
Strong
Milk Protein (MPC/MPI)
Muscle protein synthesis equivalent to whey at matched doses
MPS: 20 g = whey-equivalent. Trommelen 2020: 38 g sustained MPS 5+ hr. PRE-BED: 30-40
Strong
Mitopure® (Urolithin A — Amazentis)
Essentially the only validated commercial urolithin A
Standard clinical dose: 500-1,000 mg/day Mitopure®. Most clinical trials use 500-1,000
Strong
Mycoprotein (Quorn)
LDL cholesterol reduction
Typical dietary serving: 90-180 g cooked mycoprotein per meal (providing 11-22 g
Strong
OPTIZIOME® P3 HYDROLYZER® (Protease Blend for Protein Digestion — BIO-CAT)
14% higher EAA, 15% higher BCAA with whey protein
250 mg per dose providing 31,875 HUT units of proteolytic activity. Typically taken
Strong
Palatinose™ (Isomaltulose)
Low-glycemic carbohydrate energy
25–75 g per dose in acute glycemic and exercise trials, typically replacing sucrose or
Strong
Pea Protein Isolate
Muscle Thickness and Strength Gains
20-50 g per serving; 1.4-2.0 g/kg/day total protein for resistance training. 25 g
Strong
Restoridyn® (Tart Cherry Extract — Anthocyte)
Documented exercise recovery effects
Standard exercise recovery protocol: 480 mg Restoridyn® 1-2 times daily for 4-7 days
Strong
Tart Cherry Extract
Post-exercise muscle recovery and reduced soreness
Exercise recovery: 480 mg standardized extract or 8-12 oz tart cherry juice 1-2 times
Strong
Tongkat Ali
Testosterone support in men with low levels
Standard dose: 100-400 mg/day standardized root extract. Most clinical trials use
Strong
Wellmune (Yeast Beta-Glucan)
Upper Respiratory Tract Comfort
Most Wellmune trials use 250 mg/day, taken daily for periods of 4 to 12 weeks. Some
Strong
Whey Protein Isolate
Supports muscle protein synthesis
20-40 g per serving taken 1-3 times daily, often around resistance training and/or
Strong
AstraGin® (Nutrient Absorption Enhancer)
Amino acid and protein absorption enhancement
25–50 mg/day as absorption enhancer (co-ingredient); 100 mg/day for gut health
Strong
Beetroot
Blood pressure reduction
300–500 mg nitrate/day (equivalent to 70–140 mL concentrated beet juice or 500 mg
Strong
Egg White Albumin Powder
Complete Protein for Muscle Support
20-40 g protein per serving post-exercise or distributed across meals; ~0.3-0.4 g
Strong
GeniusPure® (High-Purity Alpha-GPC)
Memory, learning, and cognitive enhancement
300–600 mg/day alpha-GPC (as standard 50% — adjust for GeniusPure® 70% or 90%
Strong
HydroCurc® (Highly Bioavailable Curcumin)
Enhanced Bioavailability vs Standard Curcumin
500 mg/day; clinical trials use 250-1,000 mg/day depending on indication
Strong
L-Carnitine
Cardiovascular support in heart failure and angina
General supplementation: 1-3 g/day L-carnitine. Athletic recovery: 2 g/day L-carnitine
Strong
L-Leucine
Muscle protein synthesis activation
2–5 g/dose with protein; MPS threshold: ~2–3 g leucine per meal; BCAA supplements:
Strong
NUTRALYS® Pea Protein (Roquette)
Complete Plant Protein Profile
20-50 g/day pea protein for muscle/sports applications; per product specification for
Strong
Nitrosigine® (Arginine Silicate)
Superior nitric oxide and arginine elevation
1,500 mg/day; most studies use 1,500 mg taken 30–60 minutes pre-exercise
Strong
PEAK ATP® (Disodium Adenosine Triphosphate)
Strength and lean body mass gains
400 mg/day PEAK ATP® (disodium ATP); acute: 400 mg taken 30–60 minutes pre-exercise;
Strong
PepForm® (Leucine-Rich Whey Peptides — Glanbia Nutritionals)
Increased muscle protein synthesis in older adults
Per published trial protocols: 15 g leucine-enriched whey beverage delivering 4.2 g
Strong
PeptiStrong® (AI-Discovered Fava Bean Peptides)
Muscle protein synthesis and recovery acceleration
2,400 mg/day PeptiStrong® (clinical dose across 3 RCTs); taken daily; muscle recovery
Strong
Phosphorus / Phosphate
Bone mineral density and skeletal strength
700 mg/day (RDA for adults); athletic phosphate loading: 3–4 g/day sodium phosphate
Strong
Rhodiola Rosea
Stress and fatigue reduction
200–600 mg/day standardized extract; taken before meals
Strong
RipFACTOR® (Botanical Muscle Accelerator)
Strength gains within 14 days — clinically proven
Performance dose: 325 mg/day (significant strength and endurance benefits);
Strong
Sensoril® (Ashwagandha Extract — Verdure/Natreon)
Stress Reduction
125-500 mg/day Sensoril (research-validated; stress applications often 250 mg/day)
Strong
Sodium Bicarbonate (Baking Soda)
High-intensity exercise performance enhancement
0.3 g/kg body weight (typically 20–25 g for 70 kg person) taken 60–90 minutes before
Strong
TestFACTOR® (Testosterone + Sexual Wellness)
Total and free testosterone increase across 4 RCTs
PERFORMANCE: 325 mg/day × 8 wk testosterone + sexual function. ULTRA-PERFORMANCE: 650
Strong
Testofen® (Fenugreek for Male Vitality)
Free Testosterone Increase
300-600 mg/day (libido lower; resistance training higher)
Strong
Urolithin A
Mitophagy induction (distinguishing mechanism)
Standard dose: 500-1,000 mg/day urolithin A direct supplementation. Most clinical
Strong
Velositol® (Chromium-Driven MPS Complex - Nutrition 21)
Doubles Muscle Protein Synthesis (MPS)
2 g/day Velositol with protein (research-validated)
Strong
Zynamite® PX (Mango Leaf Extract for Sports Performance)
Peak power output improvement in single dose
140 mg Zynamite® + 140 mg quercetin (single dose, 1 hour pre-exercise); 140 mg/day +
Strong
Amino9® (Clinically Validated EAA Blend)
Complete muscle protein synthesis stimulation
5.6g Amino9® per serving (clinical dose used in published RCT); typically 5–10g/day;
Strong
DL-185® (Dileucine)
Superior muscle protein synthesis vs. leucine
2,000 mg (2g) once daily; absorbed 185% faster than equivalent leucine dose; clinical
Strong
PeakO2® (Adaptogenic Mushroom Blend)
VO2 max improvement and oxygen utilization
1–4g/day for ongoing use; 4g/day for clinical performance benefits (21-day loading);
Strong
goCOCOA® (Cocoa Flavanol Extract)
Cardiovascular health and blood pressure reduction
200–400 mg/day cocoa flavanols (epicatechin equivalent); cardiovascular/cognitive:
Moderate
L-Arginine
Improved Blood Flow
3–6 g/day for cardiovascular effects; 6–10 g/day pre-exercise for blood flow; often
Moderate
Taurine
Heart Health
500–3,000 mg/day; energy drinks typically contain 1,000 mg; athletic performance: 1–3
Moderate
Astaxanthin
Eye health and visual function
4–12 mg/day from Haematococcus pluvialis extract; skin: 4–6 mg/day; exercise recovery:
Moderate
Branched-Chain Amino Acids (BCAAs)
Muscle Growth and Recovery
5–10 g/day (2:1:1 leucine:isoleucine:valine ratio); pre/intra/post-workout; leucine
Moderate
Bovine Colostrum
Exercise-induced gut permeability — strongest evidence
Athletic gut/immune: 20-60 g/day × 4-12 weeks. Pediatric diarrhea: 7-14 g/day. Choose
Moderate
PrimaVie® (Shilajit Extract — Natreon)
Testosterone support in middle-aged men (foundational trial)
Clinical trial dose: 250 mg twice daily (500 mg/day total) for 90 days. CoQ10
Moderate
Shilajit
Testosterone increase in middle-aged men
Standard clinical dose: 250 mg twice daily (500 mg/day total) of purified shilajit
Moderate
Adenosine 5'-Triphosphate (ATP)
Athletic Performance Adjunct
400 mg/day disodium ATP (research-validated dose, primarily based on PEAK ATP studies)
Moderate
Beef Protein Isolate
Lean mass and strength gains comparable to whey (mixed evidence)
MUSCLE/HYPERTROPHY: 20-46 g daily (Sharp 2018: 46 g; standard 20-30 g/dose
Moderate
Betalains (Beetroot Pigments)
Athletic performance enhancement (beetroot RCTs)
BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains).
Moderate
Black Ginger (Kaempferia parviflora / Krachaidum / Thai Ginseng)
Exercise capacity and physical performance
Standard dose: 100-180 mg/day standardized extract (typically 5-7% methoxyflavones).
Moderate
Capsinoids (Non-Pungent Capsaicin Analogs)
Increased energy expenditure and fat oxidation
WEIGHT MANAGEMENT (Snitker 2009 + Galgani 2010): 6 mg capsinoids daily × 4-12 wk.
Moderate
Cluster Dextrin® (Highly Branched Cyclic Dextrin)
Faster gastric emptying than maltodextrin
15–70 g pre- or intra-workout (typical: 30–50 g mixed in 500 mL fluid). Endurance
Moderate
Cococin® (Freeze-Dried Coconut Water — Sabinsa)
Hair fall reduction — 81% (dermatologist assessment)
Variable by application. Hair/skin serum: multi-patented composition with Saberry® and
Moderate
Coconut Water
Natural electrolyte rehydration
HYDRATION: 240-500 mL (8-17 oz) general. POST-EX REHYDRATION (~2% body mass loss):
Moderate
Eurycomanone (Tongkat Ali Quassinoid)
Testosterone support in men with low levels
Physta® 200-400 mg/day; LJ100® 100-200 mg/day; purified eurycomanone 50-200 mg/day.
Moderate
FORTIGEL® Bioactive Collagen Peptides
Supports activity-related knee comfort
5 g per day of FORTIGEL® dissolved in water or beverage, typically taken once daily
Moderate
HydroMax®
Pre-exercise hyperhydration
Pre-exercise glycerol hyperhydration: typically 1.0–1.5 g glycerol per kg body weight
Moderate
Insect Protein (Cricket / Mealworm)
Muscle protein synthesis equivalent to milk protein
MUSCLE PROTEIN SYNTHESIS: 30 g lesser mealworm = MPS equivalent to 30 g milk protein.
Moderate
Lacprodan® (Branded Family of Hydrolyzed Whey and Milk Proteins)
Supports muscle protein synthesis
Class-level whey protein dosing in muscle protein synthesis trials is typically 20–40
Moderate
Molecular Hydrogen (H2)
Metabolic syndrome improvement (pivotal)
HRW: 1.5-7 ppm H2 in water, 0.5-2 L/day. LeBaron 2020 high-conc: ~7 ppm × 24 wk
Moderate
MuscleGuard™ (Vegan 4-Nutrient Sports Performance Blend — Lonza)
63% increase in composite muscle score (no exercise)
Single daily dose providing the patent-pending ratio: 1500 mg L-Carnitine + 2000 mg
Moderate
MyoVera™ (Chromium-Based Muscle Protein Synthesis Amplifier — Nutrition 21)
Amplified muscle protein synthesis response
MyoVera daily dose per Nutrition21 specifications — to be taken alongside protein
Moderate
Oceanix™ (Marine Phytoplankton Recovery Booster — Lonza)
Explosive strength preservation (98% vs 68% baseline)
25 mg/day Oceanix — the small concentrated clinical dose used across multiple trials.
Moderate
Paraxanthine
Acute Cognitive Performance
50-200 mg as a single acute dose; 100-200 mg is the most commonly studied range for
Moderate
Sustamine® (L-Alanyl-L-Glutamine)
Enhanced Hydration and Fluid Absorption
Exercise/hydration trials used roughly 1–2 g per 500 mL of fluid during activity, or
Moderate
Whey Protein Hydrolysate
Supports rapid post-exercise recovery
20-30 g of whey protein hydrolysate per serving, taken before, during, or shortly
Moderate
cellflo6® (Gallate-Enhanced Green Tea Procyanidins — PLT Health)
Enhanced blood flow following resistance exercise
600 mg/day cellflo6 — the dose showing significant blood flow improvements in the
Moderate
zümXR® (Targeted-Release Caffeine Technology — PLT Health)
Sustained energy without spike or crash
Caffeine doses typically 50-300 mg per serving (matching immediate-release caffeine
Moderate
Betaine / TMG (Trimethylglycine)
Athletic performance — power and strength
2–6 g/day; athletic performance: 2.5 g/day (most studied dose); homocysteine
Moderate
Citrulline Malate
Resistance Training Performance
6-8 g pre-exercise (most clinical research dose); 8 g taken 60 minutes before training
Moderate
Cordyceps
Exercise performance and endurance
1,000–3,000 mg/day mycelium powder; 400–800 mg/day standardized extract
Moderate
ElevATP®
Supports Endogenous ATP Production
150 mg/day in branded human studies, taken with or without other workout ingredients.
Moderate
HMB (Beta-Hydroxy Beta-Methylbutyrate)
Muscle mass preservation during inactivity and aging
3 g/day in divided doses (1 g three times daily); HMB-FA: 1–3 g/day pre-workout;
Moderate
L-Ornithine
Exercise fatigue reduction via ammonia clearance
2–6 g/day; fatigue reduction: 2 g before exercise; sleep: 400 mg before bedtime; liver
Moderate
Metabolaid® (Hibiscus + Lemon Verbena)
AMPK activation and fat oxidation
500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before exercise
Moderate
MitoBurn® (L-BAIBA)
White-to-brown fat conversion
250–500 mg/day; 500 mg is the full clinical dose
Moderate
Phosphatidic Acid (Mediator®)
Muscle hypertrophy and lean mass gains
750 mg/day; timing: taken around resistance training sessions; 8-week minimum for
Moderate
Robuvit® (French Oak Wood Extract)
Chronic fatigue reduction
300 mg/day Robuvit®; fatigue studies use 300 mg/day; athletic performance: 300 mg/day
Moderate
SalidroPure™ (Pure Salidroside)
Anti-fatigue and endurance
3–5 mg/day pure salidroside (equivalent to ~500 mg 1% standardized Rhodiola extract)
Moderate
Senactiv®
VO2 max and endurance improvement
50–100 mg/day; 50 mg is the established clinical dose
Moderate
Sodium Citrate
Extracellular Buffering Support
Ergogenic protocols use 0.3-0.5 g/kg body mass (about 0.5 g/kg most effective), taken
Moderate
Strengthera™
Lower body strength improvement
650 mg/day; significant results beginning at 4 weeks
Moderate
TendoGuard® (Tendon Collagen Complex)
Tendon and ligament structural support
5–10 g/day collagen peptide complex; most tendon studies use 5–10 g/day type I
Moderate
Terminalia Arjuna (Oxyjun®)
Cardiorespiratory endurance improvement
500 mg/day Oxyjun®; traditional cardiac use: 1–3 g/day bark powder; effects on
Moderate
Yohimbe / Yohimbine (Pausinystalia yohimbe)
Fat loss — particularly stubborn adipose
5–20 mg/day yohimbine HCl; fat loss: 20 mg/day (split doses) in clinical studies;
Moderate
ZMA® (Zinc Magnesium Aspartate — Lonza)
Athletic Recovery and Muscle Strength
30 mg zinc + 450 mg magnesium + 10.5 mg B6 (per ZMA standard formulation)
Moderate
Carb10® (Pea Starch Carbohydrate)
82% less insulin response than maltodextrin
15–25g per serving for workout fueling; can be used pre, intra, or post-workout;
Moderate
Ecdysterone / Turkesterone (Ecdysteroid Anabolics)
Lean muscle mass increase without hormonal side effects
Ecdysterone: 500–1,000 mg/day (12-week RCTs); Turkesterone: 500 mg/day; both: taken
Moderate
Epicatechin (Myostatin Inhibitor / Muscle Flavonol)
Myostatin inhibition and follistatin elevation
50–200 mg/day (-)-epicatechin; muscle/anabolic applications: 150–200 mg/day;
Moderate
Gremin™ (Green Coffee + Curcumin BioFusion Complex)
Muscle recovery and DOMS reduction
Per Gremin™ clinical dosing; BioFusion Technology formulation per manufacturer
Moderate
HydroPrime® (Stabilized Glycerol)
Hyperhydration and plasma volume expansion
2–6g glycerol (as HydroPrime®) 1–2× daily; pre-exercise hyperhydration: 1g/kg
Moderate
MalTor™ (Taurine + L-Malic Acid Recovery Complex)
Exercise recovery acceleration
Per MalTor™ clinical specifications; NutriScience Innovations product data; 5g MalTor™
Moderate
NUTRALYS® Fava Bean Protein (Roquette)
Pulse Family Diversification
Per Roquette NUTRALYS Fava product specification; typical 20-30 g/day for protein
Moderate
NUTRALYS® Wheat Protein (Roquette)
Complementary to Legume Proteins
Per Roquette NUTRALYS Wheat / VITEN product specification
Moderate
Nitratene® (Stabilized Beet Root Nitrate)
Nitric oxide production and vasodilation
200–400 mg inorganic nitrate equivalent; 1–3 hours pre-exercise for peak NO elevation;
Moderate
Oxystorm® (Red Spinach Nitrate)
Superior nitrate density — 9× more than beetroot
1–2g Oxystorm® providing ~200–400 mg dietary nitrate; consume 2–3 hours before
Limited
Maca
Improved Sexual Function and Libido
1.5–3 g/day dried root powder; gelatinized maca preferred for digestion; 8–12 weeks
Limited
Agmatine
Neuropathic Pain Reduction
PAIN TRIALS: 1.335-3.560 g/day. RCT: 2.670 g/day divided × 14 d. BODYBUILDING: 500
Limited
Pyruvate (Calcium Pyruvate / Sodium Pyruvate)
Modest body weight reduction
MODERN: 5-10 g/day Ca/Na pyruvate (Kalman 1999: 6 g/day × 6 wk). STANKO 1990s: 22-53
Limited
4-Hydroxy-L-Isoleucine
Glucose-dependent insulin secretion support
Standalone 4-OH-Ile human data is limited; preclinical doses range 18–50 mg/kg in
Limited
Arnica (Arnica montana)
Topical arnica gel for bruising — modest effect
TOPICAL (recommended): 20% tincture or 10-25% gel 2-4×/day. OTC: Arnicare®, Traumeel®.
Limited
Aspartic Acid / D-Aspartic Acid (DAA)
Testosterone Support (Mixed Evidence)
DAA: 2,500–3,000 mg/day in clinical trials; supplemental cycles typically 12 days to 4
Limited
Beef Heart (Desiccated)
Richest natural food source of CoQ10
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef
Limited
Bemethyl (Bemitil / Metaprot)
Asthenic disorders (1988 RCT vs piracetam/pyriditol)
RUSSIAN/CIS APPROVED: 250-500 mg 1-2×/day for asthenia; courses 3-5 days with 2-3 day
Limited
Mildronate (Meldonium)
Post-myocardial infarction heart failure
RUSSIAN/LATVIAN APPROVED: 500-1,000 mg/day oral. POST-MI: 1,000 mg/day IV × 10-14
Limited
Silk Amino Acids / Silk Fibroin Hydrolysate
Cognitive function support — memory, attention, mental focus
COGNITIVE: 200-600 mg silk fibroin enzyme hydrolysate (FEH)/day × 3-16 wk. STAMINA:
Limited
Ursolic Acid
Single small positive RT trial (n=16) showed strength benefit
MUSCLE/STRENGTH: 400-450 mg/day divided (Bang 2014: 450 mg POSITIVE; Pereira 2020: 400
Limited
Bee Pollen
Nutrient-dense whole food
Traditional intake ranges from 1 teaspoon (about 5 g) to 1 tablespoon (15 g) daily;
Limited
CordyFuel™ (Branded Cordyceps Extract)
Supports exercise endurance and oxygen utilization
Branded-specific dosing is not well defined in indexed trials. Class-level cordyceps
Limited
CordycepsPrime™ (Branded Cordyceps Extract)
Exercise tolerance and aerobic capacity support
CordycepsPrime™ label dose per manufacturer; broader cordyceps literature has used 1–4
Limited
Creatinol-O-Phosphate (COP)
Cardioprotective and anti-ischemic mechanism (historical cardiology)
Italian cardiology trials used variable parenteral and oral doses depending on
Limited
GlycerPump™
Pre-exercise hyperhydration (glycerol class)
No branded GlycerPump™ RCTs. Glycerol-class hyperhydration protocols typically use
Limited
GlycerSize™
Pre-exercise hyperhydration (glycerol class)
No branded GlycerSize™ RCTs. Glycerol-class hyperhydration protocols typically use
Limited
Kre-Alkalyn
Provides Creatine for Energy Systems
Manufacturer-recommended use is 1.5-3 g/day without a loading phase; head-to-head
Limited
L-Histidine
Carnosine Precursor
4 g/day for atopic dermatitis trials; 1.5–4 g/day in carnosine precursor research;
Limited
L-Isoleucine
Muscle Protein Synthesis (Adjunct to Leucine)
Typically as part of BCAA blends (2:1:1 leucine:isoleucine:valine); standalone rarely
Limited
L-Valine
Muscle Protein Synthesis (Adjunct)
Typically as part of BCAA blends (2:1:1 leucine:isoleucine:valine); standalone rarely
Limited
Magnesium Aspartate
Soluble, absorbable form
Repletion typically targets 200-400 mg elemental magnesium daily; older fatigue
Limited
PureATP (Pure Adenosine 5'-Triphosphate Disodium)
Athletic Performance (Extrapolated Evidence)
400 mg/day disodium ATP (extrapolated from PEAK ATP research; PureATP-specific studies
Limited
Sodium Phosphate
Proposed Oxygen Delivery Support
Loading protocols typically use about 1 g of sodium phosphate four times daily
Limited
GBB (Gamma-Butyrobetaine / 'Super Carnitine')
Endogenous L-carnitine elevation
10–25 mg/day GBB-EE (ethyl ester) as thermogenic/carnitine elevator; very low dose
Limited
Stadice® (Joint Health Complex)
Joint comfort and mobility support
Per Stadice® product specifications; clinical dosing per Zeus Hygia product
Limited
Testncrease® (Testosterone Support Blend)
Healthy testosterone level support
Per Testncrease® product specifications; typically 2 capsules/day with meals; clinical
Preliminary
Glucuronolactone (D-Glucurono-γ-Lactone)
Component of energy drink combinations
RED BULL: 600 mg per 250 mL serving. EU SCF safe up to 250 mg/kg/day (2003). ISOLATED
Preliminary
Velvet Antler (Deer/Elk)
Single small trial: knee extensor strength (with caveats)
ATHLETIC: 1.5-1.6 g/day or 560 mg/day. TCM TRADITIONAL: 0.3-1 g/day powdered.
Preliminary
Laxogenin (5-Alpha-Hydroxy Laxogenin Plant Steroid)
Non-hormonal muscle protein synthesis support
50–100 mg/day laxogenin; limited human clinical data available; animal and cell
Strong
AlphaSize® (Alpha-GPC — Chemi Nutra)
Memory and cognition
300 to 600 mg per day for cognition; about 600 mg pre-exercise in sports studies.
Strong
AstaPure® (Natural Astaxanthin — Algatech)
Antioxidant and recovery support
4 to 12 mg per day, taken with a fat-containing meal for absorption.
Strong
BetaTor® (HMB Free Acid)
Muscle preservation
About 1 to 3 grams per day, often around training.
Moderate
BODYBALANCE® (Bioactive Collagen Peptides — Gelita)
Body composition with exercise
About 15 grams per day, combined with resistance training.
Moderate
CherryPure® (Montmorency Tart Cherry — Shoreline Fruit)
Exercise recovery
Often 480 mg of cherry powder per day, or the equivalent in juice concentrate.
Moderate
Recoverben® (Lemon Verbena Extract — Monteloeder)
Muscle recovery
Around 400 mg per day, often taken before exercise.
Limited
Vinitrox™ (Grape and Apple Polyphenols — Nexira)
Nitric oxide and blood flow
Around 500 mg per day, often taken before exercise.
Moderate
CarnoLife® (L-Carnitine L-Tartrate)
Exercise recovery
Commonly 1 to 2 grams of L-carnitine L-tartrate per day.
Limited
Prodiet® Colostrum (Bovine Colostrum — Ingredia)
Immune support
Commonly a few grams of colostrum per day.
Strong
NewCaff™ (Microencapsulated Natural Caffeine)
Energy and alertness
Commonly 100 to 200 mg per serving; performance studies use about 3 to 6 mg per kg.
Strong
PurCaf® (Organic Caffeine from Green Coffee)
Energy and alertness
Commonly 100 to 200 mg per serving; performance studies use about 3 to 6 mg per kg.
Strong
InnovaTea® (Natural Caffeine from Tea — NutriScience)
Energy and alertness
Commonly 100 to 200 mg of caffeine per serving.
Limited
AminoZorb® (Buffered Branched-Chain Amino Acids)
Muscle support
Commonly 5 to 10 grams of BCAAs per day.
Limited
FitNox® (Plant Nitric Oxide Complex)
Nitric oxide and blood flow
Around 250 mg per day.
Moderate
PurTea® (Organic Green Tea Caffeine — Applied Food Sciences)
Energy and alertness
Commonly 100 to 200 mg of caffeine per serving.
Limited
Kinetiq® (Bitter Orange Extract — Novel Ingredients)
Thermogenesis and weight management
Commonly providing around 50 mg of p-synephrine per day.
Strong
Carbelac® (Whey Protein Concentrate — Carbery)
Muscle building and strength
Commonly 20 to 40 g of whey protein per serving.