Home Ingredients NatAxtin™ (Chilean Astaxanthin — Stratum Nutrition)
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NatAxtin™ (Chilean Astaxanthin — Stratum Nutrition)

Haematococcus pluvialis
Evidence Level
Strong
2 Clinical Trials
6 Documented Benefits
4/5 Evidence Score

NatAxtin™ is a chilean-sourced astaxanthin ingredient distributed by Stratum Nutrition — distinguished by Chilean Haematococcus pluvialis cultivation. Astaxanthin is one of the most powerful natural antioxidants (~6000× more potent than vitamin C in some assays). Used for: antioxidant supplementation, skin health, eye health, cardiovascular markers, exercise recovery.

Studied Dose 4-12 mg/day astaxanthin (typical supplemental range)
Active Compound Astaxanthin from Haematococcus pluvialis (Chilean source)

Benefits

Powerful Antioxidant Activity

Astaxanthin among the most powerful natural antioxidants — singlet oxygen quenching activity ~6000× vitamin C in some assays; lipid-soluble enabling cell membrane protection.

Supported by Trial 1, Trial 2

Skin Health and UV Protection

Astaxanthin reduces UV-induced skin damage; supports skin elasticity, hydration, fine line reduction.

Supported by Trial 1

Eye Health and Visual Function

Crosses blood-retinal barrier; protects retinal photoreceptors from oxidative damage; complementary to lutein/zeaxanthin.

Exercise Recovery

Reduces exercise-induced oxidative stress and inflammation markers; supports recovery.

Supported by Trial 2

Cardiovascular Markers

Modest effects on blood lipid profile, oxidized LDL, blood pressure markers.

Supported by Trial 2

Chilean Source Heritage

Chile produces high-quality H. pluvialis astaxanthin; established cultivation expertise.

Supported by Trial 1, Trial 2

Mechanism of action

1

Singlet Oxygen Quenching

Among most efficient singlet oxygen quenchers known; multiple conjugated double bonds dissipate reactive oxygen species.

2

Membrane Antioxidant

Astaxanthin's molecular structure enables it to span cellular membranes — protects both inside and outside cell membrane simultaneously.

3

Crosses Blood-Brain and Blood-Retinal Barriers

Unique among carotenoids in crossing both BBB and BRB — relevant to brain and eye applications.

4

Anti-Inflammatory NF-kB Modulation

Modulates NF-kB inflammatory pathway.

Clinical trials

1
Astaxanthin for Skin Health — Multiple Trials
PubMed

Multiple astaxanthin trials on skin elasticity, hydration, UV protection.

Adults across studies.

Skin appearance and quality improvements; UV protection effects.

2
Astaxanthin for Cardiovascular and Exercise Recovery
PubMed

Multiple astaxanthin trials on cardiovascular markers and exercise applications.

Various populations.

Modest cardiovascular effects; exercise recovery improvements.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress (rare).
Pinkish-red skin coloration possible at very high doses (carotenodermia, harmless, reversible).
Allergic reactions rare.

Important Drug interactions

Anticoagulants — astaxanthin has modest antiplatelet effects.
Antihypertensives — modest BP effects.
5-alpha reductase inhibitors — theoretical interaction.
Pregnancy — limited specific safety data; consult.
Lactation — limited data.
Pre-surgery — discontinue 1-2 weeks for bleeding considerations.

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Frequently asked questions about NatAxtin™ (Chilean Astaxanthin — Stratum Nutrition)

What is NatAxtin?

NatAxtin™ is a chilean-sourced astaxanthin ingredient distributed by Stratum Nutrition — distinguished by Chilean Haematococcus pluvialis cultivation. Astaxanthin is one of the most powerful natural antioxidants (~6000× more potent than vitamin C in some assays).

What is NatAxtin used for?

NatAxtin is researched primarily for Antioxidant, Hair, Skin & Nails, and Eye Health. Astaxanthin among the most powerful natural antioxidants — singlet oxygen quenching activity ~6000× vitamin C in some assays; lipid-soluble enabling cell membrane protection.

What is the recommended dosage of NatAxtin?

The clinically studied dose is 4-12 mg/day astaxanthin (typical supplemental range) Always follow the product label and check with a healthcare provider for personal advice.

Is NatAxtin safe, and does it have side effects?

For most healthy adults, NatAxtin is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild GI distress (rare). It may also interact with some medications. NatAxtin is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does NatAxtin interact with any medications?

Possible interactions include: Anticoagulants — astaxanthin has modest antiplatelet effects. Antihypertensives — modest BP effects. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for NatAxtin?

NutraSmarts rates the evidence for NatAxtin as Strong (4 out of 5). It is backed by 2 clinical trials and 4 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(4 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi Y Protective effects of astaxanthin on skin deterioration J Clin Biochem Nutr. 2017;61(1):33-39. doi: 10.3164/jcbn.17-35.PubMedUsed to support: Supports the skin claim: oral Haematococcus pluvialis astaxanthin helped maintain skin moisture/condition and mitigated UV-associated deterioration. Honesty: small industry-funded trial focused on skin biomarkers; generic astaxanthin, not NatAxtin-specific.
  2. Res PT, Cermak NM, Stinkens R, Tollakson TJ, Haenen GR, Bast A, et al. Astaxanthin supplementation does not augment fat use or improve endurance performance Med Sci Sports Exerc. 2013;45(6):1158-65. doi: 10.1249/MSS.0b013e31827fddc4.PubMedUsed to support: Honest counterpoint to the exercise/recovery claim: a double-blind RCT in trained cyclists found astaxanthin did not increase fat oxidation or improve endurance performance. Honesty: a clean null result that tempers astaxanthin sports-performance marketing; generic astaxanthin, not NatAxtin-specific.
  3. Brown DR, Warner AR, Deb SK, Gough LA, Sparks SA, McNaughton LR The effect of astaxanthin supplementation on performance and fat oxidation during a 40 km cycling time trial J Sci Med Sport. 2021;24(1):92-97. doi: 10.1016/j.jsams.2020.06.017.PubMedUsed to support: Supports the exercise/fat-oxidation claim with honest limits: a crossover trial of astaxanthin during a 40 km cycling time trial found effects on performance/fat oxidation were modest at best. Honesty: small crossover study, generic astaxanthin; consistent with the overall mixed astaxanthin exercise literature.
  4. Djordjevic B, Baralic I, Kotur-Stevuljevic J, Stefanovic A, Ivanisevic J, Radivojevic N, Andjelkovic M, Dikic N Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players J Sports Med Phys Fitness. 2012;52(4):382-92..PubMedUsed to support: Supports the exercise/recovery and antioxidant claims: astaxanthin (4 mg/day for 90 days) attenuated some muscle-damage and oxidative-stress markers in elite young athletes versus placebo. Honesty: small RCT, effects were on biomarkers and partially inconsistent; generic astaxanthin.