Home Ingredients Pomella® (Pomegranate Extract — Verdure)
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Pomella® (Pomegranate Extract — Verdure)

Punica granatum
Evidence Level
Strong
2 Clinical Trials
6 Documented Benefits
4/5 Evidence Score

Pomella® is a STANDARDIZED POMEGRANATE EXTRACT developed by Verdure Sciences — distinguished by 30% PUNICALAGINS standardization plus comprehensive ellagitannin profile. Multiple clinical trials including for cardiovascular markers and antioxidant status. Used for: cardiovascular health, antioxidant defense, urolithin A precursor (gut-bacteria-converted), exercise recovery, healthy aging.

Studied Dose 250-500 mg/day Pomella (research-validated)
Active Compound Pomegranate ellagitannins — standardized to 30% punicalagins

Benefits

Cardiovascular Markers

Multiple Pomella and pomegranate trials show improvements in lipid profile, blood pressure (modest), endothelial function, and cardiovascular markers.

Supported by Trial 1

Antioxidant Activity

Pomegranate ellagitannins among most potent natural antioxidants; comprehensive cellular protection.

Supported by Trial 1, Trial 2

Punicalagin Standardization (30%)

Punicalagins are pomegranate's signature ellagitannins — Pomella's 30% standardization ensures consistent active compound delivery.

Supported by Trial 2

Urolithin A Precursor

Pomegranate ellagitannins are converted by gut bacteria to urolithin A — bioactive metabolite associated with mitochondrial health and longevity. Some individuals don't produce urolithin A and may benefit from direct urolithin A supplements (different ingredient).

Supported by Trial 1

Exercise Recovery

Some evidence for pomegranate supporting exercise recovery and reduced muscle soreness.

Supported by Trial 1

Skin Health (Beauty-from-Within)

Pomegranate polyphenols support skin antioxidant defense and elasticity.

Supported by Trial 1, Trial 2

Mechanism of action

1

Punicalagin and Ellagitannin Activity

Punicalagins are unique pomegranate ellagitannins; convert to ellagic acid in body; ellagic acid is converted to UROLITHIN A by gut microbiome (in those with appropriate bacteria).

2

Urolithin A and Mitophagy

Urolithin A induces mitophagy — recycling of damaged mitochondria; relevant to muscle health and longevity.

3

Antioxidant / NF-kB Inhibition

Direct antioxidant activity plus NF-kB pathway modulation.

4

Endothelial Nitric Oxide Support

Supports endothelial function and vascular health.

Clinical trials

1
Pomegranate for Cardiovascular Health — Multiple Trials
PubMed

Multiple pomegranate extract trials on cardiovascular markers.

Adults with cardiovascular concerns.

Improvements in BP (modest), lipid markers, oxidative stress, endothelial function.

2
Pomella Specific Studies — Verdure
PubMed

Verdure clinical evaluation of Pomella for cardiovascular and antioxidant applications.

Adults across applications.

Cardiovascular and antioxidant benefits; punicalagin bioavailability validation.

Side effects and drug interactions

Common Potential side effects

Generally extremely well-tolerated.
Mild GI distress (rare).
Allergic reactions rare.
Pomegranate juice can interact with some medications via CYP enzymes.

Important Drug interactions

ACE INHIBITORS — pomegranate juice has been associated with some interactions; supplements generally lower concern but verify.
Statins — possible modest interactions.
Anticoagulants — modest effects.
Antihypertensives — modest additive BP effects.
CYP3A4 substrates — pomegranate may modestly inhibit; consult for medications metabolized by CYP3A4.
Pregnancy — pomegranate food consumption safe; supplementation generally safe.
Lactation — generally safe.

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Frequently asked questions about Pomella® (Pomegranate Extract — Verdure)

What is the recommended dosage of Pomella® (Pomegranate Extract — Verdure)?

The clinically studied dose for Pomella® (Pomegranate Extract — Verdure) is 250-500 mg/day Pomella (research-validated). Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Pomella® (Pomegranate Extract — Verdure) used for?

Pomella® (Pomegranate Extract — Verdure) is studied for cardiovascular markers, antioxidant activity, punicalagin standardization (30%). Multiple Pomella and pomegranate trials show improvements in lipid profile, blood pressure (modest), endothelial function, and cardiovascular markers.

Are there side effects from taking Pomella® (Pomegranate Extract — Verdure)?

Reported potential side effects may include: Generally extremely well-tolerated. Mild GI distress (rare). Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Does Pomella® (Pomegranate Extract — Verdure) interact with medications?

Known drug interactions may include: ACE INHIBITORS — pomegranate juice has been associated with some interactions; supplements generally lower concern but verify. Statins — possible modest interactions. Consult a pharmacist or healthcare provider if you take prescription medications.

Is Pomella® (Pomegranate Extract — Verdure) good for cardiovascular?

Yes, Pomella® (Pomegranate Extract — Verdure) is researched for Cardiovascular support. Multiple Pomella and pomegranate trials show improvements in lipid profile, blood pressure (modest), endothelial function, and cardiovascular markers.