Home Ingredients SelectSIEVE® Rainbow (Black Rice & Citrus Polyphenol Complex — Roelmi HPC)
Hair, Skin & NailsAntioxidant

SelectSIEVE® Rainbow (Black Rice & Citrus Polyphenol Complex — Roelmi HPC)

Oryza sativa
Evidence Level
Limited
2 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

SelectSIEVE® Rainbow is an oral beauty-from-within complex from Roelmi HPC that combines anthocyanins from black rice, flavonoids from citrus, and fibers and proteolytic enzymes from kiwi and pineapple. It is positioned to support skin tone, elasticity, and healthy microcirculation. The evidence comes from the activity of its individual plant components rather than from published trials of the finished blend, so it is best viewed as preliminary.

Studied Dose 300 mg per day.
Active Compound Black rice (Oryza sativa) anthocyanins, citrus flavonoids, and kiwi and pineapple fibers with proteolytic enzymes (bromelain).

Benefits

Beauty-from-within skin support

The anthocyanins and polyphenols in the blend act as antioxidants that help support skin tone and elasticity from the inside.

Supported by Trial 2

Microcirculation support

Citrus flavonoids have been studied for supporting healthy microcirculation and venous tone in the legs.

Supported by Trial 1

Antioxidant defense

Black rice anthocyanins and citrus flavonoids provide antioxidant activity that helps protect skin and tissues from oxidative stress.

Supported by Trial 2, Trial 1

Mechanism of action

1

Antioxidant polyphenols

Anthocyanins from black rice and flavonoids from citrus scavenge free radicals and support the skin's antioxidant defenses.

2

Microcirculatory support

Citrus flavonoids are studied for supporting capillary integrity and venous tone, which underlies the blend's draining and microcirculation positioning.

3

Proteolytic enzymes

Bromelain from pineapple is a proteolytic enzyme studied for supporting a normal inflammatory response and tissue comfort.

Clinical trials

1
Citrus Flavonoids and Venous Microcirculation — Evidence Review
PubMed

Review of citrus flavonoid fractions (diosmin / micronized purified flavonoid fraction) for chronic venous disorders. This is evidence for the citrus component, not a trial of SelectSIEVE Rainbow itself. (Cazaubon et al. 2021, Vascular Health and Risk Management)

Adults with chronic venous disorders.

Citrus flavonoid fractions supported venous tone and reduced leg heaviness and swelling, the basis for the microcirculation positioning of the citrus component.

2
Anthocyanins and Photoaged Skin — Review
PubMed

Comprehensive review of anthocyanins for photoaged skin. This is evidence for the anthocyanin component, not a trial of the finished blend. (Guo et al. 2024, Foods)

Laboratory and human skin research.

Anthocyanins showed antioxidant and skin-protective activity relevant to the blend's beauty-from-within positioning.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated at the studied dose.
Mild digestive upset is occasionally reported with plant polyphenol or enzyme blends.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Blood thinners (such as warfarin) — bromelain may add to their blood-thinning effect; consult your doctor.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

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Frequently asked questions about SelectSIEVE® Rainbow (Black Rice & Citrus Polyphenol Complex — Roelmi HPC)

What is SelectSIEVE Rainbow?

SelectSIEVE® Rainbow is an oral beauty-from-within complex from Roelmi HPC that combines anthocyanins from black rice, flavonoids from citrus, and fibers and proteolytic enzymes from kiwi and pineapple. It is positioned to support skin tone, elasticity, and healthy microcirculation.

What is SelectSIEVE Rainbow used for?

SelectSIEVE Rainbow is researched primarily for Hair, Skin & Nails and Antioxidant. The anthocyanins and polyphenols in the blend act as antioxidants that help support skin tone and elasticity from the inside.

What is the recommended dosage of SelectSIEVE Rainbow?

The clinically studied dose is 300 mg per day. Always follow the product label and check with a healthcare provider for personal advice.

Is SelectSIEVE Rainbow safe, and does it have side effects?

For most healthy adults, SelectSIEVE Rainbow is well tolerated at studied doses. Reported effects can include: Generally well-tolerated at the studied dose. Mild digestive upset is occasionally reported with plant polyphenol or enzyme blends. It may also interact with some medications. SelectSIEVE Rainbow is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does SelectSIEVE Rainbow interact with any medications?

Possible interactions include: Blood thinners (such as warfarin) — bromelain may add to their blood-thinning effect; consult your doctor. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for SelectSIEVE Rainbow?

NutraSmarts rates the evidence for SelectSIEVE Rainbow as Limited (2 out of 5). It is backed by 2 clinical trials and 4 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(4 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Cazaubon M, Benigni JP, Steinbruch M, et al. Is There a Difference in the Clinical Efficacy of Diosmin and Micronized Purified Flavonoid Fraction for the Treatment of Chronic Venous Disorders? Review of Available Evidence. Vasc Health Risk Manag. 2021;17:591-600..PubMedUsed to support: Component evidence: citrus flavonoids support venous tone and microcirculation.
  2. Guo X, He L, Sun J, et al. Exploring the Potential of Anthocyanins for Repairing Photoaged Skin: A Comprehensive Review. Foods. 2024;13(21)..PubMedUsed to support: Component evidence: anthocyanins support skin against photoaging (beauty-from-within).
  3. Chen T, Xie L, Wang G, et al. Anthocyanins-natural pigment of colored rice bran: Composition and biological activities. Food Res Int. 2024;175:113722..PubMedUsed to support: Component evidence: black and colored rice anthocyanins provide antioxidant activity.
  4. Hikisz P, Bernasinska-Slomczewska J. Beneficial Properties of Bromelain. Nutrients. 2021;13(12)..PubMedUsed to support: Component evidence: bromelain (pineapple enzyme) supports a normal inflammatory response.