Home Ingredients Glycyrrhizina (Licorice Flavonoids — BGG)
Hair, Skin & NailsAntioxidantAnti-Inflammatory

Glycyrrhizina (Licorice Flavonoids — BGG)

Glycyrrhiza glabra
Evidence Level
Moderate
1 Clinical Trial
5 Documented Benefits
3/5 Evidence Score

Glycyrrhizina is BGG's LICORICE FLAVONOID extract from Glycyrrhiza glabra — distinguished from generic licorice by FLAVONOID-RICH STANDARDIZATION rather than glycyrrhizin-dominant profile. Reduces glycyrrhizin content to minimize blood pressure and aldosterone concerns while preserving bioactive flavonoids (glabridin, licochalcones). Used for: skin health, oral care, antioxidant defense, anti-inflammatory applications.

Studied Dose Per BGG product specification
Active Compound Licorice flavonoids (glabridin, licochalcones) reduced glycyrrhizin

Benefits

Skin Brightening (Glabridin)

Glabridin (licorice flavonoid) inhibits tyrosinase — relevant to skin brightening and hyperpigmentation; used in skincare formulations.

Supported by Trial 1

Anti-Inflammatory Skin Effects

Licorice flavonoids reduce inflammatory markers in skin; relevant to inflammatory skin conditions.

Supported by Trial 1

Reduced Glycyrrhizin (Safety Distinction)

Standard licorice extracts contain glycyrrhizin — causes blood pressure increase and aldosterone effects at high/chronic doses; Glycyrrhizina's flavonoid-focused approach minimizes these concerns while preserving bioactive flavonoids.

Supported by Trial 1

Oral Care Applications

Licochalcones have antimicrobial activity relevant to oral care; reduces bad breath and gingival inflammation.

Antioxidant Activity

Multiple flavonoid antioxidants provide cellular protection.

Supported by Trial 1

Mechanism of action

1

Glabridin Tyrosinase Inhibition

Glabridin is one of most potent natural tyrosinase inhibitors — reduces melanin production; mechanism for skin brightening applications.

2

Anti-Inflammatory Activity

Multiple licorice flavonoids reduce inflammatory pathway activation; relevant to skin and other applications.

3

Antimicrobial Activity

Licochalcones have documented antimicrobial activity against oral and skin pathogens.

4

Glycyrrhizin Reduction

Standard licorice's glycyrrhizin causes pseudoaldosteronism (blood pressure increase, potassium loss, edema) at high/chronic doses; Glycyrrhizina's processed approach minimizes these effects.

Clinical trials

1
Glabridin for Skin Brightening — Multiple Studies
PubMed

Multiple studies of glabridin and licorice flavonoids on skin pigmentation.

Adults with hyperpigmentation concerns.

Skin brightening effects; reduction in melanin markers.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated when glycyrrhizin reduced.
Mild GI distress (rare).
Allergic reactions rare.
STANDARD LICORICE WARNING (less applicable to reduced-glycyrrhizin Glycyrrhizina): hypertension, hypokalemia, edema with glycyrrhizin-rich products.

Important Drug interactions

Antihypertensives — concern minimized with reduced glycyrrhizin but residual considerations.
Diuretics — potassium considerations.
Corticosteroids — interactions with hormonal pathways.
Pregnancy — AVOID concentrated licorice extracts in pregnancy (preterm labor risk with glycyrrhizin); reduced-glycyrrhizin safer but consult.
Lactation — limited data.
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Frequently asked questions about Glycyrrhizina (Licorice Flavonoids — BGG)

What is Glycyrrhizina (Licorice Flavonoids — BGG)?

Glycyrrhizina is BGG's LICORICE FLAVONOID extract from Glycyrrhiza glabra — distinguished from generic licorice by FLAVONOID-RICH STANDARDIZATION rather than glycyrrhizin-dominant profile.

What does Glycyrrhizina (Licorice Flavonoids — BGG) do?

Glabridin is one of most potent natural tyrosinase inhibitors — reduces melanin production; mechanism for skin brightening applications. In clinical research, Glycyrrhizina (Licorice Flavonoids — BGG) has been studied for skin brightening (glabridin), anti-inflammatory skin effects, reduced glycyrrhizin (safety distinction).

Who should take Glycyrrhizina (Licorice Flavonoids — BGG)?

Glycyrrhizina (Licorice Flavonoids — BGG) may be most relevant for people interested in hair, skin & nails, antioxidant, anti-inflammatory. It has been clinically studied for skin brightening (glabridin), anti-inflammatory skin effects, reduced glycyrrhizin (safety distinction). As with any supplement, consult your healthcare provider before starting, especially if you have medical conditions or take prescription medications.

How long does Glycyrrhizina (Licorice Flavonoids — BGG) take to work?

Most clinical trial effects appear over weeks of consistent use; individual response varies. Acute or same-day effects (where applicable) typically appear within hours, but most cumulative benefits — particularly those affecting biomarkers, mood, sleep quality, or chronic symptoms — require 4-12 weeks of regular use to fully assess. If you don't notice benefit after 12 weeks at the appropriate dose, it may not be your responder.

When is the best time to take Glycyrrhizina (Licorice Flavonoids — BGG)?

Glycyrrhizina (Licorice Flavonoids — BGG) can typically be taken with breakfast or dinner — taking with food reduces GI sensitivity for most supplements. Specific timing matters less than daily consistency for cumulative effects. Always check product labeling and follow personalized guidance from your healthcare provider.

Is Glycyrrhizina (Licorice Flavonoids — BGG) worth taking?

Glycyrrhizina (Licorice Flavonoids — BGG) has moderate clinical evidence (Evidence Level 3/5 on NutraSmarts) — meaningful trial support exists, though results are less consistent than top-tier ingredients. Whether it's worth taking depends on your specific goals, what you've already tried, your budget, and your overall supplement strategy. The honest framing: no supplement is essential for most people, and lifestyle factors (sleep, exercise, diet, stress management) typically produce larger effects than any single supplement. Glycyrrhizina (Licorice Flavonoids — BGG) is most worth trying if its evidence-supported uses align with your specific goals.

What is the recommended dosage of Glycyrrhizina (Licorice Flavonoids — BGG)?

The clinically studied dose for Glycyrrhizina (Licorice Flavonoids — BGG) is Per BGG product specification. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Glycyrrhizina (Licorice Flavonoids — BGG) used for?

Glycyrrhizina (Licorice Flavonoids — BGG) is studied for skin brightening (glabridin), anti-inflammatory skin effects, reduced glycyrrhizin (safety distinction). Glabridin (licorice flavonoid) inhibits tyrosinase — relevant to skin brightening and hyperpigmentation; used in skincare formulations.